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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: EOGT

Summary for EOGT

Gene information	Gene symbol	EOGT
	Ensembl ID	ENSG00000163378
	Entrez ID	285203
	Gene name	EGF domain specific O-linked N-acetylglucosamine transferase
	Synonyms	AER61\|C3orf64\|FLJ33770
	Gene type	protein_coding
	UniProtAcc	Q5NDL2

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Dataset with differentially expressed gene: EOGT

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE108397	451Lu cell line	Cell line	Melanoma	Melanoma	Targeted therapy	PLX-4720	NA	Malignant cells	-0.266124	8.12e-38

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Expression of EOGT in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to EOGT

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating EOGT

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
EOGT	hsa-miR-6867-5p	99.9997	NM_001278689
EOGT	hsa-miR-3163	98.774	NM_001278689
EOGT	hsa-miR-3671	96.021	NM_001278689
EOGT	hsa-miR-137-3p	95.9848	NM_001278689
EOGT	hsa-miR-3121-3p	94.9626	NM_001278689
EOGT	hsa-miR-12136	94.7897	NM_001278689
EOGT	hsa-miR-6515-3p	94.6551	NM_001278689
EOGT	hsa-miR-148a-3p	94.2271	NM_001278689
EOGT	hsa-miR-152-3p	94.2271	NM_001278689
EOGT	hsa-miR-148b-3p	94.2271	NM_001278689
EOGT	hsa-miR-152-5p	93.9363	NM_001278689
EOGT	hsa-miR-3182	93.3025	NM_001278689
EOGT	hsa-miR-3662	93.0079	NM_001278689
EOGT	hsa-miR-6776-5p	92.8666	NM_001278689
EOGT	hsa-miR-548aw	92.6904	NM_001278689
EOGT	hsa-miR-507	91.919	NM_001278689
EOGT	hsa-miR-320c	91.4903	NM_001278689
EOGT	hsa-miR-320b	91.4903	NM_001278689
EOGT	hsa-miR-320d	91.4903	NM_001278689
EOGT	hsa-miR-320a-3p	91.4903	NM_001278689
EOGT	hsa-miR-19b-3p	90.6407	NM_001278689
EOGT	hsa-miR-19a-3p	90.6407	NM_001278689
EOGT	hsa-miR-1273h-5p	90.1987	NM_001278689
EOGT	hsa-miR-557	90.0458	NM_001278689
EOGT	hsa-miR-103a-1-5p	89.8171	NM_001278689
EOGT	hsa-miR-103a-2-5p	89.8171	NM_001278689
EOGT	hsa-miR-7158-3p	89.6825	NM_001278689
EOGT	hsa-miR-30d-3p	88.2622	NM_001278689
EOGT	hsa-miR-30e-3p	88.2622	NM_001278689
EOGT	hsa-miR-30a-3p	88.2622	NM_001278689
EOGT	hsa-miR-4276	87.8779	NM_001278689
EOGT	hsa-miR-454-3p	87.8231	NM_001278689
EOGT	hsa-miR-548u	87.6193	NM_001278689
EOGT	hsa-miR-3975	87.5498	NM_001278689
EOGT	hsa-miR-7161-5p	87.4069	NM_001278689
EOGT	hsa-miR-1468-3p	87.2138	NM_001278689
EOGT	hsa-miR-12124	86.6906	NM_001278689
EOGT	hsa-miR-6780a-5p	86.5579	NM_001278689
EOGT	hsa-miR-6779-5p	86.3669	NM_001278689
EOGT	hsa-miR-3689c	86.3669	NM_001278689
EOGT	hsa-miR-3689b-3p	86.3669	NM_001278689
EOGT	hsa-miR-30b-3p	86.3669	NM_001278689
EOGT	hsa-miR-3689a-3p	86.3669	NM_001278689
EOGT	hsa-miR-7152-5p	86.2232	NM_001278689
EOGT	hsa-miR-4429	85.7895	NM_001278689
EOGT	hsa-miR-607	85.6479	NM_001278689
EOGT	hsa-miR-188-3p	85.0311	NM_001278689
EOGT	hsa-miR-301b-3p	84.3968	NM_001278689
EOGT	hsa-miR-301a-3p	84.3968	NM_001278689
EOGT	hsa-miR-6128	84.0261	NM_001278689

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Motifs and transcription factors (TFs) regulating EOGT

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
EOGT	metacluster_7.13	ZFX (directAnnotation).
EOGT	cisbp__M01863	ZNF711 (inferredBy_Orthology).
EOGT	metacluster_151.2	ZNF23 (directAnnotation).
EOGT	metacluster_170.2	KLF1; KLF10; KLF10; KLF11; KLF11; KLF11; KLF12; KLF12; KLF14; KLF15; KLF17; KLF2; KLF5; KLF7; KLF7; KLF8; MAZ; MAZ; PATZ1; SP1; SP1; SP1; SP2; SP2; SP2; SP2; SP2; SP2; SP2; SP2; SP4; SP4; SP5; SP6; SP7; SP8; SP9; ZNF281 (directAnnotation). E2F1; E2F4; KLF10; KLF13; KLF14; KLF17; KLF2; KLF7; SP1; SP1; SP3; SP4; SP5; SP6; SP7 (inferredBy_Orthology).
EOGT	metacluster_155.23	BCL11B; ZNF711; ZNF711 (directAnnotation). ZFY (inferredBy_Orthology).
EOGT	metacluster_144.3	ZNF704; ZNF704 (directAnnotation).
EOGT	hdpi__ETV4	ETV4 (directAnnotation).
EOGT	homer__TWVGGTCCGC_HINFP	HINFP (directAnnotation).
EOGT	metacluster_135.10	MBD2; MBD2; MECP2; MECP2 (directAnnotation).
EOGT	jaspar__MA0079.5	SP1 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."