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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: CCDC102B

Summary for CCDC102B

Gene information	Gene symbol	CCDC102B
	Ensembl ID	ENSG00000150636
	Entrez ID	79839
	Gene name	coiled-coil domain containing 102B
	Synonyms	ACY1L\|AN\|C18orf14\|FLJ23594\|HsT1731
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: CCDC102B

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE164897_VemTra	A375 cell line	Cell line	Melanoma	B+E2:E57RAFV600E-mutant melanoma	Targeted therapy	vemurafenib + trametinib	NA	Malignant cells	0.571893	0.00e+00

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Expression of CCDC102B in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to CCDC102B

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating CCDC102B

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
CCDC102B	hsa-miR-3688-3p	94.9328	NM_001093729
CCDC102B	hsa-miR-488-5p	93.004	NM_001093729
CCDC102B	hsa-miR-3658	90.5889	NM_001093729
CCDC102B	hsa-miR-5680	90.0659	NM_001093729
CCDC102B	hsa-miR-511-5p	88.9607	NM_001093729
CCDC102B	hsa-miR-6857-3p	86.3588	NM_001093729
CCDC102B	hsa-let-7f-1-3p	86.2978	NM_001093729
CCDC102B	hsa-let-7a-3p	86.2978	NM_001093729
CCDC102B	hsa-miR-98-3p	86.2978	NM_001093729
CCDC102B	hsa-let-7b-3p	86.2978	NM_001093729
CCDC102B	hsa-miR-153-5p	85.6609	NM_001093729
CCDC102B	hsa-miR-580-3p	85.399	NM_001093729
CCDC102B	hsa-miR-3163	84.9453	NM_001093729
CCDC102B	hsa-miR-548x-3p	84.5147	NM_001093729
CCDC102B	hsa-miR-548aj-3p	84.5147	NM_001093729
CCDC102B	hsa-miR-3942-3p	83.8807	NM_001093729
CCDC102B	hsa-miR-4723-5p	82.0752	NM_001093729
CCDC102B	hsa-miR-6870-5p	82.0752	NM_001093729
CCDC102B	hsa-miR-5698	82.0752	NM_001093729
CCDC102B	hsa-miR-7111-5p	82.0752	NM_001093729
CCDC102B	hsa-miR-4495	81.238	NM_001093729

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Motifs and transcription factors (TFs) regulating CCDC102B

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
CCDC102B	hdpi__TP73	TP73 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."