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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: CAMSAP2

Summary for CAMSAP2

Gene information	Gene symbol	CAMSAP2
	Ensembl ID	ENSG00000118200
	Entrez ID	23271
	Gene name	calmodulin regulated spectrin associated protein family member 2
	Synonyms	CAMSAP1L1\|KIAA1078
	Gene type	protein_coding
	UniProtAcc	Q08AD1

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Dataset with differentially expressed gene: CAMSAP2

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE186960	Panc1 cell line	Cell line	Pancreatic cancer	Pancreatic ductal adenocarcinoma (PDAC)	Chemotherapy	gemcitabine	NA	Malignant cells	-0.42412	3.36e-32

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Expression of CAMSAP2 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to CAMSAP2

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating CAMSAP2

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
CAMSAP2	hsa-miR-6504-3p	84.2203	NM_001297707
CAMSAP2	hsa-miR-10399-5p	84.2203	NM_001297707
CAMSAP2	hsa-miR-186-5p	84.1539	NM_001297707
CAMSAP2	hsa-miR-548o-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548w	83.7891	NM_001297707
CAMSAP2	hsa-miR-548ae-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548as-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548ad-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548ar-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548b-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548j-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548d-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548au-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548ay-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548c-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548a-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548ap-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548i	83.7891	NM_001297707
CAMSAP2	hsa-miR-548aq-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548bb-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548ak	83.7891	NM_001297707
CAMSAP2	hsa-miR-548ab	83.7891	NM_001297707
CAMSAP2	hsa-miR-548am-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-548y	83.7891	NM_001297707
CAMSAP2	hsa-miR-548h-5p	83.7891	NM_001297707
CAMSAP2	hsa-miR-23c	83.7187	NM_001297707
CAMSAP2	hsa-miR-23b-3p	83.7187	NM_001297707
CAMSAP2	hsa-miR-23a-3p	83.7187	NM_001297707
CAMSAP2	hsa-miR-4276	83.6025	NM_001297707
CAMSAP2	hsa-miR-519c-3p	83.5254	NM_001297707
CAMSAP2	hsa-miR-519b-3p	83.5254	NM_001297707
CAMSAP2	hsa-miR-519a-3p	83.5254	NM_001297707
CAMSAP2	hsa-miR-3148	82.2561	NM_001297708
CAMSAP2	hsa-miR-498-3p	82.0576	NM_001297707
CAMSAP2	hsa-miR-541-5p	81.8475	NM_001297708
CAMSAP2	hsa-miR-5003-5p	81.7343	NM_001297707
CAMSAP2	hsa-miR-5680	81.7231	NM_001297707
CAMSAP2	hsa-miR-26b-5p	81.4692	NM_001297707
CAMSAP2	hsa-miR-26a-5p	81.4692	NM_001297707
CAMSAP2	hsa-miR-12135	81.3632	NM_001297708
CAMSAP2	hsa-miR-205-5p	80.9179	NM_001297708
CAMSAP2	hsa-miR-646	80.8428	NM_001297707
CAMSAP2	hsa-miR-6768-3p	80.8241	NM_001297708
CAMSAP2	hsa-miR-29a-3p	80.4543	NM_001297707
CAMSAP2	hsa-miR-29c-3p	80.4543	NM_001297707
CAMSAP2	hsa-miR-29b-3p	80.4543	NM_001297707

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Motifs and transcription factors (TFs) regulating CAMSAP2

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
CAMSAP2	taipale_tf_pairs__ETV5_HOXA2_RSCGGWAATKR_CAP	ETV5; HOXA2 (directAnnotation).
CAMSAP2	metacluster_138.2	ELF1; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK3; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ERF; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS2; ETS2; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV5; ETV5; FEV; FLI1; FLI1; GABPA; GABPA; KMT2B; SPDEF; SPDEF; SPDEF; ZBTB11; ZNF518A; ZNF580 (directAnnotation). ELF1; ELF2; ELF4; ELK1; ELK1; ELK3; ELK4; ERG; ETS1; ETS2; ETV1; ETV2; ETV3; ETV4; ETV5; FEV; FLI1; FLI1; GABPA; SPDEF; SPDEF (inferredBy_Orthology).
CAMSAP2	metacluster_33.8	BRCA1; CHD2; CHD2; ETS1; NR3C1; ZBED1; ZBED1; ZBED1; ZBTB33; ZBTB33; ZBTB33; ZBTB33; ZBTB33; ZBTB33; ZBTB33 (directAnnotation). CHD2; ZBTB33 (inferredBy_Orthology).
CAMSAP2	metacluster_141.6	MZF1; TAF1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY2; YY2; ZFP42; ZFP42; ZFP42; ZFP42; ZFP42; ZFP42; ZNF597 (directAnnotation). TAF1; TAF1L (inferredBy_Orthology).
CAMSAP2	taipale_tf_pairs__ETV5_EVX1_RSCGGWAATKR_CAP	ETV5; EVX1 (directAnnotation).
CAMSAP2	taipale_tf_pairs__E2F1_ELK1_SGCGCNNNNNCGGAAGN_CAP_repr	E2F1; ELK1 (directAnnotation).
CAMSAP2	taipale_tf_pairs__FOXO1_ETV1_RCCGGAWGTKKN_CAP	ETV1; FOXO1 (directAnnotation).
CAMSAP2	jaspar__MA0748.2	YY2 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."