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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: C1orf210

Summary for C1orf210

Gene information	Gene symbol	C1orf210
	Ensembl ID	ENSG00000253313
	Entrez ID	149466
	Gene name	chromosome 1 open reading frame 210
	Synonyms	MGC52423\|TEMP
	Gene type	protein_coding
	UniProtAcc	Q8IVY1

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Dataset with differentially expressed gene: C1orf210

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE163836	FCIBC02 cell line	Cell line	Breast cancer	Inflammatory breast cancer	Chemotherapy	paclitaxel	NA	Malignant cells	-0.331635	0.00e+00

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Expression of C1orf210 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to C1orf210

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating C1orf210

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
C1orf210	hsa-miR-4698	91.6761	NM_182517
C1orf210	hsa-miR-1285-3p	90.8677	NM_182517
C1orf210	hsa-miR-3148	88.3738	NM_182517
C1orf210	hsa-miR-5189-5p	88.0997	NM_182517
C1orf210	hsa-miR-1249-5p	86.5429	NM_182517
C1orf210	hsa-miR-6797-5p	86.5429	NM_182517
C1orf210	hsa-miR-3187-5p	86.4603	NM_182517
C1orf210	hsa-miR-612	86.2086	NM_182517
C1orf210	hsa-miR-6860	86.2086	NM_182517
C1orf210	hsa-miR-4319	86.011	NM_001164829
C1orf210	hsa-miR-3664-3p	84.4813	NM_182517
C1orf210	hsa-miR-6785-5p	83.683	NM_182517
C1orf210	hsa-miR-4728-5p	83.683	NM_182517
C1orf210	hsa-miR-544b	81.7321	NM_001164829
C1orf210	hsa-miR-6883-5p	81.1111	NM_182517
C1orf210	hsa-miR-149-3p	81.1111	NM_182517
C1orf210	hsa-miR-125b-5p	80.8608	NM_001164829
C1orf210	hsa-miR-125a-5p	80.8608	NM_001164829

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Motifs and transcription factors (TFs) regulating C1orf210

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
C1orf210	taipale_tf_pairs__ELK1_FOXI1_RSCGGATGTKKN_CAP	ELK1; FOXI1 (directAnnotation).
C1orf210	taipale_tf_pairs__ERF_FOXI1_RSCGGATGTTKWN_CAP_repr	ERF; FOXI1 (directAnnotation).
C1orf210	taipale_tf_pairs__ETV2_FOXO6_RCCGGATGTTKWN_CAP	ETV2; FOXO6 (directAnnotation).
C1orf210	taipale_tf_pairs__ETV2_DLX3_RSCGGAANNNNNNNTAATKR_CAP_repr	DLX3; ETV2 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."