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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: CFAP20

Summary for CFAP20

Gene information	Gene symbol	CFAP20
	Ensembl ID	ENSG00000070761
	Entrez ID	29105
	Gene name	cilia and flagella associated protein 20
	Synonyms	C16orf80\|fSAP23\|GTL3
	Gene type	protein_coding
	UniProtAcc	Q9Y6A4

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Dataset with differentially expressed gene: CFAP20

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE153697	patients	Bone marrow aspirate	Acute lymphoblastic leukemia	Relapsed B-cell acute lymphoblastic leukemia (B-ALL)	Immunotherapy	anti-CD19 CAR-T	NA	Malignant cells	0.334083	1.34e-21

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Expression of CFAP20 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to CFAP20

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating CFAP20

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
CFAP20	hsa-miR-3163	95.6225	NM_013242
CFAP20	hsa-miR-6508-3p	91.6224	NM_013242
CFAP20	hsa-miR-1277-5p	90.9359	NM_013242
CFAP20	hsa-miR-3180-5p	87.7067	NM_013242
CFAP20	hsa-miR-410-3p	86.4262	NM_013242
CFAP20	hsa-miR-6886-5p	83.9447	NM_013242
CFAP20	hsa-miR-4778-5p	83.1668	NM_013242
CFAP20	hsa-miR-577	82.5839	NM_013242
CFAP20	hsa-miR-12123	80.9276	NM_013242

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Motifs and transcription factors (TFs) regulating CFAP20

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
CFAP20	hdpi__TP73	TP73 (directAnnotation).
CFAP20	transfac_pro__M04944	GABPA (directAnnotation).
CFAP20	transfac_pro__M01182	HINFP (directAnnotation).
CFAP20	cisbp__M02645	ETS1 (directAnnotation).
CFAP20	taipale_tf_pairs__ELF2_NATGCGGAAGTR_HT	ELF2 (directAnnotation).
CFAP20	hdpi__ETV4	ETV4 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."