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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: CAMSAP2

Summary for CAMSAP2

Gene information	Gene symbol	CAMSAP2
	Ensembl ID	ENSG00000118200
	Entrez ID	23271
	Gene name	calmodulin regulated spectrin associated protein family member 2
	Synonyms	CAMSAP1L1\|KIAA1078
	Gene type	protein_coding
	UniProtAcc	Q08AD1

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Dataset with differentially expressed gene: CAMSAP2

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE186960	Panc1 cell line	Cell line	Pancreatic cancer	Pancreatic ductal adenocarcinoma (PDAC)	Chemotherapy	gemcitabine	NA	Malignant cells	-0.42412	3.36e-32

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Expression of CAMSAP2 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to CAMSAP2

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating CAMSAP2

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
CAMSAP2	hsa-miR-182-5p	99.5901	NM_001297707
CAMSAP2	hsa-miR-5195-3p	98.7621	NM_001297707
CAMSAP2	hsa-miR-4789-5p	98.6767	NM_001297707
CAMSAP2	hsa-miR-499b-5p	98.3479	NM_001297707
CAMSAP2	hsa-miR-145-5p	98.1073	NM_001297707
CAMSAP2	hsa-miR-7-2-3p	98.0143	NM_001297707
CAMSAP2	hsa-miR-7-1-3p	98.0143	NM_001297707
CAMSAP2	hsa-miR-4719	97.9932	NM_001297708
CAMSAP2	hsa-miR-6808-5p	97.1136	NM_001297707
CAMSAP2	hsa-miR-6893-5p	97.1136	NM_001297707
CAMSAP2	hsa-miR-940	97.1136	NM_001297707
CAMSAP2	hsa-miR-590-3p	97.0378	NM_001297707
CAMSAP2	hsa-miR-6868-3p	96.4866	NM_001297708
CAMSAP2	hsa-miR-4803	96.4355	NM_001297707
CAMSAP2	hsa-miR-4789-3p	96.0942	NM_001297707
CAMSAP2	hsa-miR-1910-3p	95.8667	NM_001297707
CAMSAP2	hsa-miR-449c-5p	95.6722	NM_001297707
CAMSAP2	hsa-miR-34b-5p	95.6722	NM_001297707
CAMSAP2	hsa-miR-3133	95.6124	NM_001297707
CAMSAP2	hsa-miR-4328	95.2728	NM_001297707
CAMSAP2	hsa-miR-6511a-5p	94.8193	NM_001297707
CAMSAP2	hsa-miR-2682-5p	94.8193	NM_001297707
CAMSAP2	hsa-miR-580-3p	93.1582	NM_001297707
CAMSAP2	hsa-miR-4470	93.0955	NM_001297707
CAMSAP2	hsa-miR-374b-5p	92.851	NM_001297708
CAMSAP2	hsa-miR-1264	92.617	NM_001297707
CAMSAP2	hsa-miR-548m	92.3913	NM_001297708
CAMSAP2	hsa-miR-374a-5p	92.2463	NM_001297708
CAMSAP2	hsa-miR-21-3p	91.9287	NM_001297708
CAMSAP2	hsa-miR-122b-3p	91.9287	NM_001297708
CAMSAP2	hsa-miR-3682-5p	91.6948	NM_001297708
CAMSAP2	hsa-miR-582-5p	91.66	NM_001297708
CAMSAP2	hsa-miR-1200	91.3828	NM_001297707
CAMSAP2	hsa-miR-3662	91.3776	NM_001297707
CAMSAP2	hsa-miR-4775	91.0085	NM_001297708
CAMSAP2	hsa-miR-4795-5p	90.9861	NM_001297707
CAMSAP2	hsa-miR-4771	90.5328	NM_001297707
CAMSAP2	hsa-miR-429	90.4386	NM_001297707
CAMSAP2	hsa-miR-200c-3p	90.4386	NM_001297707
CAMSAP2	hsa-miR-200b-3p	90.4386	NM_001297707
CAMSAP2	hsa-miR-12123	90.0253	NM_001297707
CAMSAP2	hsa-miR-6502-5p	90.0144	NM_001297707
CAMSAP2	hsa-miR-1301-5p	90.0144	NM_001297707
CAMSAP2	hsa-miR-101-5p	89.73	NM_001297708
CAMSAP2	hsa-miR-548ag	89.557	NM_001297707
CAMSAP2	hsa-miR-570-5p	89.557	NM_001297707
CAMSAP2	hsa-miR-548ba	89.557	NM_001297707
CAMSAP2	hsa-miR-548ai	89.557	NM_001297707
CAMSAP2	hsa-miR-559	89.4447	NM_001297707
CAMSAP2	hsa-miR-132-3p	89.3913	NM_001297707

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Motifs and transcription factors (TFs) regulating CAMSAP2

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
CAMSAP2	taipale_tf_pairs__ETV5_HOXA2_RSCGGWAATKR_CAP	ETV5; HOXA2 (directAnnotation).
CAMSAP2	metacluster_138.2	ELF1; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK3; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ERF; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS2; ETS2; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV5; ETV5; FEV; FLI1; FLI1; GABPA; GABPA; KMT2B; SPDEF; SPDEF; SPDEF; ZBTB11; ZNF518A; ZNF580 (directAnnotation). ELF1; ELF2; ELF4; ELK1; ELK1; ELK3; ELK4; ERG; ETS1; ETS2; ETV1; ETV2; ETV3; ETV4; ETV5; FEV; FLI1; FLI1; GABPA; SPDEF; SPDEF (inferredBy_Orthology).
CAMSAP2	metacluster_33.8	BRCA1; CHD2; CHD2; ETS1; NR3C1; ZBED1; ZBED1; ZBED1; ZBTB33; ZBTB33; ZBTB33; ZBTB33; ZBTB33; ZBTB33; ZBTB33 (directAnnotation). CHD2; ZBTB33 (inferredBy_Orthology).
CAMSAP2	metacluster_141.6	MZF1; TAF1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY2; YY2; ZFP42; ZFP42; ZFP42; ZFP42; ZFP42; ZFP42; ZNF597 (directAnnotation). TAF1; TAF1L (inferredBy_Orthology).
CAMSAP2	taipale_tf_pairs__ETV5_EVX1_RSCGGWAATKR_CAP	ETV5; EVX1 (directAnnotation).
CAMSAP2	taipale_tf_pairs__E2F1_ELK1_SGCGCNNNNNCGGAAGN_CAP_repr	E2F1; ELK1 (directAnnotation).
CAMSAP2	taipale_tf_pairs__FOXO1_ETV1_RCCGGAWGTKKN_CAP	ETV1; FOXO1 (directAnnotation).
CAMSAP2	jaspar__MA0748.2	YY2 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."