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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: ABHD10

Summary for ABHD10

Gene information	Gene symbol	ABHD10
	Ensembl ID	ENSG00000144827
	Entrez ID	55347
	Gene name	abhydrolase domain containing 10, depalmitoylase
	Synonyms	FLJ11342
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: ABHD10

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE168668	LNCaP cell line	Cell line	Prostate cancer	Prostate cancer	Targeted therapy	enzalutamide	NA	Malignant cells	0.355393	0.00e+00

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Expression of ABHD10 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to ABHD10

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ABHD10

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
ABHD10	hsa-miR-656-3p	99.524	NM_018394
ABHD10	hsa-miR-5011-5p	96.9207	NM_018394
ABHD10	hsa-miR-4699-3p	95.9435	NM_001272069
ABHD10	hsa-miR-6888-3p	95.519	NM_018394
ABHD10	hsa-miR-590-3p	93.3875	NM_018394
ABHD10	hsa-miR-5692a	91.3649	NM_018394
ABHD10	hsa-miR-410-3p	90.3618	NM_018394
ABHD10	hsa-miR-190a-3p	89.3942	NM_018394
ABHD10	hsa-miR-6883-3p	88.4315	NM_018394
ABHD10	hsa-miR-4796-5p	87.9235	NM_018394
ABHD10	hsa-miR-1248	87.9067	NM_001272069
ABHD10	hsa-miR-219b-3p	87.5488	NM_018394
ABHD10	hsa-miR-544a	87.3434	NM_018394
ABHD10	hsa-miR-103a-2-5p	86.0605	NM_001272069
ABHD10	hsa-miR-103a-1-5p	86.0605	NM_001272069
ABHD10	hsa-miR-3125	85.963	NM_018394
ABHD10	hsa-miR-3059-5p	85.5914	NM_018394
ABHD10	hsa-miR-6755-3p	85.3715	NM_018394
ABHD10	hsa-miR-2276-3p	84.3586	NM_018394
ABHD10	hsa-miR-142-5p	83.4424	NM_018394
ABHD10	hsa-miR-5590-3p	83.4424	NM_018394
ABHD10	hsa-miR-607	83.1664	NM_018394
ABHD10	hsa-miR-582-5p	83.1559	NM_018394
ABHD10	hsa-miR-30a-5p	82.7676	NM_001272069
ABHD10	hsa-miR-30b-5p	82.7676	NM_001272069
ABHD10	hsa-miR-30d-5p	82.7676	NM_001272069
ABHD10	hsa-miR-30e-5p	82.7676	NM_001272069
ABHD10	hsa-miR-30c-5p	82.7676	NM_001272069
ABHD10	hsa-miR-4314	82.7142	NM_018394
ABHD10	hsa-miR-183-3p	82.2491	NM_018394
ABHD10	hsa-miR-3617-3p	81.9969	NM_018394
ABHD10	hsa-miR-143-5p	81.7193	NM_018394
ABHD10	hsa-miR-1277-5p	81.6389	NM_018394
ABHD10	hsa-miR-4789-5p	81.2389	NM_018394
ABHD10	hsa-miR-486-3p	81.0446	NM_001272069
ABHD10	hsa-miR-34a-3p	80.7258	NM_018394

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Motifs and transcription factors (TFs) regulating ABHD10

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
ABHD10	transfac_pro__M06109	ZNF254 (directAnnotation).
ABHD10	transfac_pro__M06111	ZNF254 (directAnnotation).
ABHD10	metacluster_172.6	CHD2; E2F1 (directAnnotation).
ABHD10	swissregulon__mm__E2f7	E2F7 (inferredBy_Orthology).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."