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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: ABHD13

Summary for ABHD13

Gene information	Gene symbol	ABHD13
	Ensembl ID	ENSG00000139826
	Entrez ID	84945
	Gene name	abhydrolase domain containing 13
	Synonyms	bA153I24.2\|BEM46L1\|C13orf6\|FLJ14906
	Gene type	protein_coding
	UniProtAcc	Q7L211

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Dataset with differentially expressed gene: ABHD13

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE108397	451Lu cell line	Cell line	Melanoma	Melanoma	Targeted therapy	PLX-4720	NA	Malignant cells	0.340318	0.00e+00

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Expression of ABHD13 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to ABHD13

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ABHD13

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
ABHD13	hsa-miR-5011-5p	98.9756	NM_032859
ABHD13	hsa-miR-4282	98.1013	NM_032859
ABHD13	hsa-miR-182-5p	97.536	NM_032859
ABHD13	hsa-miR-548aj-3p	97.5327	NM_032859
ABHD13	hsa-miR-548x-3p	97.5327	NM_032859
ABHD13	hsa-miR-4495	97.3144	NM_032859
ABHD13	hsa-miR-561-5p	97.2628	NM_032859
ABHD13	hsa-miR-3163	97.2484	NM_032859
ABHD13	hsa-miR-548am-3p	97.0583	NM_032859
ABHD13	hsa-miR-548ah-3p	97.0583	NM_032859
ABHD13	hsa-miR-548j-3p	97.0583	NM_032859
ABHD13	hsa-miR-548ae-3p	97.0583	NM_032859
ABHD13	hsa-miR-548aq-3p	97.0583	NM_032859
ABHD13	hsa-miR-4470	96.9502	NM_032859
ABHD13	hsa-miR-4429	95.851	NM_032859
ABHD13	hsa-miR-320b	95.851	NM_032859
ABHD13	hsa-miR-320c	95.851	NM_032859
ABHD13	hsa-miR-320a-3p	95.851	NM_032859
ABHD13	hsa-miR-320d	95.851	NM_032859
ABHD13	hsa-miR-543	95.1475	NM_032859
ABHD13	hsa-miR-374c-5p	95.1187	NM_032859
ABHD13	hsa-miR-655-3p	95.1187	NM_032859
ABHD13	hsa-miR-4433b-5p	95.079	NM_032859
ABHD13	hsa-miR-190a-3p	94.4159	NM_032859
ABHD13	hsa-miR-4659b-5p	94.1222	NM_032859
ABHD13	hsa-miR-4666a-5p	93.5504	NM_032859
ABHD13	hsa-miR-6830-5p	93.5455	NM_032859
ABHD13	hsa-miR-95-5p	92.8559	NM_032859
ABHD13	hsa-miR-7-1-3p	92.8075	NM_032859
ABHD13	hsa-miR-7-2-3p	92.8075	NM_032859
ABHD13	hsa-miR-4659a-5p	92.7649	NM_032859
ABHD13	hsa-miR-4719	92.0694	NM_032859
ABHD13	hsa-miR-3121-3p	91.7482	NM_032859
ABHD13	hsa-miR-3671	90.793	NM_032859
ABHD13	hsa-miR-4646-3p	90.4358	NM_032859
ABHD13	hsa-miR-888-3p	89.9141	NM_032859
ABHD13	hsa-miR-12136	89.8393	NM_032859
ABHD13	hsa-miR-548l	89.2476	NM_032859
ABHD13	hsa-miR-4715-3p	89.2468	NM_032859
ABHD13	hsa-miR-6739-5p	89.1028	NM_032859
ABHD13	hsa-miR-6733-5p	89.1028	NM_032859
ABHD13	hsa-miR-137-3p	88.9037	NM_032859
ABHD13	hsa-miR-1260b	88.7628	NM_032859
ABHD13	hsa-miR-1260a	88.7628	NM_032859
ABHD13	hsa-miR-607	88.6187	NM_032859
ABHD13	hsa-miR-340-5p	88.1425	NM_032859
ABHD13	hsa-miR-4782-3p	87.7366	NM_032859
ABHD13	hsa-miR-6766-3p	87.7366	NM_032859
ABHD13	hsa-miR-219a-5p	87.7366	NM_032859
ABHD13	hsa-miR-513c-3p	87.5287	NM_032859

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Motifs and transcription factors (TFs) regulating ABHD13

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
ABHD13	jaspar__MA1933.1	SREBF2 (directAnnotation).
ABHD13	metacluster_191.2	ELK4; NR2C2; NR2C2; NR2C2; NR2C2 (directAnnotation). GABPA (inferredBy_Orthology).
ABHD13	taipale_tf_pairs__ETS2_RCCGGAAGTG_HT	ETS2 (directAnnotation).
ABHD13	metacluster_166.4	BCLAF1; EHF; ELF1; ELF1; ELF1; ELF1; ELF1; ELF1; ELF2; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK3; ELK3; ELK3; ELK3; ELK4; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS1; ETS1; ETS1; ETV1; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV4; ETV4; ETV4; ETV4; ETV5; ETV7; FEV; FEV; FLI1; FLI1; FLI1; FLI1; GABPA; GABPA; GABPA; GABPA; GABPA; GABPA; GABPB1; GATAD1; PHF20; ZBTB25; ZBTB40 (directAnnotation). EHF; ELF1; ELF1; ELF3; ELF5; ELK3; ELK4; ERG; ETS1; ETV1; ETV2; ETV4; FLI1; GABPA; GABPA (inferredBy_Orthology).
ABHD13	taipale_tf_pairs__MEIS1_ELF1_NTGCCGGAAGTN_CAP_repr	ELF1; MEIS1 (directAnnotation).
ABHD13	metacluster_191.3	EHF; ELF1; ELF1; ELF1; ELF4; ELK1; ELK3; ELK3; ELK4; ELK4; ERF; ETS1; ETS2; ETV3; ETV4; ETV5; FEV; FEV; FLI1; FLI1; GABPA; GABPA; GABPA; GABPA; GABPA; GABPA; SPDEF; ZNF200 (directAnnotation). ELK1; ELK1; ELK3; ELK3; ELK4; ELK4; ETV1; ETV1; ETV4; ETV4; ETV4; ETV5; GABPA; GABPA (inferredBy_Orthology).
ABHD13	taipale_tf_pairs__ELK1_TBX21_TNRCACCGGAAGNN_CAP_repr	ELK1; TBX21 (directAnnotation).
ABHD13	taipale_tf_pairs__ETV5_HOXA2_RSCGGWAATKR_CAP	ETV5; HOXA2 (directAnnotation).
ABHD13	hdpi__ETV4	ETV4 (directAnnotation).
ABHD13	taipale_tf_pairs__ETV5_FOXI1_RSCGGATGTTGN_CAP	ETV5; FOXI1 (directAnnotation).
ABHD13	taipale_tf_pairs__ELK1_TEF_NSCGGAWNTTACGTAAN_CAP	ELK1; TEF (directAnnotation).
ABHD13	cisbp__M02645	ETS1 (directAnnotation).
ABHD13	taipale_tf_pairs__ETV2_HOXA2_NCCGGAAGTMATTA_CAP_repr	ETV2; HOXA2 (directAnnotation).
ABHD13	taipale_tf_pairs__FOXO1_ELK3_RCCGGAWGTKKW_CAP	ELK3; FOXO1 (directAnnotation).
ABHD13	taipale_tf_pairs__ETV5_EOMES_TNRCACCGGAWN_CAP	EOMES; ETV5 (directAnnotation).
ABHD13	metacluster_166.2	ELK4; ETS1; ETS1; ETV1; ETV3; ETV4; ETV5; ETV7 (directAnnotation). GABPA (inferredBy_Orthology).
ABHD13	taipale_tf_pairs__FOXO1_ELK1_TGTTGCCGGANNN_CAP	ELK1; FOXO1 (directAnnotation).
ABHD13	taipale_tf_pairs__ETV2_TCF3_CASSTGNNCCGGAWRYN_CAP_repr	ETV2; TCF3 (directAnnotation).
ABHD13	taipale_tf_pairs__HOXB2_ELK3_RSCGGAAGTMRTTA_CAP	ELK3; HOXB2 (directAnnotation).
ABHD13	taipale_tf_pairs__ELK1_HOXA3_RSCGGTAATKR_CAP_repr	ELK1; HOXA3 (directAnnotation).
ABHD13	taipale_tf_pairs__HOXB2_ETV4_ACCGGAAATGAN_CAP	ETV4; HOXB2 (directAnnotation).
ABHD13	taipale_tf_pairs__ELF2_NATGCGGAAGTR_HT	ELF2 (directAnnotation).
ABHD13	taipale_tf_pairs__ELK1_EOMES_TNRCACCGGAAGN_CAP	ELK1; EOMES (directAnnotation).
ABHD13	taipale_tf_pairs__ELK1_HOXA1_RCCGGAAGTAATTA_HT	ELK1; HOXA1 (directAnnotation).
ABHD13	taipale_tf_pairs__HOXB2_ELF1_SMGGAAGTMRTTA_CAP	ELF1; HOXB2 (directAnnotation).
ABHD13	taipale_tf_pairs__ERF_FOXI1_RSCGGATGTTKWN_CAP_repr	ERF; FOXI1 (directAnnotation).
ABHD13	metacluster_198.7	AHR; ZBTB14; ZBTB14; ZBTB14 (directAnnotation).
ABHD13	taipale_tf_pairs__ERF_HES7_NCCGGAANNNNNNCACGYGNN_CAP_repr	ERF; HES7 (directAnnotation).
ABHD13	metacluster_19.7	GMEB1; GMEB2 (inferredBy_Orthology).
ABHD13	metacluster_138.2	ELF1; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK3; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ERF; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS2; ETS2; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV5; ETV5; FEV; FLI1; FLI1; GABPA; GABPA; KMT2B; SPDEF; SPDEF; SPDEF; ZBTB11; ZNF518A; ZNF580 (directAnnotation). ELF1; ELF2; ELF4; ELK1; ELK1; ELK3; ELK4; ERG; ETS1; ETS2; ETV1; ETV2; ETV3; ETV4; ETV5; FEV; FLI1; FLI1; GABPA; SPDEF; SPDEF (inferredBy_Orthology).
ABHD13	jaspar__MA1957.1	ELK1 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."