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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: NAA25

Summary for NAA25

Gene information	Gene symbol	NAA25
	Ensembl ID	ENSG00000111300
	Entrez ID	80018
	Gene name	N-alpha-acetyltransferase 25, NatB auxiliary subunit
	Synonyms	C12orf30\|FLJ13089
	Gene type	protein_coding
	UniProtAcc	Q14CX7

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Dataset with differentially expressed gene: NAA25

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE186960	Panc1 cell line	Cell line	Pancreatic cancer	Pancreatic ductal adenocarcinoma (PDAC)	Chemotherapy	gemcitabine	NA	Malignant cells	-0.390856	3.02e-23

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Expression of NAA25 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to NAA25

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating NAA25

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
NAA25	hsa-miR-7159-5p	83.6134	NM_024953
NAA25	hsa-miR-548aw	83.4324	NM_024953
NAA25	hsa-miR-205-5p	83.3861	NM_024953
NAA25	hsa-miR-6514-3p	82.5212	NM_024953
NAA25	hsa-miR-31-3p	82.299	NM_024953
NAA25	hsa-miR-1277-5p	82.27	NM_024953
NAA25	hsa-miR-4775	82.2278	NM_024953
NAA25	hsa-miR-516b-5p	82.0535	NM_024953
NAA25	hsa-miR-3143	81.8326	NM_024953
NAA25	hsa-miR-3915	81.8202	NM_024953
NAA25	hsa-miR-3194-5p	81.3047	NM_024953
NAA25	hsa-miR-622	80.4261	NM_024953
NAA25	hsa-miR-30d-3p	80.1686	NM_024953
NAA25	hsa-miR-30a-3p	80.1686	NM_024953
NAA25	hsa-miR-30e-3p	80.1686	NM_024953

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Motifs and transcription factors (TFs) regulating NAA25

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
NAA25	taipale_cyt_meth__ZNF385D_NCGTCGCGACGN_eDBD_meth	ZNF385D (directAnnotation).
NAA25	taipale_tf_pairs__E2F1_ELK1_SGCGCNNNNNCGGAAGN_CAP_repr	E2F1; ELK1 (directAnnotation).
NAA25	metacluster_182.10	ZFX (directAnnotation).
NAA25	transfac_pro__M06173	ZNF85 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."