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Center for Computational Systems Medicine
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Gene summary

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Datasets with differential expression of this gene

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Expression of this gene in the resistant group across all datasets and cell types

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Significant ligand-receptor pairs related to this gene (This gene does not contain this module)

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Known drug resistance mechanisms of this gene (This gene does not contain this module)

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MicroRNAs (miRNAs) regulating this gene

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Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)

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Acts as a transcription factor (This gene does not contain this module)

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Acts as a drug target< (This gene does not contain this module)

Gene: ZNF37A

Summary for ZNF37A

Gene informationGene symbol

ZNF37A

Ensembl ID

ENSG00000075407

Entrez ID

7587

Gene namezinc finger protein 37A
SynonymsKOX21|ZNF37
Gene typeprotein_coding
UniProtAcc

NA


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Dataset with differentially expressed gene: ZNF37A

check buttonDifferentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.
DatasetSourceTissueCancer type level1Cancer type level2Drug typeRegimenTimepointCell typeavg_log2FCp_val_adj

GSE140440

DU145 and PC cell linesCell lineProstate cancerProstate cancerChemotherapydocetaxelNAMalignant cells-1.253924.59e-04

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Expression of ZNF37A in the resistant group across all datasets and cell types

check buttonRed dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)
boxplot

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Significant ligand-receptor pairs related to ZNF37A

check buttonThis table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

check buttonThis table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ZNF37A

check buttonThis table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)
Gene symbolmiRNAScoreGeneBank accession
ZNF37Ahsa-miR-6890-5p84.1039NM_001007094
ZNF37Ahsa-miR-4436b-5p83.4868NM_001007094
ZNF37Ahsa-miR-6801-3p83.2944NM_001324259
ZNF37Ahsa-miR-331-3p83.2944NM_001324259
ZNF37Ahsa-miR-642a-5p83.1112NM_001007094
ZNF37Ahsa-miR-29883.0785NM_001007094
ZNF37Ahsa-miR-479482.4312NM_001324252
ZNF37Ahsa-miR-6504-5p82.2563NM_001324260
ZNF37Ahsa-miR-3085-3p82.2563NM_001324260
ZNF37Ahsa-miR-3064-5p82.2563NM_001324260
ZNF37Ahsa-miR-6515-3p81.2839NM_001324260
ZNF37Ahsa-miR-211381.2695NM_001324258
ZNF37Ahsa-miR-4714-5p80.9347NM_001324258
ZNF37Ahsa-miR-590-3p80.8484NM_001324260
ZNF37Ahsa-miR-477580.6521NM_001324252
ZNF37Ahsa-miR-4768-3p80.5405NM_001324258
ZNF37Ahsa-miR-3679-3p80.1114NM_001324259
ZNF37Ahsa-miR-6833-3p80.0465NM_001324259
ZNF37Ahsa-miR-428280.0286NM_001324252
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Motifs and transcription factors (TFs) regulating ZNF37A

check buttonThis table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

check buttonThis table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

check buttonThis table shows that this differential gene acts as a drug target.



1"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."