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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: BAIAP2

Summary for BAIAP2

Gene information	Gene symbol	BAIAP2
	Ensembl ID	ENSG00000175866
	Entrez ID	10458
	Gene name	BAR/IMD domain containing adaptor protein 2
	Synonyms	BAP2\|IRSp53\|WAML
	Gene type	protein_coding
	UniProtAcc	Q9UQB8

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Dataset with differentially expressed gene: BAIAP2

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE139386	H3122 cell line	Cell line	Lung cancer	EML4-ALK fusion-positive non-small cell lung cancer (NSCLC)	Targeted therapy	ceritinib	NA	Malignant cells	-0.520738	0.00e+00

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Expression of BAIAP2 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to BAIAP2

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating BAIAP2

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
BAIAP2	hsa-miR-744-3p	95.9915	NM_006340
BAIAP2	hsa-miR-6501-5p	93.5585	NM_006340
BAIAP2	hsa-miR-4722-5p	93.5003	NM_001144888
BAIAP2	hsa-miR-331-3p	92.0723	NM_017450
BAIAP2	hsa-miR-5582-3p	90.8079	NM_017450
BAIAP2	hsa-miR-1207-3p	90.0835	NM_006340
BAIAP2	hsa-miR-5688	89.8011	NM_017451
BAIAP2	hsa-miR-561-3p	88.8531	NM_017451
BAIAP2	hsa-miR-495-3p	88.6042	NM_017451
BAIAP2	hsa-miR-3148	85.29	NM_017450
BAIAP2	hsa-miR-1304-5p	84.3951	NM_017451
BAIAP2	hsa-miR-767-3p	84.3329	NM_017450
BAIAP2	hsa-miR-5010-3p	84.0902	NM_017451
BAIAP2	hsa-miR-497-3p	83.1554	NM_017450
BAIAP2	hsa-miR-940	82.4438	NM_001144888
BAIAP2	hsa-miR-6893-5p	82.4438	NM_001144888
BAIAP2	hsa-miR-6808-5p	82.4438	NM_001144888
BAIAP2	hsa-miR-6124	81.1093	NM_017450

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Motifs and transcription factors (TFs) regulating BAIAP2

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
BAIAP2	metacluster_191.2	ELK4; NR2C2; NR2C2; NR2C2; NR2C2 (directAnnotation). GABPA (inferredBy_Orthology).
BAIAP2	taipale_cyt_meth__ZNF385D_NCGTCGCGACGN_eDBD_meth	ZNF385D (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."