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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: ARMT1

Summary for ARMT1

Gene information	Gene symbol	ARMT1
	Ensembl ID	ENSG00000146476
	Entrez ID	79624
	Gene name	acidic residue methyltransferase 1
	Synonyms	C6orf211\|FLJ12910
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: ARMT1

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE168668	LNCaP cell line	Cell line	Prostate cancer	Prostate cancer	Targeted therapy	enzalutamide	NA	Malignant cells	0.346367	0.00e+00
GSE104987	MCF7 cell line	Cell line	Breast cancer	ER+ breast cancer	Targeted therapy	KDM5-C70	NA	Malignant cells	-0.315087	1.10e-17

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Expression of ARMT1 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to ARMT1

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ARMT1

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
ARMT1	hsa-miR-3121-3p	96.7212	NM_024573
ARMT1	hsa-miR-664a-3p	95.875	NM_024573
ARMT1	hsa-miR-4795-3p	94.8028	NM_001286562
ARMT1	hsa-miR-664b-3p	94.1566	NM_001286562
ARMT1	hsa-miR-579-3p	94.1566	NM_001286562
ARMT1	hsa-miR-203a-3p	93.0173	NM_024573
ARMT1	hsa-miR-216a-5p	91.7735	NM_024573
ARMT1	hsa-miR-124-5p	91.4958	NM_024573
ARMT1	hsa-miR-548c-3p	88.4028	NM_024573
ARMT1	hsa-miR-5696	87.3454	NM_001286562
ARMT1	hsa-miR-4500	84.1787	NM_001286562
ARMT1	hsa-miR-6507-5p	83.4885	NM_024573
ARMT1	hsa-let-7c-5p	82.7415	NM_001286562
ARMT1	hsa-let-7i-5p	82.7415	NM_001286562
ARMT1	hsa-miR-98-5p	82.7415	NM_001286562
ARMT1	hsa-let-7f-5p	82.7415	NM_001286562
ARMT1	hsa-let-7e-5p	82.7415	NM_001286562
ARMT1	hsa-let-7g-5p	82.7415	NM_001286562
ARMT1	hsa-let-7b-5p	82.7415	NM_001286562
ARMT1	hsa-let-7a-5p	82.7415	NM_001286562
ARMT1	hsa-miR-548e-5p	82.0944	NM_024573
ARMT1	hsa-miR-1825	81.3885	NM_024573
ARMT1	hsa-miR-4699-3p	81.1817	NM_024573
ARMT1	hsa-miR-3145-5p	80.2782	NM_024573
ARMT1	hsa-miR-4458	80.0416	NM_001286562
ARMT1	hsa-miR-202-3p	80.0416	NM_001286562
ARMT1	hsa-let-7d-5p	80.0416	NM_001286562

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Motifs and transcription factors (TFs) regulating ARMT1

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
ARMT1	transfac_pro__M06526	ZNF555 (directAnnotation).
ARMT1	metacluster_14.28	CLOCK (inferredBy_Orthology).
ARMT1	metacluster_57.3	ARNT; ATF3; ATF3; ATF3; ATF3; BHLHE40; BHLHE40; BHLHE40; BHLHE41; BHLHE41; BHLHE41; MITF; MITF; MITF; MLX; MLXIPL; SREBF1; SREBF1; SREBF1; SREBF1; SREBF2; SREBF2; SREBF2; TFE3; TFEC; USF1; USF1; USF1; USF1; USF1; USF1; USF1; USF1; USF1; USF2; USF2; USF2; USF2; USF2; USF2; USF2; USF2; USF2; USF2; USF2; USF2; USF2; ZNF507 (directAnnotation). ARNTL; BHLHE40; BHLHE40; BHLHE41; HELT; HES1; HES2; HES3; HES5; HES6; HES7; HEY1; HEY2; HEYL; MLX; MLX; SREBF1; SREBF2; TFE3; USF1; USF1; USF2; USF2 (inferredBy_Orthology).
ARMT1	transfac_pro__M05427	ZNF516 (directAnnotation).
ARMT1	metacluster_172.6	CHD2; E2F1 (directAnnotation).
ARMT1	transfac_pro__M06141	ZNF708 (directAnnotation).
ARMT1	taipale_cyt_meth__ZNF385D_NCGTCGCGACGN_eDBD_meth	ZNF385D (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."