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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: FAM110B

Summary for FAM110B

Gene information	Gene symbol	FAM110B
	Ensembl ID	ENSG00000169122
	Entrez ID	90362
	Gene name	family with sequence similarity 110 member B
	Synonyms	C8orf72\|MGC39325
	Gene type	protein_coding
	UniProtAcc	Q8TC76

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Dataset with differentially expressed gene: FAM110B

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	-0.988399	2.24e-02

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Expression of FAM110B in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to FAM110B

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating FAM110B

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
FAM110B	hsa-miR-8076	93.2446	NM_147189
FAM110B	hsa-miR-5582-3p	92.7783	NM_147189
FAM110B	hsa-miR-30d-5p	92.6163	NM_147189
FAM110B	hsa-miR-30a-5p	92.6163	NM_147189
FAM110B	hsa-miR-30e-5p	92.6163	NM_147189
FAM110B	hsa-miR-30c-5p	92.6163	NM_147189
FAM110B	hsa-miR-30b-5p	92.6163	NM_147189
FAM110B	hsa-miR-4724-5p	92.3231	NM_147189
FAM110B	hsa-miR-10526-3p	92.2199	NM_147189
FAM110B	hsa-miR-6809-3p	90.2578	NM_147189
FAM110B	hsa-miR-18b-3p	89.5213	NM_147189
FAM110B	hsa-miR-3190-3p	88.9944	NM_147189
FAM110B	hsa-miR-3911	88.4884	NM_147189
FAM110B	hsa-miR-6885-3p	85.1543	NM_147189
FAM110B	hsa-miR-2277-5p	84.9125	NM_147189
FAM110B	hsa-miR-891b	84.5006	NM_147189
FAM110B	hsa-miR-5003-5p	83.4692	NM_147189
FAM110B	hsa-miR-6842-3p	83.02	NM_147189
FAM110B	hsa-miR-4524b-3p	82.6275	NM_147189
FAM110B	hsa-miR-16-1-3p	82.3961	NM_147189
FAM110B	hsa-miR-147a	82.0219	NM_147189
FAM110B	hsa-miR-4755-3p	81.8225	NM_147189
FAM110B	hsa-miR-3671	80.668	NM_147189

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Motifs and transcription factors (TFs) regulating FAM110B

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."