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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: CEP44

Summary for CEP44

Gene information	Gene symbol	CEP44
	Ensembl ID	ENSG00000164118
	Entrez ID	80817
	Gene name	centrosomal protein 44
	Synonyms	KIAA1712
	Gene type	protein_coding
	UniProtAcc	Q9C0F1

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Dataset with differentially expressed gene: CEP44

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE115251	Kelly cell line	Cell line	Neuroblastoma	Neuroblastoma	Targeted therapy	TAE684	NA	Malignant cells	-0.303005	0.00e+00

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Expression of CEP44 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to CEP44

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating CEP44

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
CEP44	hsa-miR-4775	96.1213	NM_001040157
CEP44	hsa-miR-4633-5p	95.3228	NM_001145314
CEP44	hsa-miR-15b-3p	94.4164	NM_001145314
CEP44	hsa-miR-4793-3p	94.2459	NM_001040157
CEP44	hsa-miR-1299	94.0587	NM_001145314
CEP44	hsa-miR-875-3p	93.8371	NM_001145314
CEP44	hsa-miR-4666a-3p	93.8077	NM_001040157
CEP44	hsa-miR-2114-5p	93.4163	NM_001040157
CEP44	hsa-miR-374c-3p	92.3961	NM_001040157
CEP44	hsa-miR-630	92.3759	NM_001040157
CEP44	hsa-miR-6742-3p	92.3128	NM_001040157
CEP44	hsa-miR-656-3p	92.1042	NM_001040157
CEP44	hsa-miR-10393-5p	90.1892	NM_001040157
CEP44	hsa-miR-4760-3p	90.0615	NM_001040157
CEP44	hsa-miR-3152-3p	89.9617	NM_001145314
CEP44	hsa-miR-548az-5p	89.8792	NM_001040157
CEP44	hsa-miR-548t-5p	89.8792	NM_001040157
CEP44	hsa-miR-338-5p	88.8777	NM_001040157
CEP44	hsa-miR-5706	88.2829	NM_001145314
CEP44	hsa-miR-4782-5p	88.2829	NM_001145314
CEP44	hsa-miR-6516-5p	88.0435	NM_001040157
CEP44	hsa-miR-215-3p	87.4164	NM_001145314
CEP44	hsa-miR-4743-3p	86.6874	NM_001145314
CEP44	hsa-miR-6755-3p	86.6035	NM_001145314
CEP44	hsa-miR-141-5p	86.2256	NM_001040157
CEP44	hsa-miR-6853-3p	84.2234	NM_001040157
CEP44	hsa-miR-3619-5p	82.9651	NM_001145314
CEP44	hsa-miR-214-3p	82.9219	NM_001145314
CEP44	hsa-miR-761	82.9219	NM_001145314
CEP44	hsa-miR-3609	82.7268	NM_001145314
CEP44	hsa-miR-548ah-5p	82.7268	NM_001145314
CEP44	hsa-miR-30d-3p	82.7027	NM_001145314
CEP44	hsa-miR-30e-3p	82.7027	NM_001145314
CEP44	hsa-miR-30a-3p	82.7027	NM_001145314
CEP44	hsa-miR-4712-3p	82.5851	NM_001040157
CEP44	hsa-miR-499a-3p	82.2334	NM_001040157
CEP44	hsa-miR-499b-3p	82.2334	NM_001040157
CEP44	hsa-miR-4999-5p	82.2257	NM_001145314
CEP44	hsa-miR-6730-3p	81.7984	NM_001145314
CEP44	hsa-miR-4475	81.7676	NM_001145314
CEP44	hsa-miR-340-5p	81.5382	NM_001040157
CEP44	hsa-miR-3919	81.3836	NM_001145314
CEP44	hsa-miR-3658	81.1403	NM_001040157
CEP44	hsa-miR-3924	80.6871	NM_001040157

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Motifs and transcription factors (TFs) regulating CEP44

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
CEP44	hocomoco__MNX1_HUMAN.H11MO.0.D	MNX1 (directAnnotation).
CEP44	hocomoco__TYY2_HUMAN.H11MO.0.D	YY2 (directAnnotation).
CEP44	transfac_pro__M02843	BBX (inferredBy_Orthology).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."