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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: CTDSP2

Summary for CTDSP2

Gene information	Gene symbol	CTDSP2
	Ensembl ID	ENSG00000175215
	Entrez ID	10106
	Gene name	CTD small phosphatase 2
	Synonyms	OS4\|PSR2\|SCP2
	Gene type	protein_coding
	UniProtAcc	O14595

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Dataset with differentially expressed gene: CTDSP2

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE175716	PDX	Tumor tissue	Liver cancer	Advanced hepatocellular carcinoma	Targeted therapy	sorafenib	NA	Malignant cells	-0.376243	2.59e-38
GSE115251	Kelly cell line	Cell line	Neuroblastoma	Neuroblastoma	Targeted therapy	TAE684	NA	Malignant cells	0.331417	0.00e+00

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Expression of CTDSP2 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to CTDSP2

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating CTDSP2

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
CTDSP2	hsa-miR-6069	96.8364	NM_005730
CTDSP2	hsa-miR-3529-3p	94.3277	NM_005730
CTDSP2	hsa-miR-212-5p	92.9754	NM_005730
CTDSP2	hsa-miR-506-3p	90.7047	NM_005730
CTDSP2	hsa-miR-345-3p	88.7726	NM_005730
CTDSP2	hsa-miR-3714	88.4596	NM_005730
CTDSP2	hsa-miR-128-3p	88.3727	NM_005730
CTDSP2	hsa-miR-216a-3p	88.3727	NM_005730
CTDSP2	hsa-miR-875-3p	88.3396	NM_005730
CTDSP2	hsa-miR-3189-3p	88.3352	NM_005730
CTDSP2	hsa-miR-124-3p	88.189	NM_005730
CTDSP2	hsa-miR-3179	87.5653	NM_005730
CTDSP2	hsa-miR-6715b-3p	87.3034	NM_005730
CTDSP2	hsa-miR-5008-5p	86.5864	NM_005730
CTDSP2	hsa-miR-450a-1-3p	85.6886	NM_005730
CTDSP2	hsa-miR-4290	85.0526	NM_005730
CTDSP2	hsa-miR-137-3p	84.1603	NM_005730
CTDSP2	hsa-miR-4747-5p	83.766	NM_005730
CTDSP2	hsa-miR-548an	83.5183	NM_005730
CTDSP2	hsa-miR-3681-3p	83.4098	NM_005730
CTDSP2	hsa-miR-5196-5p	81.8455	NM_005730
CTDSP2	hsa-miR-634	81.4494	NM_005730
CTDSP2	hsa-miR-6828-5p	80.6203	NM_005730
CTDSP2	hsa-miR-6715a-3p	80.313	NM_005730
CTDSP2	hsa-miR-5582-5p	80.2706	NM_005730

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Motifs and transcription factors (TFs) regulating CTDSP2

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
CTDSP2	taipale_tf_pairs__HOXB2_ETV4_ACCGGAAATGAN_CAP	ETV4; HOXB2 (directAnnotation).
CTDSP2	metacluster_3.14	WT1; WT1 (directAnnotation).
CTDSP2	metacluster_135.11	NR2C2 (directAnnotation).
CTDSP2	metacluster_198.3	ZFP64 (directAnnotation).
CTDSP2	transfac_pro__M01219	SP1 (directAnnotation). SP3 (inferredBy_Orthology).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."