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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: ZCCHC14

Summary for ZCCHC14

Gene information	Gene symbol	ZCCHC14
	Ensembl ID	ENSG00000140948
	Entrez ID	23174
	Gene name	zinc finger CCHC-type containing 14
	Synonyms	BDG29\|MGC14139
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: ZCCHC14

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	0.990507	1.53e-02

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Expression of ZCCHC14 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to ZCCHC14

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ZCCHC14

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
ZCCHC14	hsa-miR-4666a-5p	84.2662	NM_015144
ZCCHC14	hsa-miR-6878-5p	84.2197	NM_015144
ZCCHC14	hsa-miR-96-5p	84.1103	NM_015144
ZCCHC14	hsa-miR-7856-5p	83.8908	NM_015144
ZCCHC14	hsa-let-7c-3p	83.7104	NM_015144
ZCCHC14	hsa-miR-548at-5p	83.5744	NM_015144
ZCCHC14	hsa-miR-6501-5p	83.0125	NM_015144
ZCCHC14	hsa-miR-548aa	82.8157	NM_015144
ZCCHC14	hsa-miR-548ap-3p	82.8157	NM_015144
ZCCHC14	hsa-miR-548t-3p	82.8157	NM_015144
ZCCHC14	hsa-miR-4535	82.4803	NM_015144
ZCCHC14	hsa-miR-4482-3p	82.4382	NM_015144
ZCCHC14	hsa-miR-4721	82.4228	NM_015144
ZCCHC14	hsa-miR-454-3p	81.8942	NM_015144
ZCCHC14	hsa-miR-6788-5p	81.5889	NM_015144
ZCCHC14	hsa-miR-30c-2-3p	81.5889	NM_015144
ZCCHC14	hsa-miR-30c-1-3p	81.5889	NM_015144
ZCCHC14	hsa-miR-548aj-3p	81.2635	NM_015144
ZCCHC14	hsa-miR-548x-3p	81.2635	NM_015144
ZCCHC14	hsa-miR-3659	81.1772	NM_015144
ZCCHC14	hsa-miR-4433b-5p	81.081	NM_015144
ZCCHC14	hsa-miR-4779	80.9308	NM_015144
ZCCHC14	hsa-miR-1270	80.7401	NM_015144
ZCCHC14	hsa-miR-605-5p	80.6814	NM_015144
ZCCHC14	hsa-miR-130a-3p	80.5581	NM_015144
ZCCHC14	hsa-miR-1246	80.4777	NM_015144
ZCCHC14	hsa-miR-620	80.4128	NM_015144
ZCCHC14	hsa-miR-5590-3p	80.2569	NM_015144
ZCCHC14	hsa-miR-142-5p	80.2569	NM_015144
ZCCHC14	hsa-miR-1271-5p	80.2365	NM_015144
ZCCHC14	hsa-miR-12133	80.2365	NM_015144
ZCCHC14	hsa-miR-4756-3p	80.1664	NM_015144
ZCCHC14	hsa-miR-7159-3p	80.0243	NM_015144

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Motifs and transcription factors (TFs) regulating ZCCHC14

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
ZCCHC14	metacluster_3.5	KLF14; KLF15; KLF15; KLF16 (directAnnotation).
ZCCHC14	swissregulon__hs__CHD1	CHD1 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."