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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: CSGALNACT1

Summary for CSGALNACT1

Gene information	Gene symbol	CSGALNACT1
	Ensembl ID	ENSG00000147408
	Entrez ID	55790
	Gene name	chondroitin sulfate N-acetylgalactosaminyltransferase 1
	Synonyms	ChGn\|CSGalNAcT-1\|FLJ11264
	Gene type	protein_coding
	UniProtAcc	Q8TDX6

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Dataset with differentially expressed gene: CSGALNACT1

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE189460	patients	Bone marrow aspirate	Multiple myeloma	Multiple myeloma (MM)	Targeted therapy	bortezomib + melphalan + prednisolone	pre	pDCs	0.337579	1.98e-03

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Expression of CSGALNACT1 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to CSGALNACT1

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating CSGALNACT1

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
CSGALNACT1	hsa-miR-5011-5p	99.673	NM_001130518
CSGALNACT1	hsa-miR-659-3p	99.1982	NM_001130518
CSGALNACT1	hsa-miR-4784	95.0866	NM_018371
CSGALNACT1	hsa-miR-3150b-3p	95.0866	NM_018371
CSGALNACT1	hsa-miR-190a-3p	95.0185	NM_018371
CSGALNACT1	hsa-miR-9-5p	91.6718	NM_001130518
CSGALNACT1	hsa-miR-5580-5p	90.8766	NM_018371
CSGALNACT1	hsa-miR-6868-5p	88.8095	NM_018371
CSGALNACT1	hsa-miR-3606-3p	88.7405	NM_018371
CSGALNACT1	hsa-miR-651-3p	87.6587	NM_001130518
CSGALNACT1	hsa-miR-7152-3p	87.5744	NM_018371
CSGALNACT1	hsa-miR-29b-2-5p	87.3851	NM_001130518
CSGALNACT1	hsa-miR-299-5p	86.2274	NM_001130518
CSGALNACT1	hsa-miR-513c-3p	85.7182	NM_018371
CSGALNACT1	hsa-miR-513a-3p	85.7182	NM_018371
CSGALNACT1	hsa-miR-30a-5p	85.583	NM_001130518
CSGALNACT1	hsa-miR-30c-5p	85.583	NM_001130518
CSGALNACT1	hsa-miR-30d-5p	85.583	NM_001130518
CSGALNACT1	hsa-miR-30b-5p	85.583	NM_001130518
CSGALNACT1	hsa-miR-30e-5p	85.583	NM_001130518
CSGALNACT1	hsa-miR-153-5p	85.4382	NM_018371
CSGALNACT1	hsa-miR-203b-3p	84.072	NM_018371
CSGALNACT1	hsa-miR-627-3p	82.8361	NM_018371
CSGALNACT1	hsa-miR-203a-3p	80.1987	NM_018371

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Motifs and transcription factors (TFs) regulating CSGALNACT1

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
CSGALNACT1	tfdimers__MD00263	STAT1; TCF7L1 (directAnnotation).
CSGALNACT1	jaspar__MA1951.1	FOS (directAnnotation).
CSGALNACT1	transfac_pro__M06765	ZNF629 (directAnnotation).
CSGALNACT1	tfdimers__MD00515	ARID3A; KLF4 (directAnnotation).
CSGALNACT1	dbtfbs__NCOA3_MCF-7_ENCSR573OJP_merged_N2	NCOA3 (directAnnotation).
CSGALNACT1	transfac_pro__M05574	ZFP92 (directAnnotation).
CSGALNACT1	tfdimers__MD00382	POU2F1; ZNF354C (directAnnotation).
CSGALNACT1	hdpi__THAP5	THAP5 (directAnnotation).
CSGALNACT1	hdpi__ZNF326	ZNF326 (directAnnotation).
CSGALNACT1	transfac_pro__M06275	ZNF284 (directAnnotation).
CSGALNACT1	metacluster_180.3	ATF2; ATF2; ATF2; ATF2; ATF3; ATF3; ATF4; ATF4; ATF6; ATF6B; ATF7; ATF7; BACH2; BATF3; BATF3; CREB1; CREB1; CREB3; FOSL1; FOSL2; JDP2; JUN; JUN; JUN; JUND; JUND; XBP1; ZBTB21 (directAnnotation). JDP2; JDP2; JUND (inferredBy_Orthology).
CSGALNACT1	transfac_pro__M06737	ZNF226 (directAnnotation).
CSGALNACT1	transfac_pro__M05895	ZNF454 (directAnnotation).
CSGALNACT1	hdpi__TCEAL2	TCEAL2 (directAnnotation).
CSGALNACT1	metacluster_148.1	ATF2; ATF2; ATF3; ATF3; ATF3; ATF3; ATF4; ATF4; ATF6; ATF6; ATF6B; ATF7; BATF3; BATF3; CREB1; CREB1; CREB1; CREB3; CREB3; CREB5; CREB5; CREB5; CREM; CREM; FOS; FOS; FOSB; FOSB; FOSB; FOSL1; JDP2; JDP2; JUN; JUN; JUN; JUNB; JUND; MAF; MAF; MAFA; MAFA; MAFF; MAFF; MAFF; MAFF; MAFG; MAFG; ZBTB21 (directAnnotation). ATF1; ATF1; ATF1; ATF1; ATF6; ATF6; ATF6; ATF6; ATF6B; ATF6B; ATF6B; ATF6B; CREB1; CREB1; CREB3; CREB3; CREB3; CREB3; CREB3L1; CREB3L1; CREB3L1; CREB3L1; CREB3L2; CREB3L2; CREB3L2; CREB3L2; CREB3L3; CREB3L3; CREB3L3; CREB3L3; CREB3L4; CREB3L4; CREB3L4; CREB3L4; CREM; CREM; CREM; CREM; JDP2; JUN; JUNB; JUND; MAFB (inferredBy_Orthology).
CSGALNACT1	hocomoco__RARB_HUMAN.H11MO.0.D	RARB (directAnnotation).
CSGALNACT1	tfdimers__MD00158	DBP; ZNF354C (directAnnotation).
CSGALNACT1	metacluster_7.7	SP2 (directAnnotation). KLF16 (inferredBy_Orthology).
CSGALNACT1	transfac_pro__M01252	E2F6 (directAnnotation).
CSGALNACT1	cisbp__M01742	MYF6 (inferredBy_Orthology).
CSGALNACT1	taipale_tf_pairs__RFX3_SREBF2_NNRGYAACNTCACGTGAY_CAP_repr	RFX3; SREBF2 (directAnnotation).
CSGALNACT1	tfdimers__MD00230	FOS; FOSB; FOSL1; FOSL2; JUN; JUNB; JUND; STAT1 (directAnnotation).
CSGALNACT1	tfdimers__MD00082	GATA1; GATA2; GATA3; GATA4; GATA5; GATA6; ZNF217 (directAnnotation).
CSGALNACT1	transfac_pro__M06326	ZNF841 (directAnnotation).
CSGALNACT1	transfac_pro__M01841	ESRRA (directAnnotation).
CSGALNACT1	kznf__ZNF614_Imbeault2017_RP_ChIP-seq	ZNF614 (directAnnotation).
CSGALNACT1	tfdimers__MD00228	PDX1; TFAP4 (directAnnotation).
CSGALNACT1	transfac_pro__M06611	ZNF560 (directAnnotation).
CSGALNACT1	taipale_tf_pairs__TFAP4_DLX3_NNCAGCTGNNNNNNNTAATTN_HT	DLX3; TFAP4 (directAnnotation).
CSGALNACT1	transfac_public__M00159	CEBPA (directAnnotation).
CSGALNACT1	transfac_pro__M06322	ZNF181 (directAnnotation).
CSGALNACT1	tfdimers__MD00051	GABPA; STAT6 (directAnnotation).
CSGALNACT1	transfac_pro__M01661	HBP1 (directAnnotation).
CSGALNACT1	hdpi__POU4F3	POU4F3 (directAnnotation).
CSGALNACT1	transfac_pro__M06257	ZNF616 (directAnnotation).
CSGALNACT1	transfac_pro__M05667	ZNF35 (directAnnotation).
CSGALNACT1	metacluster_111.4	ATF1; ATF1; ATF1; ATF1; ATF1; ATF1; ATF2; ATF2; ATF2; ATF2; ATF2; ATF2; ATF2; ATF2; ATF2; ATF2; ATF3; ATF3; ATF3; ATF3; ATF3; ATF4; ATF4; ATF5; ATF6; ATF6B; ATF7; ATF7; ATF7; BATF3; BATF3; CREB1; CREB1; CREB1; CREB1; CREB1; CREB1; CREB1; CREB1; CREB1; CREB1; CREB3; CREB3L4; CREB3L4; CREB5; CREB5; CREB5; CREM; CREM; CREM; CREM; CREM; FOSB; FOSL1; FOSL1; FOSL2; JDP2; JDP2; JDP2; JUN; JUNB; JUNB; JUNB; JUND; JUND; JUND; JUND; JUND; XBP1; XBP1; XBP1; ZNF629 (directAnnotation). ATF1; ATF1; ATF1; ATF2; ATF2; ATF3; ATF6; ATF6B; ATF7; ATF7; ATF7; ATF7-NPFF; ATF7-NPFF; ATF7-NPFF; ATF7-NPFF; BATF; BATF2; BATF3; CREB1; CREB1; CREB3; CREB3L1; CREB3L2; CREB3L3; CREB3L4; CREM; FOS; FOSB; FOSL1; FOSL2; JDP2; JDP2 (inferredBy_Orthology).
CSGALNACT1	nitta__so_TATCGC20NGCG_KG_NGATACGTATCN_m1_c3	SIX1 (inferredBy_Orthology).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."