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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor
	Acts as a drug target< (This gene does not contain this module)

Gene: ELF5

Summary for ELF5

Gene information	Gene symbol	ELF5
	Ensembl ID	ENSG00000135374
	Entrez ID	2001
	Gene name	E74 like ETS transcription factor 5
	Synonyms	NA
	Gene type	protein_coding
	UniProtAcc	Q9UKW6

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Dataset with differentially expressed gene: ELF5

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE163836	FCIBC02 cell line	Cell line	Breast cancer	Inflammatory breast cancer	Chemotherapy	paclitaxel	NA	Malignant cells	0.369013	6.86e-39

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Expression of ELF5 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to ELF5

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ELF5

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
ELF5	hsa-miR-4760-3p	91.3699	NM_198381
ELF5	hsa-miR-657	88.676	NM_001422
ELF5	hsa-miR-6729-3p	87.5272	NM_001422
ELF5	hsa-miR-3194-5p	87.2265	NM_001422
ELF5	hsa-miR-1253	87.1474	NM_001422
ELF5	hsa-miR-6830-5p	86.4031	NM_001422
ELF5	hsa-miR-1246	86.2722	NM_198381
ELF5	hsa-miR-3059-3p	86.2163	NM_001422
ELF5	hsa-miR-4771	83.5733	NM_198381
ELF5	hsa-miR-371b-5p	82.7175	NM_001422
ELF5	hsa-miR-373-5p	82.7175	NM_001422
ELF5	hsa-miR-616-5p	82.7175	NM_001422
ELF5	hsa-miR-492	82.3906	NM_001422
ELF5	hsa-miR-4445-5p	81.4051	NM_001422
ELF5	hsa-miR-4664-3p	80.1422	NM_001422

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Motifs and transcription factors (TFs) regulating ELF5

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

TF	motif	Expression	Cell type	Dataset	Timepoint
ELF5	metacluster_166.4	up	Malignant cells	GSE163836	NA

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."