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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: DCP2

Summary for DCP2

Gene information	Gene symbol	DCP2
	Ensembl ID	ENSG00000172795
	Entrez ID	167227
	Gene name	decapping mRNA 2
	Synonyms	NUDT20
	Gene type	protein_coding
	UniProtAcc	Q8IU60

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Dataset with differentially expressed gene: DCP2

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE199333	patients	Bone marrow aspirate	Acute myeloid leukemia	Primary FLT3-ITD-mutated acute myeloid leukemia (AML)	Targeted therapy	gilteritinib	post	Malignant cells	-0.357549	0.00e+00

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Expression of DCP2 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to DCP2

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

Gene symbol	Mechanism
DCP2	Unusual Activation of Pro-survival Pathway

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MicroRNAs (miRNA) regulating DCP2

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
DCP2	hsa-miR-200a-3p	97.7159	NM_001242377
DCP2	hsa-miR-141-3p	97.7159	NM_001242377
DCP2	hsa-miR-148b-3p	96.8831	NM_001242377
DCP2	hsa-miR-148a-3p	96.8831	NM_001242377
DCP2	hsa-miR-152-3p	96.8831	NM_001242377
DCP2	hsa-miR-548as-3p	96.7025	NM_001242377
DCP2	hsa-miR-5696	96.528	NM_001242377
DCP2	hsa-miR-12136	94.4345	NM_001242377
DCP2	hsa-miR-548m	94.3041	NM_001242377
DCP2	hsa-miR-6778-3p	94.2803	NM_001242377
DCP2	hsa-miR-4251	94.264	NM_001242377
DCP2	hsa-miR-373-5p	93.7498	NM_001242377
DCP2	hsa-miR-616-5p	93.7498	NM_001242377
DCP2	hsa-miR-371b-5p	93.7498	NM_001242377
DCP2	hsa-miR-576-5p	93.385	NM_001242377
DCP2	hsa-miR-4324	93.091	NM_001242377
DCP2	hsa-miR-3613-3p	93.041	NM_001242377
DCP2	hsa-miR-20a-3p	92.7185	NM_001242377
DCP2	hsa-miR-4422	92.2064	NM_001242377
DCP2	hsa-miR-499a-5p	91.7939	NM_001242377
DCP2	hsa-miR-5700	91.2425	NM_001242377
DCP2	hsa-miR-548ai	90.9138	NM_001242377
DCP2	hsa-miR-548ba	90.9138	NM_001242377
DCP2	hsa-miR-570-5p	90.9138	NM_001242377
DCP2	hsa-miR-548ag	90.9138	NM_001242377
DCP2	hsa-miR-3143	90.7854	NM_001242377
DCP2	hsa-miR-4729	89.2307	NM_001242377
DCP2	hsa-miR-302c-5p	88.982	NM_001242377
DCP2	hsa-miR-548at-5p	88.6906	NM_001242377
DCP2	hsa-miR-203a-3p	88.0963	NM_001242377
DCP2	hsa-let-7f-2-3p	86.4173	NM_001242377
DCP2	hsa-miR-1185-2-3p	86.4173	NM_001242377
DCP2	hsa-miR-1185-1-3p	86.4173	NM_001242377
DCP2	hsa-miR-579-3p	85.6361	NM_001242377
DCP2	hsa-miR-664b-3p	85.6361	NM_001242377
DCP2	hsa-miR-548e-5p	85.4381	NM_001242377
DCP2	hsa-miR-411-3p	85.1294	NM_001242377
DCP2	hsa-miR-379-3p	85.1294	NM_001242377
DCP2	hsa-miR-580-3p	84.9453	NM_001242377
DCP2	hsa-miR-3622b-3p	84.5064	NM_001242377
DCP2	hsa-miR-3622a-3p	84.5064	NM_001242377
DCP2	hsa-miR-6826-3p	84.0906	NM_001242377
DCP2	hsa-miR-4427	83.6015	NM_001242377
DCP2	hsa-miR-153-5p	83.585	NM_001242377
DCP2	hsa-miR-4724-5p	83.3769	NM_001242377
DCP2	hsa-miR-544a	83.2417	NM_001242377
DCP2	hsa-miR-10527-5p	83.0194	NM_001242377
DCP2	hsa-miR-2355-3p	81.796	NM_001242377
DCP2	hsa-miR-4645-3p	81.7248	NM_001242377
DCP2	hsa-miR-1-3p	81.6196	NM_001242377

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Motifs and transcription factors (TFs) regulating DCP2

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
DCP2	metacluster_135.8	ZNF516; ZNF536 (inferredBy_Orthology).
DCP2	taipale_tf_pairs__GCM1_SPDEF_RTGNKGGCGGAWG_CAP_repr	GCM1; SPDEF (directAnnotation).
DCP2	kznf__ZNF730_Imbeault2017_RP_RCADE	ZNF730 (directAnnotation).
DCP2	hocomoco__ZFP57_MOUSE.H11MO.0.B	ZFP57 (inferredBy_Orthology).
DCP2	taipale_tf_pairs__ETV5_TCF3_RNCGGAAGNNNNNCASSTGN_CAP_repr	ETV5; TCF3 (directAnnotation).
DCP2	kznf__ZNF213_Schmitges2016_RCADE	ZNF213 (directAnnotation).
DCP2	metacluster_126.4	ZNF12; ZNF12; ZNF44; ZNF563; ZNF93 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."