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Center for Computational Systems Medicine
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Gene summary

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Datasets with differential expression of this gene

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Expression of this gene in the resistant group across all datasets and cell types

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Significant ligand-receptor pairs related to this gene (This gene does not contain this module)

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Known drug resistance mechanisms of this gene (This gene does not contain this module)

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MicroRNAs (miRNAs) regulating this gene

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Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)

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Acts as a transcription factor (This gene does not contain this module)

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Acts as a drug target< (This gene does not contain this module)

Gene: ZNF124

Summary for ZNF124

Gene informationGene symbol

ZNF124

Ensembl ID

ENSG00000196418

Entrez ID

7678

Gene namezinc finger protein 124
SynonymsHZF-16|HZF16
Gene typeprotein_coding
UniProtAcc

Q15973


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Dataset with differentially expressed gene: ZNF124

check buttonDifferentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.
DatasetSourceTissueCancer type level1Cancer type level2Drug typeRegimenTimepointCell typeavg_log2FCp_val_adj

GSE140440

DU145 and PC cell linesCell lineProstate cancerProstate cancerChemotherapydocetaxelNAMalignant cells-1.122183.47e-02

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Expression of ZNF124 in the resistant group across all datasets and cell types

check buttonRed dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)
boxplot

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Significant ligand-receptor pairs related to ZNF124

check buttonThis table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

check buttonThis table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ZNF124

check buttonThis table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)
Gene symbolmiRNAScoreGeneBank accession
ZNF124hsa-miR-7156-3p86.0313NM_001243740
ZNF124hsa-miR-568385.4321NM_003431
ZNF124hsa-miR-296-3p84.9039NM_001297569
ZNF124hsa-miR-314884.8735NM_003431
ZNF124hsa-miR-425-5p84.2297NM_001243740
ZNF124hsa-miR-365a-3p84.1357NM_001297567
ZNF124hsa-miR-365b-3p84.1357NM_001297567
ZNF124hsa-miR-368683.8637NM_001243740
ZNF124hsa-miR-4774-5p83.6619NM_001243740
ZNF124hsa-miR-6758-3p83.6174NM_003431
ZNF124hsa-miR-6809-3p83.1477NM_001297569
ZNF124hsa-miR-593-3p82.9659NM_001297569
ZNF124hsa-miR-129082.8674NM_001297569
ZNF124hsa-miR-4662a-5p82.8639NM_003431
ZNF124hsa-miR-371b-5p82.6848NM_003431
ZNF124hsa-miR-616-5p82.6848NM_003431
ZNF124hsa-miR-373-5p82.6848NM_003431
ZNF124hsa-miR-548g-3p82.6372NM_003431
ZNF124hsa-miR-4789-3p82.4431NM_001243740
ZNF124hsa-miR-3156-3p82.2381NM_001297569
ZNF124hsa-miR-1260a82.2381NM_001297569
ZNF124hsa-miR-1260b82.2381NM_001297569
ZNF124hsa-miR-4717-3p81.4575NM_001297567
ZNF124hsa-miR-4802-3p81.2932NM_001297569
ZNF124hsa-miR-1229-5p81.1235NM_003431
ZNF124hsa-miR-526b-5p80.882NM_003431
ZNF124hsa-miR-511-3p80.8058NM_001297567
ZNF124hsa-miR-4724-3p80.6385NM_001297569
ZNF124hsa-miR-4668-5p80.1749NM_003431
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Motifs and transcription factors (TFs) regulating ZNF124

check buttonThis table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

check buttonThis table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

check buttonThis table shows that this differential gene acts as a drug target.



1"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."