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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: FAM184A

Summary for FAM184A

Gene information	Gene symbol	FAM184A
	Ensembl ID	ENSG00000111879
	Entrez ID	79632
	Gene name	family with sequence similarity 184 member A
	Synonyms	C6orf60\|FLJ13942
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: FAM184A

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE115251	Kelly cell line	Cell line	Neuroblastoma	Neuroblastoma	Targeted therapy	TAE684	NA	Malignant cells	0.323786	0.00e+00

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Expression of FAM184A in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to FAM184A

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating FAM184A

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
FAM184A	hsa-miR-3941	97.7435	NM_024581
FAM184A	hsa-miR-128-3p	97.1522	NM_001100411
FAM184A	hsa-miR-216a-3p	97.1522	NM_001100411
FAM184A	hsa-miR-3681-3p	96.9181	NM_001100411
FAM184A	hsa-miR-513a-5p	96.2775	NM_001100411
FAM184A	hsa-miR-372-5p	93.8301	NM_024581
FAM184A	hsa-miR-466	93.6878	NM_001100411
FAM184A	hsa-miR-4672	93.5247	NM_001100411
FAM184A	hsa-miR-9985	93.2686	NM_001100411
FAM184A	hsa-miR-27b-3p	93.2686	NM_001100411
FAM184A	hsa-miR-27a-3p	93.2686	NM_001100411
FAM184A	hsa-miR-8485	92.1534	NM_024581
FAM184A	hsa-miR-4282	91.4191	NM_001100411
FAM184A	hsa-miR-524-5p	91.0869	NM_001100411
FAM184A	hsa-miR-520d-5p	91.0869	NM_001100411
FAM184A	hsa-miR-323b-3p	90.3643	NM_001100411
FAM184A	hsa-miR-6758-3p	89.1333	NM_024581
FAM184A	hsa-miR-603	87.268	NM_024581
FAM184A	hsa-miR-329-3p	87.268	NM_024581
FAM184A	hsa-miR-362-3p	87.268	NM_024581
FAM184A	hsa-miR-5688	86.3017	NM_001100411
FAM184A	hsa-miR-548c-3p	83.2707	NM_001100411
FAM184A	hsa-miR-4789-3p	83.1441	NM_024581
FAM184A	hsa-miR-7-1-3p	82.6962	NM_001100411
FAM184A	hsa-miR-495-3p	82.6962	NM_001100411
FAM184A	hsa-miR-7-2-3p	82.6962	NM_001100411

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Motifs and transcription factors (TFs) regulating FAM184A

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
FAM184A	taipale_tf_pairs__E2F1_HES7_RRCRCGYGYNNNNSGCGCSN_CAP_repr	E2F1; HES7 (directAnnotation).
FAM184A	kznf__ZNF25_Imbeault2017_OM_MEME	ZNF25 (directAnnotation).
FAM184A	taipale_tf_pairs__ETV5_HES7_NNCACGTGNNNNCCGGAANN_CAP	ETV5; HES7 (directAnnotation).
FAM184A	kznf__ZFP57_Imbeault2017_RP_ChIP-seq	ZFP57 (directAnnotation).
FAM184A	kznf__ZNF777_Imbeault2017_RP_ChIP-seq	ZNF777 (directAnnotation).
FAM184A	metacluster_67.2	ZNF501 (directAnnotation). ACAA1; E2F2; E2F2; E2F3; E2F3; FOXN4 (inferredBy_Orthology).
FAM184A	cisbp__M07938	E2F1 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."