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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: ZBTB41

Summary for ZBTB41

Gene information	Gene symbol	ZBTB41
	Ensembl ID	ENSG00000177888
	Entrez ID	360023
	Gene name	zinc finger and BTB domain containing 41
	Synonyms	DKFZp686C06120\|FLJ36199\|FRBZ1\|ZNF924
	Gene type	protein_coding
	UniProtAcc	Q5SVQ8

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Dataset with differentially expressed gene: ZBTB41

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE175716	PDX	Tumor tissue	Liver cancer	Advanced hepatocellular carcinoma	Targeted therapy	sorafenib	NA	Malignant cells	-0.453548	0.00e+00

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Expression of ZBTB41 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to ZBTB41

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ZBTB41

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
ZBTB41	hsa-miR-802	87.41	NM_194314
ZBTB41	hsa-miR-190a-5p	87.1312	NM_194314
ZBTB41	hsa-miR-190b-5p	87.1312	NM_194314
ZBTB41	hsa-miR-568	87.1037	NM_194314
ZBTB41	hsa-miR-600	87.0671	NM_194314
ZBTB41	hsa-miR-4762-3p	86.8471	NM_194314
ZBTB41	hsa-miR-5692c	86.7552	NM_194314
ZBTB41	hsa-miR-5692b	86.7552	NM_194314
ZBTB41	hsa-miR-4758-3p	86.6606	NM_194314
ZBTB41	hsa-miR-3125	86.4971	NM_194314
ZBTB41	hsa-miR-494-3p	86.4062	NM_194314
ZBTB41	hsa-miR-9-3p	86.399	NM_194314
ZBTB41	hsa-miR-548aw	85.9472	NM_194314
ZBTB41	hsa-miR-548aj-3p	85.5989	NM_194314
ZBTB41	hsa-miR-548x-3p	85.5989	NM_194314
ZBTB41	hsa-miR-6868-3p	85.4853	NM_194314
ZBTB41	hsa-miR-135a-3p	85.4286	NM_194314
ZBTB41	hsa-miR-647	85.3662	NM_194314
ZBTB41	hsa-miR-340-5p	85.1214	NM_194314
ZBTB41	hsa-miR-3916	84.8469	NM_194314
ZBTB41	hsa-miR-12124	84.5677	NM_194314
ZBTB41	hsa-miR-7849-3p	84.4076	NM_194314
ZBTB41	hsa-miR-12119	84.3827	NM_194314
ZBTB41	hsa-miR-10522-5p	84.1257	NM_194314
ZBTB41	hsa-miR-605-3p	84.0963	NM_194314
ZBTB41	hsa-miR-6859-5p	84.0644	NM_194314
ZBTB41	hsa-miR-1248	83.8456	NM_194314
ZBTB41	hsa-miR-1250-3p	83.7846	NM_194314
ZBTB41	hsa-miR-143-3p	83.3597	NM_194314
ZBTB41	hsa-miR-4770	83.3597	NM_194314
ZBTB41	hsa-miR-578	83.1892	NM_194314
ZBTB41	hsa-miR-4495	83.058	NM_194314
ZBTB41	hsa-miR-3924	82.8876	NM_194314
ZBTB41	hsa-miR-651-3p	82.8668	NM_194314
ZBTB41	hsa-miR-539-5p	82.8275	NM_194314
ZBTB41	hsa-miR-548ae-3p	82.7827	NM_194314
ZBTB41	hsa-miR-548aq-3p	82.7827	NM_194314
ZBTB41	hsa-miR-6833-5p	82.7569	NM_194314
ZBTB41	hsa-miR-520f-5p	82.5284	NM_194314
ZBTB41	hsa-miR-877-3p	82.2548	NM_194314
ZBTB41	hsa-miR-4457	82.2221	NM_194314
ZBTB41	hsa-miR-153-5p	81.6676	NM_194314
ZBTB41	hsa-miR-4262	81.556	NM_194314
ZBTB41	hsa-miR-2054	81.5398	NM_194314
ZBTB41	hsa-miR-4255	81.3134	NM_194314
ZBTB41	hsa-miR-3975	81.0987	NM_194314
ZBTB41	hsa-miR-4717-5p	81.0764	NM_194314
ZBTB41	hsa-miR-562	81.0565	NM_194314
ZBTB41	hsa-miR-4672	80.9875	NM_194314
ZBTB41	hsa-miR-8083	80.8885	NM_194314

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Motifs and transcription factors (TFs) regulating ZBTB41

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."