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	Gene summary
	Datasets with differential expression of this gene
	Expression of this gene in the resistant group across all datasets and cell types
	Significant ligand-receptor pairs related to this gene (This gene does not contain this module)
	Known drug resistance mechanisms of this gene (This gene does not contain this module)
	MicroRNAs (miRNAs) regulating this gene
	Motifs and transcription factors (TFs) regulating this gene
	Acts as a transcription factor (This gene does not contain this module)
	Acts as a drug target< (This gene does not contain this module)

Gene: ABHD13

Summary for ABHD13

Gene information	Gene symbol	ABHD13
	Ensembl ID	ENSG00000139826
	Entrez ID	84945
	Gene name	abhydrolase domain containing 13
	Synonyms	bA153I24.2\|BEM46L1\|C13orf6\|FLJ14906
	Gene type	protein_coding
	UniProtAcc	Q7L211

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Dataset with differentially expressed gene: ABHD13

Differentially expression genes between the resistant and sensitive groups. A positive avg_log2FC represents significantly high expression in the resistant group, while a negative avg_log2FC represents significantly low expression in the resistant group.

Dataset	Source	Tissue	Cancer type level1	Cancer type level2	Drug type	Regimen	Timepoint	Cell type	avg_log2FC	p_val_adj
GSE108397	451Lu cell line	Cell line	Melanoma	Melanoma	Targeted therapy	PLX-4720	NA	Malignant cells	0.340318	0.00e+00

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Expression of ABHD13 in the resistant group across all datasets and cell types

Red dots represent significantly high expression in the resistant group, while blue dots represent significantly low expression in the resistant group. White dots represent that there is no significant difference in the expression of this gene between the resistant and sensitive groups. Blank represents that this cell type is not present in this dataset. (If the image exists, the user can click on it to enlarge it in a new window.)

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Significant ligand-receptor pairs related to ABHD13

This table shows the significant ligand-receptor pairs related to this gene across all datasets, timepoints and conditions. (Complete files can be downloaded from the download section.)

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Known drug resistance mechanisms of this gene

This table shows the known drug resistance mechanisms of this gene. Clicking on this gene will link to another database that displays more drug resistance-related information.

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MicroRNAs (miRNA) regulating ABHD13

This table shows the miRNAs with a score of more than 80 regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	miRNA	Score	GeneBank accession
ABHD13	hsa-miR-513a-3p	87.5287	NM_032859
ABHD13	hsa-miR-4699-3p	87.2187	NM_032859
ABHD13	hsa-miR-4801	87.0159	NM_032859
ABHD13	hsa-miR-448	86.5757	NM_032859
ABHD13	hsa-miR-5696	85.9088	NM_032859
ABHD13	hsa-miR-4327	85.5869	NM_032859
ABHD13	hsa-miR-96-5p	85.5554	NM_032859
ABHD13	hsa-miR-3153	85.5198	NM_032859
ABHD13	hsa-miR-568	85.1398	NM_032859
ABHD13	hsa-miR-92b-3p	84.9282	NM_032859
ABHD13	hsa-miR-92a-3p	84.9282	NM_032859
ABHD13	hsa-miR-32-5p	84.9282	NM_032859
ABHD13	hsa-miR-561-3p	84.7099	NM_032859
ABHD13	hsa-miR-3660	84.6965	NM_032859
ABHD13	hsa-miR-4526	84.6965	NM_032859
ABHD13	hsa-miR-548bb-3p	84.5282	NM_032859
ABHD13	hsa-miR-548ac	84.5282	NM_032859
ABHD13	hsa-miR-548h-3p	84.5282	NM_032859
ABHD13	hsa-miR-548z	84.5282	NM_032859
ABHD13	hsa-miR-548d-3p	84.5282	NM_032859
ABHD13	hsa-miR-3646	84.0225	NM_032859
ABHD13	hsa-miR-4802-5p	83.946	NM_032859
ABHD13	hsa-miR-1843	83.946	NM_032859
ABHD13	hsa-miR-5580-3p	83.8226	NM_032859
ABHD13	hsa-miR-4799-5p	83.4178	NM_032859
ABHD13	hsa-miR-3606-3p	83.2079	NM_032859
ABHD13	hsa-miR-6851-5p	83.0776	NM_032859
ABHD13	hsa-miR-3689d	83.0776	NM_032859
ABHD13	hsa-miR-8087	82.75	NM_032859
ABHD13	hsa-miR-590-3p	82.6267	NM_032859
ABHD13	hsa-miR-495-3p	82.5004	NM_032859
ABHD13	hsa-miR-25-3p	82.2323	NM_032859
ABHD13	hsa-miR-363-3p	82.2323	NM_032859
ABHD13	hsa-miR-367-3p	82.2323	NM_032859
ABHD13	hsa-miR-7844-5p	82.1786	NM_032859
ABHD13	hsa-miR-4731-3p	82.1462	NM_032859
ABHD13	hsa-miR-4297	82.0819	NM_032859
ABHD13	hsa-miR-153-3p	82.0581	NM_032859
ABHD13	hsa-miR-12133	81.8344	NM_032859
ABHD13	hsa-miR-1271-5p	81.8344	NM_032859
ABHD13	hsa-miR-5590-3p	81.651	NM_032859
ABHD13	hsa-miR-5688	81.0938	NM_032859
ABHD13	hsa-miR-578	81.0546	NM_032859
ABHD13	hsa-miR-5590-5p	80.8287	NM_032859
ABHD13	hsa-miR-4764-5p	80.7766	NM_032859
ABHD13	hsa-miR-548e-5p	80.4012	NM_032859
ABHD13	hsa-miR-32-3p	80.3973	NM_032859
ABHD13	hsa-miR-202-3p	80.2766	NM_032859
ABHD13	hsa-miR-216b-3p	80.1644	NM_032859

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Motifs and transcription factors (TFs) regulating ABHD13

This table shows the Motifs and transcription factors (TFs) regulating this gene. (Complete files can be downloaded from the download section.)

Gene symbol	motif	TF_highConf
ABHD13	jaspar__MA1933.1	SREBF2 (directAnnotation).
ABHD13	metacluster_191.2	ELK4; NR2C2; NR2C2; NR2C2; NR2C2 (directAnnotation). GABPA (inferredBy_Orthology).
ABHD13	taipale_tf_pairs__ETS2_RCCGGAAGTG_HT	ETS2 (directAnnotation).
ABHD13	metacluster_166.4	BCLAF1; EHF; ELF1; ELF1; ELF1; ELF1; ELF1; ELF1; ELF2; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK1; ELK3; ELK3; ELK3; ELK3; ELK4; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS1; ETS1; ETS1; ETV1; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV4; ETV4; ETV4; ETV4; ETV5; ETV7; FEV; FEV; FLI1; FLI1; FLI1; FLI1; GABPA; GABPA; GABPA; GABPA; GABPA; GABPA; GABPB1; GATAD1; PHF20; ZBTB25; ZBTB40 (directAnnotation). EHF; ELF1; ELF1; ELF3; ELF5; ELK3; ELK4; ERG; ETS1; ETV1; ETV2; ETV4; FLI1; GABPA; GABPA (inferredBy_Orthology).
ABHD13	taipale_tf_pairs__MEIS1_ELF1_NTGCCGGAAGTN_CAP_repr	ELF1; MEIS1 (directAnnotation).
ABHD13	metacluster_191.3	EHF; ELF1; ELF1; ELF1; ELF4; ELK1; ELK3; ELK3; ELK4; ELK4; ERF; ETS1; ETS2; ETV3; ETV4; ETV5; FEV; FEV; FLI1; FLI1; GABPA; GABPA; GABPA; GABPA; GABPA; GABPA; SPDEF; ZNF200 (directAnnotation). ELK1; ELK1; ELK3; ELK3; ELK4; ELK4; ETV1; ETV1; ETV4; ETV4; ETV4; ETV5; GABPA; GABPA (inferredBy_Orthology).
ABHD13	taipale_tf_pairs__ELK1_TBX21_TNRCACCGGAAGNN_CAP_repr	ELK1; TBX21 (directAnnotation).
ABHD13	taipale_tf_pairs__ETV5_HOXA2_RSCGGWAATKR_CAP	ETV5; HOXA2 (directAnnotation).
ABHD13	hdpi__ETV4	ETV4 (directAnnotation).
ABHD13	taipale_tf_pairs__ETV5_FOXI1_RSCGGATGTTGN_CAP	ETV5; FOXI1 (directAnnotation).
ABHD13	taipale_tf_pairs__ELK1_TEF_NSCGGAWNTTACGTAAN_CAP	ELK1; TEF (directAnnotation).
ABHD13	cisbp__M02645	ETS1 (directAnnotation).
ABHD13	taipale_tf_pairs__ETV2_HOXA2_NCCGGAAGTMATTA_CAP_repr	ETV2; HOXA2 (directAnnotation).
ABHD13	taipale_tf_pairs__FOXO1_ELK3_RCCGGAWGTKKW_CAP	ELK3; FOXO1 (directAnnotation).
ABHD13	taipale_tf_pairs__ETV5_EOMES_TNRCACCGGAWN_CAP	EOMES; ETV5 (directAnnotation).
ABHD13	metacluster_166.2	ELK4; ETS1; ETS1; ETV1; ETV3; ETV4; ETV5; ETV7 (directAnnotation). GABPA (inferredBy_Orthology).
ABHD13	taipale_tf_pairs__FOXO1_ELK1_TGTTGCCGGANNN_CAP	ELK1; FOXO1 (directAnnotation).
ABHD13	taipale_tf_pairs__ETV2_TCF3_CASSTGNNCCGGAWRYN_CAP_repr	ETV2; TCF3 (directAnnotation).
ABHD13	taipale_tf_pairs__HOXB2_ELK3_RSCGGAAGTMRTTA_CAP	ELK3; HOXB2 (directAnnotation).
ABHD13	taipale_tf_pairs__ELK1_HOXA3_RSCGGTAATKR_CAP_repr	ELK1; HOXA3 (directAnnotation).
ABHD13	taipale_tf_pairs__HOXB2_ETV4_ACCGGAAATGAN_CAP	ETV4; HOXB2 (directAnnotation).
ABHD13	taipale_tf_pairs__ELF2_NATGCGGAAGTR_HT	ELF2 (directAnnotation).
ABHD13	taipale_tf_pairs__ELK1_EOMES_TNRCACCGGAAGN_CAP	ELK1; EOMES (directAnnotation).
ABHD13	taipale_tf_pairs__ELK1_HOXA1_RCCGGAAGTAATTA_HT	ELK1; HOXA1 (directAnnotation).
ABHD13	taipale_tf_pairs__HOXB2_ELF1_SMGGAAGTMRTTA_CAP	ELF1; HOXB2 (directAnnotation).
ABHD13	taipale_tf_pairs__ERF_FOXI1_RSCGGATGTTKWN_CAP_repr	ERF; FOXI1 (directAnnotation).
ABHD13	metacluster_198.7	AHR; ZBTB14; ZBTB14; ZBTB14 (directAnnotation).
ABHD13	taipale_tf_pairs__ERF_HES7_NCCGGAANNNNNNCACGYGNN_CAP_repr	ERF; HES7 (directAnnotation).
ABHD13	metacluster_19.7	GMEB1; GMEB2 (inferredBy_Orthology).
ABHD13	metacluster_138.2	ELF1; ELF2; ELF4; ELK1; ELK1; ELK1; ELK1; ELK3; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ELK4; ERF; ERG; ERG; ERG; ERG; ETS1; ETS1; ETS2; ETS2; ETV1; ETV1; ETV1; ETV2; ETV3; ETV4; ETV5; ETV5; FEV; FLI1; FLI1; GABPA; GABPA; KMT2B; SPDEF; SPDEF; SPDEF; ZBTB11; ZNF518A; ZNF580 (directAnnotation). ELF1; ELF2; ELF4; ELK1; ELK1; ELK3; ELK4; ERG; ETS1; ETS2; ETV1; ETV2; ETV3; ETV4; ETV5; FEV; FLI1; FLI1; GABPA; SPDEF; SPDEF (inferredBy_Orthology).
ABHD13	jaspar__MA1957.1	ELK1 (directAnnotation).

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Acts as a transcription factor

This table shows that this differential gene acts as a transcription factor.

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Acts as a drug target

This table shows that this differential gene acts as a drug target.

1	"Sun X, Zhang Y, Li H, Zhou Y, Shi S, Chen Z, He X, Zhang H, Li F, Yin J, Mou M, Wang Y, Qiu Y, Zhu F. DRESIS: the first comprehensive landscape of drug resistance information. Nucleic Acids Res. 2023 Jan 6;51(D1):D1263-D1275. doi: 10.1093/nar/gkac812. PMID: 36243960; PMCID: PMC9825618."
2	"Wishart DS, Feunang YD, Guo AC, Lo EJ, Marcu A, Grant JR, Sajed T, Johnson D, Li C, Sayeeda Z, Assempour N, Iynkkaran I, Liu Y, Maciejewski A, Gale N, Wilson A, Chin L, Cummings R, Le D, Pon A, Knox C, Wilson M. DrugBank 5.0: a major update to the DrugBank database for 2018. Nucleic Acids Res. 2018 Jan 4;46(D1):D1074-D1082. doi: 10.1093/nar/gkx1037. PMID: 29126136; PMCID: PMC5753335."