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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: CCDC82

Summary for CCDC82

Gene information	Gene symbol	CCDC82
	Ensembl ID	ENSG00000149231
	Entrez ID	79780
	Gene name	coiled-coil domain containing 82
	Synonyms	FLJ23518
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: CCDC82

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE139386	H3122 cell line	Cell line	Lung cancer	EML4-ALK fusion-positive non-small cell lung cancer (NSCLC)	Targeted therapy	ceritinib	NA	Malignant cells	-0.526814	0.00e+00

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Expression of CCDC82 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to CCDC82

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating CCDC82

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
CCDC82	hsa-miR-5011-5p	99.045	NM_001318737
CCDC82	hsa-miR-190a-3p	97.1637	NM_001318737
CCDC82	hsa-miR-577	95.9855	NM_001318736
CCDC82	hsa-miR-5003-3p	94.6334	NM_001318737
CCDC82	hsa-miR-2110	94.626	NM_001318737
CCDC82	hsa-miR-541-5p	91.9285	NM_001318737
CCDC82	hsa-miR-4668-5p	91.852	NM_001318736
CCDC82	hsa-miR-3646	91.5321	NM_001318737
CCDC82	hsa-miR-195-3p	91.2264	NM_001318737
CCDC82	hsa-miR-16-2-3p	91.2264	NM_001318737
CCDC82	hsa-miR-548c-3p	90.9791	NM_001318736
CCDC82	hsa-miR-450a-2-3p	90.8512	NM_001318737
CCDC82	hsa-miR-4659b-5p	90.3911	NM_001318736
CCDC82	hsa-miR-8076	90.3084	NM_001318736
CCDC82	hsa-miR-548e-5p	89.8239	NM_001318737
CCDC82	hsa-miR-6815-3p	89.1379	NM_001318737
CCDC82	hsa-miR-203b-3p	89.105	NM_001318736
CCDC82	hsa-miR-4316	88.6769	NM_001318737
CCDC82	hsa-miR-4729	88.6051	NM_001318737
CCDC82	hsa-miR-4659a-5p	88.5967	NM_001318736
CCDC82	hsa-miR-513a-5p	88.0409	NM_001318736
CCDC82	hsa-miR-1297	87.8887	NM_001318737
CCDC82	hsa-miR-510-3p	86.7117	NM_001318737
CCDC82	hsa-miR-335-3p	86.2713	NM_001318737
CCDC82	hsa-miR-26a-5p	86.0676	NM_001318737
CCDC82	hsa-miR-26b-5p	86.0676	NM_001318737
CCDC82	hsa-miR-200b-3p	85.8169	NM_001318736
CCDC82	hsa-miR-429	85.8169	NM_001318736
CCDC82	hsa-miR-200c-3p	85.8169	NM_001318736
CCDC82	hsa-miR-4465	85.7765	NM_001318737
CCDC82	hsa-miR-1261	85.7507	NM_001318736
CCDC82	hsa-miR-4750-3p	85.64	NM_001318736
CCDC82	hsa-miR-1250-3p	85.5291	NM_001318737
CCDC82	hsa-miR-5585-3p	85.3995	NM_001318736
CCDC82	hsa-miR-6855-5p	84.1777	NM_001318737
CCDC82	hsa-miR-338-5p	83.1636	NM_001318736
CCDC82	hsa-miR-3163	83.1227	NM_001318736
CCDC82	hsa-miR-3133	82.8689	NM_001318737
CCDC82	hsa-miR-4519	82.4537	NM_001318737
CCDC82	hsa-miR-3170	81.2081	NM_001318737
CCDC82	hsa-miR-410-3p	80.7621	NM_001318736
CCDC82	hsa-miR-5696	80.2208	NM_001318737

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Motifs and transcription factors (TFs) regulating CCDC82

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
CCDC82	metacluster_191.2	ELK4; NR2C2; NR2C2; NR2C2; NR2C2 (directAnnotation). GABPA (inferredBy_Orthology).
CCDC82	dbtfbs__E2F8_representative_N1	E2F8 (directAnnotation).
CCDC82	metacluster_15.3	E2F1; E2F6; E2F8; E2F8; TFDP1 (directAnnotation). E2F3 (inferredBy_Orthology).
CCDC82	metacluster_191.3	EHF; ELF1; ELF1; ELF1; ELF4; ELK1; ELK3; ELK3; ELK4; ELK4; ERF; ETS1; ETS2; ETV3; ETV4; ETV5; FEV; FEV; FLI1; FLI1; GABPA; GABPA; GABPA; GABPA; GABPA; GABPA; SPDEF; ZNF200 (directAnnotation). ELK1; ELK1; ELK3; ELK3; ELK4; ELK4; ETV1; ETV1; ETV4; ETV4; ETV4; ETV5; GABPA; GABPA (inferredBy_Orthology).
CCDC82	taipale_cyt_meth__ZNF385D_NCGTCGCGACGN_eDBD_meth	ZNF385D (directAnnotation).
CCDC82	taipale_tf_pairs__ELK1_EOMES_RSCGGAANNAGGYGYNA_CAP_repr	ELK1; EOMES (directAnnotation).
CCDC82	taipale_tf_pairs__ERF_HES7_NNCACGTGNNNNCCGGAANN_CAP_repr	ERF; HES7 (directAnnotation).
CCDC82	metacluster_197.2	E2F4; E2F7; E2F7; E2F7; E2F8; E2F8 (directAnnotation).
CCDC82	cisbp__M08198	ELF1 (directAnnotation).
CCDC82	transfac_pro__M00652	NRF1 (directAnnotation).
CCDC82	hdpi__ETV4	ETV4 (directAnnotation).
CCDC82	transfac_pro__M04866	HDAC2 (directAnnotation).
CCDC82	jaspar__MA1122.1	TFDP1 (directAnnotation).
CCDC82	metacluster_166.4	BCLAF1; EHF; ELF1; ELF1; ELF1; ELF1; ELF1; ELF1; ELF2; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK3; ELK3; ELK3; ELK3; ELK4; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS1; ETS1; ETS1; ETV1; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV4; ETV4; ETV4; ETV4; ETV5; ETV7; FEV; FEV; FLI1; FLI1; FLI1; FLI1; GABPA; GABPA; GABPA; GABPA; GABPA; GABPA; GABPB1; GATAD1; PHF20; ZBTB25; ZBTB40 (directAnnotation). EHF; ELF1; ELF1; ELF3; ELF5; ELK3; ELK4; ERG; ETS1; ETV1; ETV2; ETV4; FLI1; GABPA; GABPA (inferredBy_Orthology).
CCDC82	swissregulon__hs__ZBTB14	ZBTB14 (directAnnotation).
CCDC82	metacluster_138.2	ELF1; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK3; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ERF; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS2; ETS2; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV5; ETV5; FEV; FLI1; FLI1; GABPA; GABPA; KMT2B; SPDEF; SPDEF; SPDEF; ZBTB11; ZNF518A; ZNF580 (directAnnotation). ELF1; ELF2; ELF4; ELK1; ELK1; ELK3; ELK4; ERG; ETS1; ETS2; ETV1; ETV2; ETV3; ETV4; ETV5; FEV; FLI1; FLI1; GABPA; SPDEF; SPDEF (inferredBy_Orthology).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."