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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: RSBN1

Summary for RSBN1

Gene information	Gene symbol	RSBN1
	Ensembl ID	ENSG00000081019
	Entrez ID	54665
	Gene name	round spermatid basic protein 1
	Synonyms	FLJ11220\|ROSBIN
	Gene type	protein_coding
	UniProtAcc	Q5VWQ0

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Dataset with differentially expressed gene: RSBN1

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE138267	CDX	Tumor tissue	Lung cancer	Small cell lung cancer (SCLC)	Chemotherapy	NA	NA	Malignant cells	0.250756	0.00e+00

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Expression of RSBN1 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to RSBN1

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating RSBN1

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
RSBN1	hsa-miR-542-3p	84.7714	NM_018364
RSBN1	hsa-miR-6833-3p	84.5332	NM_018364
RSBN1	hsa-miR-3145-3p	84.1795	NM_018364
RSBN1	hsa-miR-1250-3p	83.9652	NM_018364
RSBN1	hsa-miR-130b-5p	83.9471	NM_018364
RSBN1	hsa-miR-1253	83.3728	NM_018364
RSBN1	hsa-miR-664b-5p	83.266	NM_018364
RSBN1	hsa-miR-569	82.782	NM_018364
RSBN1	hsa-miR-1200	82.7756	NM_018364
RSBN1	hsa-miR-3132	82.6895	NM_018364
RSBN1	hsa-miR-197-5p	82.6895	NM_018364
RSBN1	hsa-miR-4768-5p	82.5114	NM_018364
RSBN1	hsa-miR-4324	82.422	NM_018364
RSBN1	hsa-miR-664a-3p	82.0608	NM_018364
RSBN1	hsa-miR-126-5p	82.0009	NM_018364
RSBN1	hsa-miR-8066	81.7819	NM_018364
RSBN1	hsa-miR-15b-5p	81.6029	NM_018364
RSBN1	hsa-miR-15a-5p	81.6029	NM_018364
RSBN1	hsa-miR-195-5p	81.6029	NM_018364
RSBN1	hsa-miR-16-5p	81.6029	NM_018364
RSBN1	hsa-miR-1301-3p	81.1721	NM_018364
RSBN1	hsa-miR-5047	81.1721	NM_018364
RSBN1	hsa-miR-8087	81.0194	NM_018364
RSBN1	hsa-miR-5011-5p	80.9776	NM_018364
RSBN1	hsa-miR-3663-5p	80.7117	NM_018364
RSBN1	hsa-miR-4633-5p	80.5749	NM_018364
RSBN1	hsa-miR-3919	80.4337	NM_018364
RSBN1	hsa-miR-3160-5p	80.09	NM_018364
RSBN1	hsa-miR-449b-3p	80.041	NM_018364

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Motifs and transcription factors (TFs) regulating RSBN1

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."