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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: ATP10D

Summary for ATP10D

Gene information	Gene symbol	ATP10D
	Ensembl ID	ENSG00000145246
	Entrez ID	57205
	Gene name	ATPase phospholipid transporting 10D (putative)
	Synonyms	ATPVD\|KIAA1487
	Gene type	protein_coding
	UniProtAcc	Q9P241

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Dataset with differentially expressed gene: ATP10D

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	1.26305	4.14e-03

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Expression of ATP10D in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to ATP10D

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ATP10D

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
ATP10D	hsa-miR-4263	96.9221	NM_020453
ATP10D	hsa-miR-3127-5p	94.9976	NM_020453
ATP10D	hsa-miR-4319	94.936	NM_020453
ATP10D	hsa-miR-4328	94.4049	NM_020453
ATP10D	hsa-miR-125b-5p	93.8269	NM_020453
ATP10D	hsa-miR-125a-5p	93.098	NM_020453
ATP10D	hsa-miR-607	92.1191	NM_020453
ATP10D	hsa-miR-1185-5p	91.8884	NM_020453
ATP10D	hsa-miR-12128	91.2941	NM_020453
ATP10D	hsa-miR-3679-5p	91.2062	NM_020453
ATP10D	hsa-miR-182-5p	87.8017	NM_020453
ATP10D	hsa-miR-4324	87.7363	NM_020453
ATP10D	hsa-miR-3059-5p	85.0512	NM_020453
ATP10D	hsa-miR-1270	84.977	NM_020453
ATP10D	hsa-miR-587	83.421	NM_020453
ATP10D	hsa-miR-4752	83.09	NM_020453
ATP10D	hsa-miR-6732-3p	82.3125	NM_020453
ATP10D	hsa-miR-520f-5p	81.8646	NM_020453
ATP10D	hsa-miR-1179	81.8144	NM_020453
ATP10D	hsa-miR-212-3p	81.4483	NM_020453
ATP10D	hsa-miR-132-3p	81.4483	NM_020453
ATP10D	hsa-miR-12131	81.3232	NM_020453
ATP10D	hsa-miR-12124	81.1949	NM_020453
ATP10D	hsa-miR-582-5p	81.1313	NM_020453
ATP10D	hsa-miR-3201	80.9762	NM_020453
ATP10D	hsa-miR-205-3p	80.311	NM_020453

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Motifs and transcription factors (TFs) regulating ATP10D

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
ATP10D	kznf__ZNF594_Schmitges2016_RCADE	ZNF594 (directAnnotation).
ATP10D	metacluster_195.2	EGR2; KLF10; KLF10; KLF11; KLF11; KLF11; KLF13; KLF13; KLF13; KLF13; KLF13; KLF14; KLF14; KLF14; KLF14; KLF14; KLF15; KLF15; KLF16; KLF3; KLF8; KLF9; KLF9; KLF9; SP1; SP1; SP1; SP3; SP3; SP4; SP8; SP8; SP8; SP9; SP9 (directAnnotation). EGR1; KLF1; KLF12; KLF13; KLF14; KLF14; KLF14; KLF14; KLF14; KLF14; KLF16; KLF17; KLF17; KLF17; KLF17; KLF18; KLF18; KLF18; KLF18; KLF18; KLF18; KLF2; KLF2; KLF2; KLF3; KLF4; KLF5; KLF5; KLF5; KLF6; KLF7; KLF7; KLF8; KLF9; SP1; SP3; SP4; SP4; SP5; SP5; SP5; SP6; SP7; SP8; SP9 (inferredBy_Orthology).
ATP10D	hdpi__HIP2	UBE2K (directAnnotation).
ATP10D	taipale_tf_pairs__GCM1_SPDEF_RTGNKGGCGGAWG_CAP_repr	GCM1; SPDEF (directAnnotation).
ATP10D	transfac_pro__M04893	TAF1 (directAnnotation).
ATP10D	metacluster_15.2	E2F1; E2F1; E2F1; E2F1; E2F1; E2F3; E2F4; E2F4; E2F4; E2F6; E2F6; E2F6; E2F6; E2F6; E2F6; E2F6; E2F7; TFDP1; TFDP2; ZNF566; ZNF566; ZNF574 (directAnnotation). E2F3; E2F3; E2F4 (inferredBy_Orthology).
ATP10D	kznf__ZNF441_Imbeault2017_RP_RCADE	ZNF441 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."