Home

Download

Statistics

Landscape

Help

Contact

	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: CNTNAP3B

Summary for CNTNAP3B

Gene information	Gene symbol	CNTNAP3B
	Ensembl ID	ENSG00000154529
	Entrez ID	728577
	Gene name	contactin associated protein family member 3B
	Synonyms	NA
	Gene type	protein_coding
	UniProtAcc	NA

Top

Dataset with differentially expressed gene: CNTNAP3B

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	1.66272	4.96e-08

Top

Expression of CNTNAP3B in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

Top

Significant ligand-receptor pairs related to CNTNAP3B

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

Top

Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

Top

MicroRNAs (miRNA) regulating CNTNAP3B

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
CNTNAP3B	hsa-miR-590-3p	97.5225	NM_001201380
CNTNAP3B	hsa-miR-548aj-5p	97.4453	NM_001201380
CNTNAP3B	hsa-miR-548x-5p	97.4453	NM_001201380
CNTNAP3B	hsa-miR-548g-5p	97.4453	NM_001201380
CNTNAP3B	hsa-miR-5683	97.1043	NM_001201380
CNTNAP3B	hsa-miR-548f-5p	95.9815	NM_001201380
CNTNAP3B	hsa-miR-8063	95.1323	NM_001201380
CNTNAP3B	hsa-miR-216a-5p	93.3306	NM_001201380
CNTNAP3B	hsa-miR-3680-3p	91.2351	NM_001201380
CNTNAP3B	hsa-miR-4775	90.8042	NM_001201380
CNTNAP3B	hsa-miR-3190-3p	90.5507	NM_001201380
CNTNAP3B	hsa-miR-152-3p	89.2627	NM_001201380
CNTNAP3B	hsa-miR-148b-3p	89.2627	NM_001201380
CNTNAP3B	hsa-miR-148a-3p	89.2627	NM_001201380
CNTNAP3B	hsa-miR-431-5p	88.8081	NM_001201380
CNTNAP3B	hsa-miR-4725-3p	88.5783	NM_001201380
CNTNAP3B	hsa-miR-6780b-5p	88.5783	NM_001201380
CNTNAP3B	hsa-miR-4271	88.273	NM_001201380
CNTNAP3B	hsa-miR-1208	88.0684	NM_001201380
CNTNAP3B	hsa-miR-4751	87.8365	NM_001201380
CNTNAP3B	hsa-miR-4422	87.3366	NM_001201380
CNTNAP3B	hsa-miR-6715a-3p	86.5708	NM_001201380
CNTNAP3B	hsa-miR-16-2-3p	86.4374	NM_001201380
CNTNAP3B	hsa-miR-195-3p	86.4374	NM_001201380
CNTNAP3B	hsa-miR-153-5p	85.9603	NM_001201380
CNTNAP3B	hsa-miR-3671	85.4599	NM_001201380
CNTNAP3B	hsa-miR-3686	85.4406	NM_001201380
CNTNAP3B	hsa-miR-215-3p	84.5958	NM_001201380
CNTNAP3B	hsa-miR-26b-5p	83.4841	NM_001201380
CNTNAP3B	hsa-miR-26a-5p	83.4841	NM_001201380
CNTNAP3B	hsa-miR-1297	83.4841	NM_001201380
CNTNAP3B	hsa-miR-543	83.474	NM_001201380
CNTNAP3B	hsa-miR-6128	82.9328	NM_001201380
CNTNAP3B	hsa-miR-5581-3p	82.7557	NM_001201380
CNTNAP3B	hsa-miR-4262	82.2977	NM_001201380
CNTNAP3B	hsa-miR-4465	82.138	NM_001201380
CNTNAP3B	hsa-miR-4778-5p	81.7722	NM_001201380
CNTNAP3B	hsa-miR-4768-3p	81.2244	NM_001201380
CNTNAP3B	hsa-miR-1305	80.531	NM_001201380

Page: 1

Top

Motifs and transcription factors (TFs) regulating CNTNAP3B

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
CNTNAP3B	kznf__ZNF594_Schmitges2016_RCADE	ZNF594 (directAnnotation).
CNTNAP3B	metacluster_195.2	EGR2; KLF10; KLF10; KLF11; KLF11; KLF11; KLF13; KLF13; KLF13; KLF13; KLF13; KLF14; KLF14; KLF14; KLF14; KLF14; KLF15; KLF15; KLF16; KLF3; KLF8; KLF9; KLF9; KLF9; SP1; SP1; SP1; SP3; SP3; SP4; SP8; SP8; SP8; SP9; SP9 (directAnnotation). EGR1; KLF1; KLF12; KLF13; KLF14; KLF14; KLF14; KLF14; KLF14; KLF14; KLF16; KLF17; KLF17; KLF17; KLF17; KLF18; KLF18; KLF18; KLF18; KLF18; KLF18; KLF2; KLF2; KLF2; KLF3; KLF4; KLF5; KLF5; KLF5; KLF6; KLF7; KLF7; KLF8; KLF9; SP1; SP3; SP4; SP4; SP5; SP5; SP5; SP6; SP7; SP8; SP9 (inferredBy_Orthology).
CNTNAP3B	kznf__ZBTB14_Schmitges2016_RCADE	ZBTB14 (directAnnotation).
CNTNAP3B	transfac_pro__M04617	ZBTB7A (directAnnotation).
CNTNAP3B	metacluster_3.5	KLF14; KLF15; KLF15; KLF16 (directAnnotation).
CNTNAP3B	taipale_cyt_meth__ZNF460_NRMCGCCCCCCGN_eDBD_meth	ZNF460 (directAnnotation).
CNTNAP3B	taipale_cyt_meth__E2F2_NCGCGCGCGCM_eDBD_meth	E2F2 (directAnnotation).
CNTNAP3B	transfac_pro__M07387	ZBTB7A (directAnnotation).
CNTNAP3B	transfac_pro__M07436	WT1 (directAnnotation).
CNTNAP3B	transfac_pro__M07461	KLF1; KLF10; KLF11; KLF12; KLF13; KLF15; KLF16; KLF17; KLF2; KLF3; KLF4; KLF5; KLF6; KLF7; KLF8; KLF9 (directAnnotation).
CNTNAP3B	transfac_pro__M00716	ZBTB14 (directAnnotation).
CNTNAP3B	swissregulon__hs__CHD1	CHD1 (directAnnotation).
CNTNAP3B	hdpi__HIP2	UBE2K (directAnnotation).
CNTNAP3B	taipale_tf_pairs__GCM1_SPDEF_RTGNKGGCGGAWG_CAP_repr	GCM1; SPDEF (directAnnotation).
CNTNAP3B	metacluster_170.2	KLF1; KLF10; KLF10; KLF11; KLF11; KLF11; KLF12; KLF12; KLF14; KLF15; KLF17; KLF2; KLF5; KLF7; KLF7; KLF8; MAZ; MAZ; PATZ1; SP1; SP1; SP1; SP2; SP2; SP2; SP2; SP2; SP2; SP2; SP2; SP4; SP4; SP5; SP6; SP7; SP8; SP9; ZNF281 (directAnnotation). E2F1; E2F4; KLF10; KLF13; KLF14; KLF17; KLF2; KLF7; SP1; SP1; SP3; SP4; SP5; SP6; SP7 (inferredBy_Orthology).
CNTNAP3B	transfac_pro__M04893	TAF1 (directAnnotation).
CNTNAP3B	transfac_pro__M03876	ZBTB33 (directAnnotation).
CNTNAP3B	metacluster_15.2	E2F1; E2F1; E2F1; E2F1; E2F1; E2F3; E2F4; E2F4; E2F4; E2F6; E2F6; E2F6; E2F6; E2F6; E2F6; E2F6; E2F7; TFDP1; TFDP2; ZNF566; ZNF566; ZNF574 (directAnnotation). E2F3; E2F3; E2F4 (inferredBy_Orthology).
CNTNAP3B	metacluster_133.1	ZNF304; ZNF304; ZSCAN22 (directAnnotation).
CNTNAP3B	kznf__ZNF441_Imbeault2017_RP_RCADE	ZNF441 (directAnnotation).
CNTNAP3B	transfac_pro__M01219	SP1 (directAnnotation). SP3 (inferredBy_Orthology).
CNTNAP3B	metacluster_3.7	SP1; SP1; SP1; SP1; SP1; SP1; SP1; SP1; SP2; SP2; SP2; SP2; SP3; SP3; SP3; SP4; SP4; SP4; SP4; SP4; SP4; SP5 (directAnnotation).

Page: 1

Top

Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

Top

Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."