Gene symbol | motif | TF_highConf |
MET | metacluster_135.11 | NR2C2 (directAnnotation). |
MET | metacluster_135.10 | MBD2; MBD2; MECP2; MECP2 (directAnnotation). |
MET | tfdimers__MD00038 | TFAP2C (directAnnotation). |
MET | metacluster_144.3 | ZNF704; ZNF704 (directAnnotation). |
MET | metacluster_7.13 | ZFX (directAnnotation). |
MET | kznf__ZNF730_Imbeault2017_RP_RCADE | ZNF730 (directAnnotation). |
MET | cisbp__M00968 | MTF2 (directAnnotation). |
MET | metacluster_155.23 | BCL11B; ZNF711; ZNF711 (directAnnotation). ZFY (inferredBy_Orthology). |
MET | metacluster_160.20 | JUND; PRDM15 (directAnnotation). |
MET | cisbp__M00341 | PAX6 (directAnnotation). |
MET | metacluster_198.3 | ZFP64 (directAnnotation). |
MET | metacluster_141.5 | NR3C1; THAP1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY1; YY2; YY2; ZNF597 (directAnnotation). YY1; YY1; YY1; YY2; ZFP42 (inferredBy_Orthology). |
MET | metacluster_151.1 | KAT7; PML; SMAD5; TAF1; ZFP37; ZGPAT; ZNF519; ZNF519; ZNF571; ZNF770; ZNF770; ZNF770; ZSCAN22; ZSCAN22 (directAnnotation). |
MET | jaspar__MA0185.1 | DEAF1 (inferredBy_Orthology). |
MET | metacluster_61.1 | DEAF1; DEAF1 (directAnnotation). |
MET | cisbp__M00788 | ZFY (inferredBy_Orthology). |
MET | kznf__ZNF213_Schmitges2016_RCADE | ZNF213 (directAnnotation). |
MET | metacluster_175.1 | ZNF283 (directAnnotation). |
MET | hdpi__ZNF304 | ZNF304 (directAnnotation). |
MET | transfac_pro__M02844 | BCL6B (inferredBy_Orthology). |
MET | metacluster_125.2 | TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2D; TFAP2D; TFAP2D; TFAP2E; TFAP2E; TFAP2E; TFAP2E; TFAP2E; TFAP2E; ZNF611; ZNF611 (directAnnotation). TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2A; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2B; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2C; TFAP2D; TFAP2D; TFAP2D; TFAP2D; TFAP2D; TFAP2D; TFAP2E; TFAP2E; TFAP2E; TFAP2E; TFAP2E; TFAP2E; TFAP2E (inferredBy_Orthology). |
MET | metacluster_133.1 | ZNF304; ZNF304; ZSCAN22 (directAnnotation). |
MET | transfac_pro__M01199 | TRIM28 (directAnnotation). |
MET | kznf__ZNF682_Isakova2017_SMiLE-seq | ZNF682 (directAnnotation). |
MET | metacluster_151.2 | ZNF23 (directAnnotation). |
MET | transfac_public__M00189 | TFAP2A; TFAP2B; TFAP2C (directAnnotation). |
MET | transfac_pro__M01219 | SP1 (directAnnotation). SP3 (inferredBy_Orthology). |
MET | transfac_pro__M03806 | ZBTB7C (directAnnotation). |
MET | transfac_pro__M00915 | TFAP2A; TFAP2B; TFAP2C (directAnnotation). |
MET | jaspar__MA0079.5 | SP1 (directAnnotation). |
MET | kznf__KLF1_Barrera2016.2_PBM | KLF1 (directAnnotation). |
MET | transfac_pro__M01253 | CNOT3 (directAnnotation). |
MET | transfac_pro__M04817 | ZBTB33 (directAnnotation). |
MET | taipale_cyt_meth__E2F2_GCGCGCGCGYW_eDBD_repr | E2F2 (directAnnotation). |
MET | cisbp__M07938 | E2F1 (directAnnotation). |
Target name | Drug name | Drug ID | Drug type |
MET | "1-(4-fluorophenyl)-N-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-2-oxo-1,2-dihydropyridin | DB06896 | small molecule |
MET | "1-[(2-NITROPHENYL)SULFONYL]-1H-PYRROLO[3,2-B]PYRIDINE-6-CARBOXAMIDE" | DB08791 | small molecule |
MET | "2-(4-fluorophenyl)-N-{[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]carbamoyl}acetamide" | DB06997 | small molecule |
MET | "3-[3-(4-methylpiperazin-1-yl)-7-(trifluoromethyl)quinoxalin-5-yl]phenol" | DB07969 | small molecule |
MET | "AMG-208" | DB08079 | small molecule |
MET | "Amivantamab" | DB16695 | biotech |
MET | "Amuvatinib" | DB12742 | small molecule |
MET | "Brigatinib" | DB12267 | small molecule |
MET | "Cabozantinib" | DB08875 | small molecule |
MET | "Capmatinib" | DB11791 | small molecule |
MET | "Crizotinib" | DB08865 | small molecule |
MET | "Fostamatinib" | DB12010 | small molecule |
MET | "K-252a" | DB02152 | small molecule |
MET | "N-(3-chlorophenyl)-N-methyl-2-oxo-3-[(3,4,5-trimethyl-1H-pyrrol-2-yl)methyl]-2H-indole-5-sulfonamid | DB07369 | small molecule |
MET | "N-({4-[(2-aminopyridin-4-yl)oxy]-3-fluorophenyl}carbamoyl)-2-(4-fluorophenyl)acetamide" | DB06995 | small molecule |
MET | "SGX-523" | DB06314 | small molecule |
MET | "Sunitinib" | DB01268 | small molecule |
MET | "Tepotinib" | DB15133 | small molecule |
MET | "Tivantinib" | DB12200 | small molecule |
MET | "Tivozanib" | DB11800 | small molecule |
1 | "Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618." |
2 | "Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335." |