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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: BAHCC1

Summary for BAHCC1

Gene information	Gene symbol	BAHCC1
	Ensembl ID	ENSG00000266074
	Entrez ID	57597
	Gene name	BAH domain and coiled-coil containing 1
	Synonyms	BAHD2\|KIAA1447
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: BAHCC1

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE199333	patients	Bone marrow aspirate	Acute myeloid leukemia	Primary FLT3-ITD-mutated acute myeloid leukemia (AML)	Targeted therapy	gilteritinib	pre	Malignant cells	-0.510506	0.00e+00
GSE175716	PDX	Tumor tissue	Liver cancer	Advanced hepatocellular carcinoma	Targeted therapy	sorafenib	NA	Malignant cells	-0.499036	1.14e-42

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Expression of BAHCC1 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to BAHCC1

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating BAHCC1

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
BAHCC1	hsa-miR-376c-3p	97.3896	NM_001291324
BAHCC1	hsa-miR-338-5p	93.2979	NM_001291324
BAHCC1	hsa-miR-7703	92.7423	NM_001291324
BAHCC1	hsa-miR-548as-3p	92.1051	NM_001291324
BAHCC1	hsa-miR-3622a-3p	91.9471	NM_001291324
BAHCC1	hsa-miR-3622b-3p	91.9471	NM_001291324
BAHCC1	hsa-miR-466	91.6948	NM_001291324
BAHCC1	hsa-miR-548at-3p	90.9181	NM_001291324
BAHCC1	hsa-miR-548ay-3p	90.9181	NM_001291324
BAHCC1	hsa-miR-95-5p	90.9102	NM_001291324
BAHCC1	hsa-miR-101-5p	90.4074	NM_001291324
BAHCC1	hsa-miR-16-2-3p	90.0468	NM_001291324
BAHCC1	hsa-miR-195-3p	90.0468	NM_001291324
BAHCC1	hsa-miR-7113-5p	89.6772	NM_001291324
BAHCC1	hsa-miR-2681-5p	89.6404	NM_001291324
BAHCC1	hsa-miR-6778-5p	89.2931	NM_001291324
BAHCC1	hsa-miR-135a-5p	88.6034	NM_001291324
BAHCC1	hsa-miR-135b-5p	88.6034	NM_001291324
BAHCC1	hsa-miR-6756-5p	88.0925	NM_001291324
BAHCC1	hsa-miR-6766-5p	88.0925	NM_001291324
BAHCC1	hsa-miR-548t-3p	87.7683	NM_001291324
BAHCC1	hsa-miR-548aa	87.7683	NM_001291324
BAHCC1	hsa-miR-548ap-3p	87.7683	NM_001291324
BAHCC1	hsa-miR-4456	87.1499	NM_001291324
BAHCC1	hsa-miR-92b-3p	86.9074	NM_001291324
BAHCC1	hsa-miR-92a-3p	86.9074	NM_001291324
BAHCC1	hsa-miR-32-5p	86.9074	NM_001291324
BAHCC1	hsa-miR-122b-5p	86.6254	NM_001291324
BAHCC1	hsa-miR-3680-3p	86.5647	NM_001291324
BAHCC1	hsa-miR-4672	86.1706	NM_001291324
BAHCC1	hsa-miR-3941	86.1706	NM_001291324
BAHCC1	hsa-miR-1275	86.0685	NM_001291324
BAHCC1	hsa-miR-448	86.0497	NM_001291324
BAHCC1	hsa-miR-1233-5p	84.7839	NM_001291324
BAHCC1	hsa-miR-7109-5p	84.7622	NM_001291324
BAHCC1	hsa-miR-4255	82.7269	NM_001291324
BAHCC1	hsa-miR-4325	81.9574	NM_001291324
BAHCC1	hsa-miR-25-3p	81.7295	NM_001291324
BAHCC1	hsa-miR-367-3p	81.7295	NM_001291324
BAHCC1	hsa-miR-363-3p	81.7295	NM_001291324
BAHCC1	hsa-miR-3912-5p	80.0665	NM_001291324

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Motifs and transcription factors (TFs) regulating BAHCC1

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
BAHCC1	metacluster_135.11	NR2C2 (directAnnotation).
BAHCC1	metacluster_135.10	MBD2; MBD2; MECP2; MECP2 (directAnnotation).
BAHCC1	jaspar__MA0185.1	DEAF1 (inferredBy_Orthology).
BAHCC1	transfac_pro__M01122	ZNF219 (directAnnotation).
BAHCC1	kznf__ZNF571_Imbeault2017_OM_RCADE	ZNF571 (directAnnotation).
BAHCC1	kznf__ZNF783_Imbeault2017_OM_MEME	ZNF783 (directAnnotation).
BAHCC1	dbtfbs__ZSCAN30_HEK293_ENCSR768VNZ_merged_N1	ZSCAN30 (directAnnotation).
BAHCC1	tfdimers__MD00151	CHURC1 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."