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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene (This gene does not contain this module)
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: RAB3C

Summary for RAB3C

Gene information	Gene symbol	RAB3C
	Ensembl ID	ENSG00000152932
	Entrez ID	115827
	Gene name	RAB3C, member RAS oncogene family
	Synonyms	NA
	Gene type	protein_coding
	UniProtAcc	Q96E17

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Dataset with differentially expressed gene: RAB3C

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE115251	Kelly cell line	Cell line	Neuroblastoma	Neuroblastoma	Targeted therapy	TAE684	NA	Malignant cells	-0.306924	0.00e+00

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Expression of RAB3C in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to RAB3C

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating RAB3C

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
RAB3C	hsa-miR-1910-3p	88.4123	NM_001317915
RAB3C	hsa-miR-7-1-3p	88.1785	NM_001317915
RAB3C	hsa-miR-4303	88.1376	NM_001317915
RAB3C	hsa-miR-4264	88.1017	NM_001317915
RAB3C	hsa-miR-548n	87.306	NM_001317915
RAB3C	hsa-miR-340-5p	87.3006	NM_001317915
RAB3C	hsa-miR-5582-3p	87.1741	NM_001317915
RAB3C	hsa-miR-3662	87.1072	NM_001317915
RAB3C	hsa-miR-6808-5p	86.9218	NM_001317915
RAB3C	hsa-miR-940	86.9218	NM_001317915
RAB3C	hsa-miR-6893-5p	86.9218	NM_001317915
RAB3C	hsa-miR-4762-3p	86.7417	NM_001317915
RAB3C	hsa-miR-5701	86.568	NM_001317915
RAB3C	hsa-miR-7-2-3p	86.3847	NM_001317915
RAB3C	hsa-miR-5692a	86.3576	NM_001317915
RAB3C	hsa-miR-877-3p	85.6342	NM_001317915
RAB3C	hsa-miR-4797-3p	85.5719	NM_001317915
RAB3C	hsa-miR-4262	85.4368	NM_001317915
RAB3C	hsa-miR-766-5p	84.7946	NM_001317915
RAB3C	hsa-miR-381-3p	84.7839	NM_001317915
RAB3C	hsa-miR-300	84.7839	NM_001317915
RAB3C	hsa-miR-511-3p	84.2223	NM_001317915
RAB3C	hsa-miR-155-3p	84.1905	NM_001317915
RAB3C	hsa-miR-4799-3p	83.8783	NM_001317915
RAB3C	hsa-miR-5588-5p	83.8783	NM_001317915
RAB3C	hsa-miR-4720-5p	83.8783	NM_001317915
RAB3C	hsa-miR-584-3p	83.7386	NM_001317915
RAB3C	hsa-miR-181c-5p	83.1828	NM_001317915
RAB3C	hsa-miR-181b-5p	83.1828	NM_001317915
RAB3C	hsa-miR-181a-5p	83.1828	NM_001317915
RAB3C	hsa-miR-181d-5p	83.1828	NM_001317915
RAB3C	hsa-miR-3606-5p	82.9495	NM_001317915
RAB3C	hsa-miR-3913-3p	82.708	NM_001317915
RAB3C	hsa-miR-4760-5p	82.6516	NM_001317915
RAB3C	hsa-miR-7162-3p	82.3524	NM_001317915
RAB3C	hsa-miR-425-5p	81.8152	NM_001317915
RAB3C	hsa-miR-218-1-3p	81.7763	NM_001317915
RAB3C	hsa-miR-548x-3p	81.6453	NM_001317915
RAB3C	hsa-miR-548aj-3p	81.6453	NM_001317915
RAB3C	hsa-miR-190b-3p	81.0336	NM_001317915
RAB3C	hsa-miR-3613-5p	80.8481	NM_001317915
RAB3C	hsa-miR-1252-5p	80.7677	NM_001317915
RAB3C	hsa-miR-548ah-3p	80.6838	NM_001317915
RAB3C	hsa-miR-548aq-3p	80.6838	NM_001317915
RAB3C	hsa-miR-548am-3p	80.6838	NM_001317915
RAB3C	hsa-miR-548j-3p	80.6838	NM_001317915
RAB3C	hsa-miR-548ae-3p	80.6838	NM_001317915
RAB3C	hsa-miR-3166	80.1905	NM_001317915
RAB3C	hsa-miR-205-5p	80.1564	NM_001317915

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Motifs and transcription factors (TFs) regulating RAB3C

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."