Home

Download

Statistics

Landscape

Help

Contact

	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: CCDC40

Summary for CCDC40

Gene information	Gene symbol	CCDC40
	Ensembl ID	ENSG00000141519
	Entrez ID	55036
	Gene name	coiled-coil domain containing 40
	Synonyms	CFAP172\|CILD15\|FAP172\|FLJ20753\|FLJ32021\|KIAA1640
	Gene type	protein_coding
	UniProtAcc	Q4G0X9

Top

Dataset with differentially expressed gene: CCDC40

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	-0.732819	1.75e-03

Top

Expression of CCDC40 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

Top

Significant ligand-receptor pairs related to CCDC40

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

Top

Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

Top

MicroRNAs (miRNA) regulating CCDC40

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
CCDC40	hsa-miR-892c-5p	93.6429	NM_017950
CCDC40	hsa-miR-4534	93.5419	NM_017950
CCDC40	hsa-miR-8082	92.4325	NM_017950
CCDC40	hsa-miR-6071	91.6632	NM_017950
CCDC40	hsa-miR-5008-5p	91.1929	NM_001243342
CCDC40	hsa-miR-548an	90.2517	NM_001243342
CCDC40	hsa-miR-548av-3p	89.1559	NM_017950
CCDC40	hsa-miR-6867-5p	88.7616	NM_001243342
CCDC40	hsa-miR-6808-3p	87.6677	NM_001243342
CCDC40	hsa-miR-6767-3p	87.6552	NM_001243342
CCDC40	hsa-miR-28-3p	87.0638	NM_017950
CCDC40	hsa-miR-93-3p	85.8943	NM_017950
CCDC40	hsa-miR-582-3p	84.2494	NM_017950
CCDC40	hsa-miR-4446-5p	83.0794	NM_017950
CCDC40	hsa-miR-6793-5p	82.6808	NM_017950
CCDC40	hsa-miR-6886-3p	81.5686	NM_017950
CCDC40	hsa-miR-4531	81.516	NM_017950

Page: 1

Top

Motifs and transcription factors (TFs) regulating CCDC40

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Top

Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

Top

Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."