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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: NAA15

Summary for NAA15

Gene information	Gene symbol	NAA15
	Ensembl ID	ENSG00000164134
	Entrez ID	80155
	Gene name	N-alpha-acetyltransferase 15, NatA auxiliary subunit
	Synonyms	FLJ13340\|NARG1\|NATH\|TBDN100
	Gene type	protein_coding
	UniProtAcc	NA

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Dataset with differentially expressed gene: NAA15

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE140440	DU145 and PC cell lines	Cell line	Prostate cancer	Prostate cancer	Chemotherapy	docetaxel	NA	Malignant cells	-0.817353	1.23e-03
GSE186960	Panc1 cell line	Cell line	Pancreatic cancer	Pancreatic ductal adenocarcinoma (PDAC)	Chemotherapy	gemcitabine	NA	Malignant cells	-0.489513	8.36e-36

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Expression of NAA15 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to NAA15

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating NAA15

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
NAA15	hsa-miR-506-3p	89.7601	NM_057175
NAA15	hsa-miR-145-5p	89.5932	NM_057175
NAA15	hsa-miR-5195-3p	89.5932	NM_057175
NAA15	hsa-miR-211-5p	89.5738	NM_057175
NAA15	hsa-miR-204-5p	89.5738	NM_057175
NAA15	hsa-miR-374b-3p	89.568	NM_057175
NAA15	hsa-miR-3120-5p	89.3106	NM_057175
NAA15	hsa-miR-6501-3p	89.0998	NM_057175
NAA15	hsa-miR-4261	89.0981	NM_057175
NAA15	hsa-miR-548s	88.9407	NM_057175
NAA15	hsa-miR-218-5p	88.8709	NM_057175
NAA15	hsa-miR-6774-5p	88.6754	NM_057175
NAA15	hsa-miR-548x-3p	88.3576	NM_057175
NAA15	hsa-miR-548aj-3p	88.3576	NM_057175
NAA15	hsa-miR-4666a-3p	88.2573	NM_057175
NAA15	hsa-miR-22-5p	88.1852	NM_057175
NAA15	hsa-miR-7111-3p	87.388	NM_057175
NAA15	hsa-miR-4638-3p	87.3042	NM_057175
NAA15	hsa-miR-147b-5p	87.1068	NM_057175
NAA15	hsa-miR-3938	87.0797	NM_057175
NAA15	hsa-miR-9-3p	87.004	NM_057175
NAA15	hsa-miR-1263	86.671	NM_057175
NAA15	hsa-miR-5688	86.5458	NM_057175
NAA15	hsa-miR-1285-5p	86.2699	NM_057175
NAA15	hsa-miR-151a-3p	86.2569	NM_057175
NAA15	hsa-miR-6074	85.6523	NM_057175
NAA15	hsa-miR-626	85.5575	NM_057175
NAA15	hsa-miR-6876-3p	85.5575	NM_057175
NAA15	hsa-miR-4251	85.5436	NM_057175
NAA15	hsa-miR-3064-3p	85.2775	NM_057175
NAA15	hsa-miR-4318	85.2741	NM_057175
NAA15	hsa-miR-3679-3p	85.1934	NM_057175
NAA15	hsa-miR-1200	84.9815	NM_057175
NAA15	hsa-miR-548aq-3p	84.3846	NM_057175
NAA15	hsa-miR-548ae-3p	84.3846	NM_057175
NAA15	hsa-miR-548am-3p	84.3846	NM_057175
NAA15	hsa-miR-548j-3p	84.3846	NM_057175
NAA15	hsa-miR-548ah-3p	84.3846	NM_057175
NAA15	hsa-miR-6828-3p	84.1562	NM_057175
NAA15	hsa-miR-6126	83.9244	NM_057175
NAA15	hsa-miR-4324	83.6025	NM_057175
NAA15	hsa-miR-338-5p	83.5178	NM_057175
NAA15	hsa-miR-4291	83.3532	NM_057175
NAA15	hsa-miR-4703-5p	83.2095	NM_057175
NAA15	hsa-miR-495-3p	82.9827	NM_057175
NAA15	hsa-miR-6834-3p	82.8919	NM_057175
NAA15	hsa-miR-6761-5p	82.4202	NM_057175
NAA15	hsa-miR-1231	82.3369	NM_057175
NAA15	hsa-miR-28-3p	82.3096	NM_057175
NAA15	hsa-miR-6851-3p	82.1026	NM_057175

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Motifs and transcription factors (TFs) regulating NAA15

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
NAA15	metacluster_191.3	EHF; ELF1; ELF1; ELF1; ELF4; ELK1; ELK3; ELK3; ELK4; ELK4; ERF; ETS1; ETS2; ETV3; ETV4; ETV5; FEV; FEV; FLI1; FLI1; GABPA; GABPA; GABPA; GABPA; GABPA; GABPA; SPDEF; ZNF200 (directAnnotation). ELK1; ELK1; ELK3; ELK3; ELK4; ELK4; ETV1; ETV1; ETV4; ETV4; ETV4; ETV5; GABPA; GABPA (inferredBy_Orthology).
NAA15	metacluster_166.4	BCLAF1; EHF; ELF1; ELF1; ELF1; ELF1; ELF1; ELF1; ELF2; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK3; ELK3; ELK3; ELK3; ELK4; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS1; ETS1; ETS1; ETV1; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV4; ETV4; ETV4; ETV4; ETV5; ETV7; FEV; FEV; FLI1; FLI1; FLI1; FLI1; GABPA; GABPA; GABPA; GABPA; GABPA; GABPA; GABPB1; GATAD1; PHF20; ZBTB25; ZBTB40 (directAnnotation). EHF; ELF1; ELF1; ELF3; ELF5; ELK3; ELK4; ERG; ETS1; ETV1; ETV2; ETV4; FLI1; GABPA; GABPA (inferredBy_Orthology).
NAA15	taipale_tf_pairs__FOXO1_ELK3_RCCGGAWGTKKW_CAP	ELK3; FOXO1 (directAnnotation).
NAA15	hocomoco__TYY2_HUMAN.H11MO.0.D	YY2 (directAnnotation).
NAA15	metacluster_138.2	ELF1; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK3; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ERF; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS2; ETS2; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV5; ETV5; FEV; FLI1; FLI1; GABPA; GABPA; KMT2B; SPDEF; SPDEF; SPDEF; ZBTB11; ZNF518A; ZNF580 (directAnnotation). ELF1; ELF2; ELF4; ELK1; ELK1; ELK3; ELK4; ERG; ETS1; ETS2; ETV1; ETV2; ETV3; ETV4; ETV5; FEV; FLI1; FLI1; GABPA; SPDEF; SPDEF (inferredBy_Orthology).
NAA15	cisbp__M02645	ETS1 (directAnnotation).
NAA15	hdpi__ETV4	ETV4 (directAnnotation).
NAA15	metacluster_33.8	BRCA1; CHD2; CHD2; ETS1; NR3C1; ZBED1; ZBED1; ZBED1; ZBTB33; ZBTB33; ZBTB33; ZBTB33; ZBTB33; ZBTB33; ZBTB33 (directAnnotation). CHD2; ZBTB33 (inferredBy_Orthology).
NAA15	metacluster_141.2	E2F2; E2F3 (directAnnotation).
NAA15	metacluster_141.6	MZF1; TAF1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY2; YY2; ZFP42; ZFP42; ZFP42; ZFP42; ZFP42; ZFP42; ZNF597 (directAnnotation). TAF1; TAF1L (inferredBy_Orthology).
NAA15	transfac_pro__M04794	TAF1 (directAnnotation).
NAA15	taipale_tf_pairs__FOXO1_ETV1_RCCGGAWGTKKN_CAP	ETV1; FOXO1 (directAnnotation).
NAA15	jaspar__MA0748.2	YY2 (directAnnotation).
NAA15	transfac_pro__M01298	MECP2 (directAnnotation).
NAA15	metacluster_7.5	PLAGL1; PLAGL1 (directAnnotation).
NAA15	metacluster_182.10	ZFX (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."