Home

Download

Statistics

Landscape

Help

Contact

	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: CNNM1

Summary for CNNM1

Gene information	Gene symbol	CNNM1
	Ensembl ID	ENSG00000119946
	Entrez ID	26507
	Gene name	cyclin and CBS domain divalent metal cation transport mediator 1
	Synonyms	ACDP1
	Gene type	protein_coding
	UniProtAcc	NA

Top

Dataset with differentially expressed gene: CNNM1

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	-1.09496	1.97e-03

Top

Expression of CNNM1 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

Top

Significant ligand-receptor pairs related to CNNM1

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

Top

Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

Top

MicroRNAs (miRNA) regulating CNNM1

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
CNNM1	hsa-miR-6785-5p	96.7719	NM_020348
CNNM1	hsa-miR-4728-5p	95.6435	NM_020348
CNNM1	hsa-miR-6883-5p	95.3329	NM_020348
CNNM1	hsa-miR-149-3p	94.7052	NM_020348
CNNM1	hsa-miR-3152-3p	90.0162	NM_020348
CNNM1	hsa-miR-6782-5p	89.5773	NM_020348
CNNM1	hsa-miR-6772-5p	88.6172	NM_020348
CNNM1	hsa-miR-450b-5p	88.3228	NM_020348
CNNM1	hsa-miR-7110-5p	88.1404	NM_020348
CNNM1	hsa-miR-552-5p	87.4192	NM_020348
CNNM1	hsa-miR-1237-3p	85.8325	NM_020348
CNNM1	hsa-miR-186-3p	85.3997	NM_020348
CNNM1	hsa-miR-6842-5p	85.1377	NM_020348
CNNM1	hsa-miR-4303	84.7558	NM_020348
CNNM1	hsa-miR-6823-3p	84.3023	NM_020348
CNNM1	hsa-miR-6817-5p	83.9783	NM_020348
CNNM1	hsa-miR-4769-3p	83.9783	NM_020348
CNNM1	hsa-miR-4447	83.2902	NM_020348
CNNM1	hsa-miR-3148	82.9689	NM_020348
CNNM1	hsa-miR-6773-3p	82.2933	NM_020348
CNNM1	hsa-miR-4456	81.3218	NM_020348
CNNM1	hsa-miR-4455	81.3114	NM_020348
CNNM1	hsa-miR-3657	81.3082	NM_020348
CNNM1	hsa-miR-5681a	81.1078	NM_020348
CNNM1	hsa-miR-6752-5p	80.9906	NM_020348

Page: 1

Top

Motifs and transcription factors (TFs) regulating CNNM1

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Top

Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

Top

Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."