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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target

Gene: CTDSP1

Summary for CTDSP1

Gene information	Gene symbol	CTDSP1
	Ensembl ID	ENSG00000144579
	Entrez ID	58190
	Gene name	CTD small phosphatase 1
	Synonyms	NLIIF\|SCP1
	Gene type	protein_coding
	UniProtAcc	Q9GZU7

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Dataset with differentially expressed gene: CTDSP1

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE164551	patients	Bone marrow aspirate	Multiple myeloma	Refractory multiple myeloma (MM)	Immunotherapy	CAR-T	NA	Mono/Macro	-0.336948	3.36e-17
GSE175716	PDX	Tumor tissue	Liver cancer	Advanced hepatocellular carcinoma	Targeted therapy	sorafenib	NA	Malignant cells	-0.273907	1.11e-22

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Expression of CTDSP1 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to CTDSP1

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating CTDSP1

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
CTDSP1	hsa-miR-124-3p	99.4601	NM_001206878
CTDSP1	hsa-miR-506-3p	99.3506	NM_001206878
CTDSP1	hsa-miR-605-3p	97.0842	NM_001206878
CTDSP1	hsa-miR-4264	91.661	NM_182642
CTDSP1	hsa-miR-6722-3p	90.6051	NM_182642
CTDSP1	hsa-miR-96-5p	90.2568	NM_001206878
CTDSP1	hsa-miR-1909-3p	90.2028	NM_182642
CTDSP1	hsa-miR-5698	89.9036	NM_182642
CTDSP1	hsa-miR-4723-5p	89.9036	NM_182642
CTDSP1	hsa-miR-6870-5p	89.9036	NM_182642
CTDSP1	hsa-miR-7111-5p	89.9036	NM_182642
CTDSP1	hsa-miR-765	89.6159	NM_182642
CTDSP1	hsa-miR-654-5p	88.7855	NM_182642
CTDSP1	hsa-miR-541-3p	88.7855	NM_182642
CTDSP1	hsa-miR-1271-5p	88.169	NM_001206878
CTDSP1	hsa-miR-12133	88.169	NM_001206878
CTDSP1	hsa-miR-6825-5p	88.1398	NM_182642
CTDSP1	hsa-miR-548c-3p	87.6714	NM_001206878
CTDSP1	hsa-miR-11181-3p	87.1862	NM_182642
CTDSP1	hsa-miR-4704-3p	86.6155	NM_182642
CTDSP1	hsa-miR-212-5p	86.2523	NM_001206878
CTDSP1	hsa-miR-3907	86.0929	NM_001206878
CTDSP1	hsa-miR-9851-3p	85.8883	NM_182642
CTDSP1	hsa-miR-6734-3p	85.2805	NM_182642
CTDSP1	hsa-miR-4753-3p	84.432	NM_182642
CTDSP1	hsa-miR-593-5p	84.3633	NM_182642
CTDSP1	hsa-miR-361-3p	84.0382	NM_001206878
CTDSP1	hsa-miR-6875-5p	83.3626	NM_182642
CTDSP1	hsa-miR-6851-5p	80.5326	NM_001206878

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Motifs and transcription factors (TFs) regulating CTDSP1

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
CTDSP1	cisbp__M01815	CEBPE (inferredBy_Orthology).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

Target name	Drug name	Drug ID	Drug type
CTDSP1	"Aspartate beryllium trifluoride"	DB04156	small molecule
CTDSP1	"Citric acid"	DB04272	small molecule

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1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."