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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: CTTNBP2NL

Summary for CTTNBP2NL

Gene information	Gene symbol	CTTNBP2NL
	Ensembl ID	ENSG00000143079
	Entrez ID	55917
	Gene name	CTTNBP2 N-terminal like
	Synonyms	DKFZp547A023
	Gene type	protein_coding
	UniProtAcc	Q9P2B4

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Dataset with differentially expressed gene: CTTNBP2NL

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	0.741862	1.44e-03

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Expression of CTTNBP2NL in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to CTTNBP2NL

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating CTTNBP2NL

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
CTTNBP2NL	hsa-miR-8485	99.8221	NM_018704
CTTNBP2NL	hsa-miR-1185-2-3p	99.738	NM_018704
CTTNBP2NL	hsa-miR-1185-1-3p	99.738	NM_018704
CTTNBP2NL	hsa-let-7f-2-3p	99.6973	NM_018704
CTTNBP2NL	hsa-miR-548c-3p	97.3454	NM_018704
CTTNBP2NL	hsa-miR-4698	96.5718	NM_018704
CTTNBP2NL	hsa-miR-4262	96.4605	NM_018704
CTTNBP2NL	hsa-miR-20a-3p	95.6957	NM_018704
CTTNBP2NL	hsa-miR-345-5p	95.5523	NM_018704
CTTNBP2NL	hsa-miR-3680-3p	94.902	NM_018704
CTTNBP2NL	hsa-miR-1297	94.4055	NM_018704
CTTNBP2NL	hsa-miR-181a-5p	94.2622	NM_018704
CTTNBP2NL	hsa-miR-181d-5p	94.2622	NM_018704
CTTNBP2NL	hsa-miR-181b-5p	94.2622	NM_018704
CTTNBP2NL	hsa-miR-181c-5p	94.2622	NM_018704
CTTNBP2NL	hsa-miR-5002-5p	94.1449	NM_018704
CTTNBP2NL	hsa-miR-4269	93.8975	NM_018704
CTTNBP2NL	hsa-miR-6715b-5p	93.8975	NM_018704
CTTNBP2NL	hsa-miR-6504-3p	93.466	NM_018704
CTTNBP2NL	hsa-miR-1-3p	93.3871	NM_018704
CTTNBP2NL	hsa-miR-206	93.3871	NM_018704
CTTNBP2NL	hsa-miR-7110-3p	93.2521	NM_018704
CTTNBP2NL	hsa-miR-10399-5p	92.8222	NM_018704
CTTNBP2NL	hsa-miR-4519	92.6146	NM_018704
CTTNBP2NL	hsa-miR-6873-3p	92.4498	NM_018704
CTTNBP2NL	hsa-miR-26b-5p	92.2783	NM_018704
CTTNBP2NL	hsa-miR-26a-5p	92.2783	NM_018704
CTTNBP2NL	hsa-miR-8084	92.2587	NM_018704
CTTNBP2NL	hsa-miR-6128	92.1492	NM_018704
CTTNBP2NL	hsa-miR-218-5p	92.044	NM_018704
CTTNBP2NL	hsa-miR-613	91.1432	NM_018704
CTTNBP2NL	hsa-miR-4267	90.9632	NM_018704
CTTNBP2NL	hsa-miR-4786-3p	90.8481	NM_018704
CTTNBP2NL	hsa-miR-4692	90.3136	NM_018704
CTTNBP2NL	hsa-miR-4742-5p	90.3136	NM_018704
CTTNBP2NL	hsa-miR-4465	89.9914	NM_018704
CTTNBP2NL	hsa-miR-583	89.9353	NM_018704
CTTNBP2NL	hsa-miR-891b	89.6784	NM_018704
CTTNBP2NL	hsa-miR-589-3p	89.2919	NM_018704
CTTNBP2NL	hsa-miR-4514	89.281	NM_018704
CTTNBP2NL	hsa-miR-10527-5p	89.0102	NM_018704
CTTNBP2NL	hsa-miR-876-5p	88.9593	NM_018704
CTTNBP2NL	hsa-miR-29b-2-5p	88.7995	NM_018704
CTTNBP2NL	hsa-miR-3167	88.6638	NM_018704
CTTNBP2NL	hsa-miR-544a	88.4128	NM_018704
CTTNBP2NL	hsa-miR-579-3p	88.2889	NM_018704
CTTNBP2NL	hsa-miR-664b-3p	88.2889	NM_018704
CTTNBP2NL	hsa-miR-3065-3p	88.0115	NM_018704
CTTNBP2NL	hsa-miR-155-5p	87.1955	NM_018704
CTTNBP2NL	hsa-miR-153-5p	86.9479	NM_018704

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Motifs and transcription factors (TFs) regulating CTTNBP2NL

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
CTTNBP2NL	metacluster_195.2	EGR2; KLF10; KLF10; KLF11; KLF11; KLF11; KLF13; KLF13; KLF13; KLF13; KLF13; KLF14; KLF14; KLF14; KLF14; KLF14; KLF15; KLF15; KLF16; KLF3; KLF8; KLF9; KLF9; KLF9; SP1; SP1; SP1; SP3; SP3; SP4; SP8; SP8; SP8; SP9; SP9 (directAnnotation). EGR1; KLF1; KLF12; KLF13; KLF14; KLF14; KLF14; KLF14; KLF14; KLF14; KLF16; KLF17; KLF17; KLF17; KLF17; KLF18; KLF18; KLF18; KLF18; KLF18; KLF18; KLF2; KLF2; KLF2; KLF3; KLF4; KLF5; KLF5; KLF5; KLF6; KLF7; KLF7; KLF8; KLF9; SP1; SP3; SP4; SP4; SP5; SP5; SP5; SP6; SP7; SP8; SP9 (inferredBy_Orthology).
CTTNBP2NL	transfac_pro__M04617	ZBTB7A (directAnnotation).
CTTNBP2NL	metacluster_3.5	KLF14; KLF15; KLF15; KLF16 (directAnnotation).
CTTNBP2NL	taipale_cyt_meth__ZNF460_NRMCGCCCCCCGN_eDBD_meth	ZNF460 (directAnnotation).
CTTNBP2NL	transfac_pro__M07387	ZBTB7A (directAnnotation).
CTTNBP2NL	transfac_pro__M07436	WT1 (directAnnotation).
CTTNBP2NL	transfac_pro__M07461	KLF1; KLF10; KLF11; KLF12; KLF13; KLF15; KLF16; KLF17; KLF2; KLF3; KLF4; KLF5; KLF6; KLF7; KLF8; KLF9 (directAnnotation).
CTTNBP2NL	swissregulon__hs__CHD1	CHD1 (directAnnotation).
CTTNBP2NL	hdpi__HIP2	UBE2K (directAnnotation).
CTTNBP2NL	taipale_tf_pairs__GCM1_SPDEF_RTGNKGGCGGAWG_CAP_repr	GCM1; SPDEF (directAnnotation).
CTTNBP2NL	metacluster_170.2	KLF1; KLF10; KLF10; KLF11; KLF11; KLF11; KLF12; KLF12; KLF14; KLF15; KLF17; KLF2; KLF5; KLF7; KLF7; KLF8; MAZ; MAZ; PATZ1; SP1; SP1; SP1; SP2; SP2; SP2; SP2; SP2; SP2; SP2; SP2; SP4; SP4; SP5; SP6; SP7; SP8; SP9; ZNF281 (directAnnotation). E2F1; E2F4; KLF10; KLF13; KLF14; KLF17; KLF2; KLF7; SP1; SP1; SP3; SP4; SP5; SP6; SP7 (inferredBy_Orthology).
CTTNBP2NL	transfac_pro__M04893	TAF1 (directAnnotation).
CTTNBP2NL	transfac_pro__M03876	ZBTB33 (directAnnotation).
CTTNBP2NL	metacluster_15.2	E2F1; E2F1; E2F1; E2F1; E2F1; E2F3; E2F4; E2F4; E2F4; E2F6; E2F6; E2F6; E2F6; E2F6; E2F6; E2F6; E2F7; TFDP1; TFDP2; ZNF566; ZNF566; ZNF574 (directAnnotation). E2F3; E2F3; E2F4 (inferredBy_Orthology).
CTTNBP2NL	metacluster_133.1	ZNF304; ZNF304; ZSCAN22 (directAnnotation).
CTTNBP2NL	kznf__ZNF441_Imbeault2017_RP_RCADE	ZNF441 (directAnnotation).
CTTNBP2NL	transfac_pro__M01219	SP1 (directAnnotation). SP3 (inferredBy_Orthology).
CTTNBP2NL	metacluster_3.7	SP1; SP1; SP1; SP1; SP1; SP1; SP1; SP1; SP2; SP2; SP2; SP2; SP3; SP3; SP3; SP4; SP4; SP4; SP4; SP4; SP4; SP5 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."