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lncRNA: ENSG00000280254

Summary for RP11-81A22.4

Gene summary

Gene information	Ensembl ID	ENSG00000280254
	Gene symbol	RP11-81A22.4
	Gene name
	HGNC
	Entrez ID
	Gene type	TEC
	Synonyms
	UniProtAcc

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Structure and expression level for RP11-81A22.4

AS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000280254	1.814096e+02	-1.617982e+00	2.959174e-01	-5.467680e+00	4.560000e-08	5.090000e-07	DOWN	GBM
ENSG00000280254	1.868849e+02	-1.486866e+00	2.837162e-01	-5.240683e+00	1.600000e-07	1.220000e-06	DOWN	CHOL
ENSG00000280254	1.835228e+02	-1.298102e+00	2.033500e-01	-6.383582e+00	1.730000e-10	1.040000e-09	DOWN	KICH
ENSG00000280254	2.195479e+02	1.556264e+00	4.610864e-01	3.375211e+00	7.375920e-04	9.334680e-03	UP	PCPG

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000280254	-6.236230e-01	6.673578e-11	KICH	1.034405e-09

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lncRNA-Protein interaction for RP11-81A22.4

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000078487	ZCWPW1	71.3	96.4475	Q9H0M4	Epi	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000170004	CHD3	117.29	90.5862	Q12873	Epi	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000166313	APBB1	88.56	91.3698	O00213	Epi	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000119638	NEK9	70.58	95.4629	Q8TD19	Epi	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000184402	SS18L1	37.38	92.0435	O75177	Epi	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000178028	DMAP1	26.76	92.2477	Q9NPF5	Epi	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000149929	HIRIP3	24.74	96.0528	Q9BW71	Epi	NA

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000130254	SAFB2	124.82	95.5152	Q14151	TF,RBP	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000099326	MZF1	96.6	94.9399	P28698	TF	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000165821	SALL2	71.12	94.966	Q9Y467	TF	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000166432	ZMAT1	51.54	96.8104	Q5H9K5	TF	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000180035	ZNF48	49.15	95.6112	Q96MX3	TF	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000180787	ZFP3	46.81	94.2501	Q96NJ6	TF	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000105708	ZNF14	40.05	94.1285	P17017	TF	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000177030	DEAF1	37.8	92.323	O75398	TF	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000221944	TIGD1	23.74	91.2088	Q96MW7	TF	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000185670	ZBTB3	21.61	95.0824	Q9H5J0	TF	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000154957	ZNF18	21.6	95.0286	P17022	TF	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000196378	ZNF34	20.38	96.3527	Q8IZ26	TF	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000250571	GLI4	15.86	90.3829	P10075	TF	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000176946	THAP4	14.76	94.1064	Q8WY91	TF	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000184436	THAP7	8.41	91.8298	Q9BT49	TF	NA

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID	LncRNA ENST ID	LncRNA Name	Protein Ensembl ID	Protein Name	CatRAPID Score	Lncpro Score	UniPortID	Gene Subtype	Public source
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000130254	SAFB2	124.82	95.4853	Q14151	TF,RBP	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000148296	SURF6	66.83	91.5208	O75683	RBP	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000100650	SRSF5	66.42	94.9906	Q13243	RBP	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000173914	RBM4B	61.98	92.4718	Q9BQ04	RBP	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000099622	CIRBP	53.32	92.0235	Q14011	RBP	NA
ENSG00000280254	ENST00000623798	RP11-81A22.4	ENSG00000089280	FUS	50.37	96.4126	P35637	RBP	NA

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lncRNA-DNA interaction for RP11-81A22.4

lncRNA targets the enhancer region and positively regulates the gene expression.

Only predicted by TDF

ARL16,TCEA2,ZSWIM9,ARFIP2,THAP4,PRPSAP2,DNAJC27,CIRBP,KIFC3,MZF1,C1orf56,PEBP1,DYNC2I2,SIRT3,CACFD1,SUGP2,PPP2R3B,HINT2,ACD,XAB2,MIEF2,TRAPPC12,PTPRS,SAFB2,HIRIP3,DEGS2,C6orf136,COA3,PMM1,INPP5K,SLC2A11,COG4,GKAP1,SPRN,MAPK8IP1,FAM218A,SUGP1,SPG7,SUSD4,NAA80,FAM104B,C19orf44,RNF167,ECHDC2,CYB5D2,ERAL1,CA11,MST1,RING1,SLC22A17,CBY1,WDR83,OSGEP,CTC1,GABPB1,CCDC149,PDZD4,RPAIN,MRPS11,ACYP1,MAP2K4,MIS12,DERL2,PGAP3,C3orf62,PNMA8A,CYSRT1,YJU2,BORCS6,MAPRE3,HDHD3,C22orf39,COQ6,DDX51,FUZ,PIGZ,CUL9,FBXW4,IPO13,UBE2O,MRPL57,ADHFE1,PAN2,IL17RC,FAM229A,LRTOMT,CCS,MOAP1,ZNF14,PPT2,ARFGAP2,DMAC2L,SEPSECS,HEXD,IFT122,DVL2,GAS8,SCNN1D,CCDC24,KAT14,KIF12,ZFP3,CYFIP2,PHYHD1,ABHD8,IQCC,ZFYVE28,TRMO,USP27X,GLI4,PRR3,FAM98C,NICN1,UBE2G2,IP6K2,PPOX,FNDC10,COX16,C20orf96,ADPRM,COG8,APBB1,WDR59,TMEM175,SPACA9,MRM3,MPP2,NAA38,TCTA,CCDC106,NEK9,FBXO44,EXD3,C17orf75,PPP1R13B,P4HTM,PATZ1,PCED1A,ELP5,BRF1,METTL16,RAB17,TTC8,UBOX5,PQBP1,H2BC21,ZNF48,GALT,TADA2A,DENND6B,PEX11G,CCHCR1,PRMT7,ZFYVE19,FAXDC2,NEK8,FIZ1,LTB4R,SERP2,HEMK1,CACNA1H,ROGDI,PCSK4,MED29,RAB11FIP3,FRS3,C2orf68,FBXL8,CASKIN2,CRMP1,MYL5,GSTA4,PSME3IP1,STK32C,SRR,UBXN11,HAGH,B9D1,SSBP3,PLXNB1,PPP1R26,ATPAF2,STON2,AMT,LRRC27,GLOD4,SPAG7,ATP5IF1,MAPK10,SPRYD4,ZBTB4,POMT1,WDR25,NLGN2,UBTF,ACADVL,MKS1,C1orf35,MARCHF9,NPRL2,ZCWPW1,KLHDC4,KLHDC1,EIPR1,ZC4H2,DCAKD,XPC,CLK3,TOM1L2,HDAC11,INCA1,VPS9D1,ZER1,GABBR1,USP11,SGSM3,MC1R,COQ4,DHRS12,ACBD4,CHD3,PLA2G6,ZBTB3,ENDOV,TMEM179,POLI,ELP6,TRAM1L1,ZNF34,ERMARD,KIAA0753,PRR36,VPS53,MTHFR,CDNF,HDAC10,DEAF1,HEXIM2,CHADL,SCRN2,RNF208,HSF4,ANKS3,NOXA1,UCK1,SMDT1,PIGQ,ANKRD54,SGSM2,PGAP4,MADD,CENPS,HDHD5,SPOP,GABRB3,RETREG3,TMUB2,FAM161B,ZMYM3,ABCD4,TRIM46,DPH1,PELP1,TNK1,NEIL1,RPH3AL,ADAMTS13,VPS33B,GRIPAP1,KPTN,RNF215,GIN1,ABHD14A,LUC7L,KLHL22,WDR6,TMEM25,COA5,C14orf93,LRSAM1,RETREG2,NEURL4,XPA,PCBD2,APBB3,CNTROB,WBP1,WDR37,TAF6L,DCTN3,C16orf86,RRNAD1,ADGRL1,KAT8,ZSWIM7,TRIM39,SLC25A11,MPDU1,RP11-523H20.5,KIAA0895L,HSD17B8,OSCP1,MUTYH,DCAF8,OBSL1,CACTIN,CINP,IFT27,RECQL5,LRRC75B,SWSAP1,TBC1D17,SENP3,ERCC2,NT5C3B,MED31,DLG4,C1orf216,CENPT,PACS2,SHC2,CFAP410,VAMP2,DTNB,DBP,RBM4B,TECPR2,DNAJB2,TMEM99,ANAPC2,TAF1C,SURF6,DCXR,C17orf107,GAMT,CXXC1,SPHK2,MRNIP,SS18L1,TTLL1,GNB5,PARD6A,GSTM2,ARVCF,LIAS,NINL,SDR39U1,IFT46,CDAN1,HAUS4,FAM216A,HTRA2,LRRC29,WDR31,FAM228B,TIGD1,GPS2,PEMT,NCBP3,SALL2,TTC32,ZMAT1,SPATA33,ZNF18,KLHDC3,BLMH,DUSP28,RBM5,BOLA1,ULK2,YPEL3,RXRB,NDUFV3,DGCR6L,TSC1,TMEM125,USP20,MRFAP1L1

Exist in public source

lncRNA targets the promoter region and positively regulates the gene expression.

Only predicted by TDF

DCAF8,SGSM3,C22orf39,SIRT4,LDOC1,APITD1,PEMT,UBTF,ZNF18,ROGDI,COG4,KIZ,C20orf196,ZMAT1,CA11,PEX11G,PGPEP1,COX16,TAF1C,TMEM99,KLHL22,EID2B,PDZD4,OXLD1,CTC1,HDHD3,TMEM246,HEMK1,C1orf56,HTRA2,THAP4,NCBP3,KLHDC4,NICN1,PSMB6,C19orf44,ZER1,TIGD1,ZNF14,THAP7,GPANK1,COQ6,MAPRE3,VPS37D,LRRC27,CYFIP2,ZC3H6,OSCP1,TCEAL2,GSTA4,VPS33B,LUC7L,RNF167,WDR31,SDR39U1,C14orf79,ZMYM3,MZF1,HINT2,VAMP2,C3orf62,ZBTB4,FAM218A,INPP5K,GAMT,CXXC1,TRMO,C17orf75,UCK1,MYL5,SEPSECS,TIMM22,HLF,MARCH9,NT5M,ZSWIM7,C2orf68,GLTPD2,GRIPAP1,XPC,MOAP1,KPTN,ELAC1,NINL,SAT2,MAGEF1,FBXL8,DPH1,ATPIF1,TSSC1,ABCD4,ZNF48,HSF4,FUZ,ING5,WDR13,ADGRL1,PNMAL1,PIGV,POMT1,CAMSAP3,SLC25A11,CBY1,FAM161B,MPI,DERL2,ARIH2OS,TOM1L2,PELP1,PCBD2,STK32C,NAA38,ZFP3,MIS12,ERMARD,MRFAP1L1,CIRBP,CDAN1

Exist in public source

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-81A22.4

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

FNDC3B,TWF1,ERGIC2,PICALM,CALU,LIMS1,TUBA1C

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

ORF mutation

-lncRNA and exonskipping events are negatively correlated.

LncRNA Ensembl ID

LncRNA ENST ID

Exon ID

Skipped Exon

ndG

Gene name with skipped exon

TransID with skipped exon

LOF

lncRNA targets by miRNA.

LncRNA Ensembl ID	miRNA ID	LncRNA ENST ID	Binding site in lncRNA	Score	Energy	Align Len	Public source
ENSG00000280254	hsa-mir-22	ENST00000623798	chr17:4788984-4789058	199.00	-90.67	81	NA
ENSG00000280254	hsa-mir-22	ENST00000623798	chr17:4788486-4788570	194.00	-70.02	84	NA
ENSG00000280254	hsa-mir-22	ENST00000623798	chr17:4788622-4788706	175.00	-68.90	87	NA
ENSG00000280254	hsa-mir-22	ENST00000623798	chr17:4787963-4788047	173.00	-91.33	85	NA
ENSG00000280254	hsa-mir-22	ENST00000623798	chr17:4788843-4788926	167.00	-84.67	79	NA
ENSG00000280254	hsa-mir-22	ENST00000623798	chr17:4787080-4787162	164.00	-83.83	88	NA
ENSG00000280254	hsa-mir-22	ENST00000623798	chr17:4788194-4788276	161.00	-73.99	85	NA
ENSG00000280254	hsa-mir-22	ENST00000623798	chr17:4789061-4789149	158.00	-76.63	77	NA
ENSG00000280254	hsa-mir-22	ENST00000623798	chr17:4787552-4787641	154.00	-88.06	89	NA
ENSG00000280254	hsa-mir-22	ENST00000623798	chr17:4787222-4787298	152.00	-77.54	83	NA
ENSG00000280254	hsa-mir-22	ENST00000623798	chr17:4787680-4787779	151.00	-86.25	92	NA
ENSG00000280254	hsa-mir-22	ENST00000623798	chr17:4787860-4787938	149.00	-59.79	84	NA
ENSG00000280254	hsa-mir-22	ENST00000623798	chr17:4788287-4788364	147.00	-74.88	72	NA

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Variants for RP11-81A22.4

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID	PC Gene ID	PC Gene Name	Positive correlated cancers	Cancer with PC gene up-regulation	Cancer with PC gene down-regulation
ENSG00000280254	ENSG00000063180	CA11	BRCA,CHOL,ESCA,GBM,KICH,PAAD,PCPG	PCPG	GBM
ENSG00000280254	ENSG00000065559	MAP2K4	BRCA,ESCA,GBM,KICH,PAAD		GBM
ENSG00000280254	ENSG00000090238	YPEL3	BRCA,GBM,HNSC,KICH,KIRP,LGG,LUAD		GBM
ENSG00000280254	ENSG00000108641	B9D1	BRCA,KICH,KIRP,PAAD,PRAD,THCA		KICH
ENSG00000280254	ENSG00000115137	DNAJC27	BRCA,GBM,KICH,KIRC,LUSC,PAAD		GBM
ENSG00000280254	ENSG00000116885	OSCP1	BRCA,KICH,KIRC,PAAD,PRAD,THCA		KICH
ENSG00000280254	ENSG00000121310	ECHDC2	BRCA,CHOL,KICH,KIRC,KIRP,LUAD,PAAD,SARC,THCA		CHOL,KICH
ENSG00000280254	ENSG00000124839	RAB17	BRCA,CHOL,KICH,KIRC,LUAD,PAAD,THCA		CHOL
ENSG00000280254	ENSG00000129946	SHC2	BRCA,HNSC,LGG,LUSC,PAAD,PCPG	PCPG
ENSG00000280254	ENSG00000130005	GAMT	BRCA,ESCA,KICH,PAAD,THCA,THYM		KICH
ENSG00000280254	ENSG00000132535	DLG4	BRCA,GBM,KICH,LUSC,PAAD,PCPG	PCPG	GBM
ENSG00000280254	ENSG00000133460	SLC2A11	BRCA,CHOL,GBM,KIRC,KIRP,LGG,LUAD,LUSC,PAAD,SARC		GBM
ENSG00000280254	ENSG00000145029	NICN1	BRCA,GBM,KICH,KIRC,KIRP,LGG,LUAD,PAAD,PRAD,SARC,THCA		GBM
ENSG00000280254	ENSG00000148814	LRRC27	BRCA,GBM,KIRP,LGG,THCA		GBM
ENSG00000280254	ENSG00000149582	TMEM25	BRCA,GBM,KICH,KIRC,PAAD,PCPG,SARC		GBM
ENSG00000280254	ENSG00000151778	SERP2	BRCA,KICH,KIRC,LGG,PAAD,PCPG	PCPG	KICH
ENSG00000280254	ENSG00000156050	FAM161B	BRCA,GBM,KICH,KIRC,PAAD		GBM,KICH
ENSG00000280254	ENSG00000159239	RP11-523H20.5	BRCA,KICH,KIRC,KIRP,PAAD,PCPG,PRAD	PCPG	KICH
ENSG00000280254	ENSG00000160445	ZER1	BRCA,CESC,GBM,KIRC,KIRP,PAAD,THYM		GBM
ENSG00000280254	ENSG00000162572	SCNN1D	BRCA,CHOL,GBM,KIRP,LGG,PAAD		CHOL
ENSG00000280254	ENSG00000165943	MOAP1	BRCA,GBM,KICH,KIRC,LUAD,LUSC,PAAD,SARC		GBM
ENSG00000280254	ENSG00000168350	DEGS2	BRCA,KICH,KIRC,KIRP,THCA		KICH
ENSG00000280254	ENSG00000170004	CHD3	BRCA,GBM,KICH,LGG,LUAD,PCPG,THCA		GBM
ENSG00000280254	ENSG00000173531	MST1	BRCA,GBM,KICH,KIRP,LGG,PAAD,SARC		KICH
ENSG00000280254	ENSG00000174292	TNK1	BRCA,KICH,KIRC,KIRP,THCA		KICH
ENSG00000280254	ENSG00000174599	TRAM1L1	BRCA,KICH,KIRC,LGG,PAAD,THCA		KICH
ENSG00000280254	ENSG00000175662	TOM1L2	BRCA,GBM,KICH,KIRC,LGG,LUAD,PAAD,THCA,THYM		GBM
ENSG00000280254	ENSG00000181513	ACBD4	BRCA,CHOL,GBM,KICH,KIRC,KIRP,LUAD,LUSC,PAAD,PRAD,SARC,THCA		CHOL,KICH
ENSG00000280254	ENSG00000185267	CDNF	BRCA,CHOL,KIRC,KIRP,LGG,THCA		CHOL
ENSG00000280254	ENSG00000197776	KLHDC1	BRCA,GBM,KICH,LGG,PAAD,SARC,THCA		GBM
ENSG00000280254	ENSG00000204228	HSD17B8	BRCA,CHOL,KICH,KIRC,KIRP,THCA,THYM		CHOL
ENSG00000280254	ENSG00000205593	DENND6B	BRCA,GBM,KICH,KIRP,PAAD,PRAD		GBM,KICH
ENSG00000280254	ENSG00000215041	NEURL4	BRCA,GBM,KICH,KIRC,KIRP,LGG,LUAD,LUSC,PAAD,PCPG,SARC,THCA		GBM
ENSG00000280254	ENSG00000219626	FAM228B	BRCA,KICH,KIRP,LGG,LUSC,PAAD,SARC,THCA		KICH
ENSG00000280254	ENSG00000220205	VAMP2	BRCA,CESC,CHOL,GBM,HNSC,KICH,KIRC,KIRP,LUAD,LUSC,PAAD		GBM
ENSG00000280254	ENSG00000067836	ROGDI	CESC,GBM,KIRP,LUAD,PAAD,PRAD,SARC,THYM		GBM
ENSG00000280254	ENSG00000083290	ULK2	CHOL,GBM,KICH,PAAD,PCPG,SARC		GBM
ENSG00000280254	ENSG00000089220	PEBP1	CHOL,KICH,KIRC,PAAD,THCA		CHOL
ENSG00000280254	ENSG00000109618	SEPSECS	CHOL,KICH,KIRC,PAAD,PCPG,SARC,THCA		CHOL
ENSG00000280254	ENSG00000127220	ABHD8	CHOL,GBM,KICH,PAAD,PCPG		GBM
ENSG00000280254	ENSG00000142686	C1orf216	CHOL,GBM,KICH,SARC,THYM		GBM
ENSG00000280254	ENSG00000161395	PGAP3	CHOL,KICH,KIRC,KIRP,LGG		CHOL
ENSG00000280254	ENSG00000169992	NLGN2	CHOL,GBM,KICH,KIRP,LGG,PCPG		GBM
ENSG00000280254	ENSG00000170899	GSTA4	CHOL,ESCA,KICH,KIRC,KIRP,LGG,PAAD		CHOL,KICH
ENSG00000280254	ENSG00000178026	LRRC75B	CHOL,KICH,KIRP,LGG,LUAD,SARC,THCA		KICH
ENSG00000280254	ENSG00000183248	PRR36	CHOL,GBM,LGG,PAAD,PCPG	PCPG	GBM
ENSG00000280254	ENSG00000184402	SS18L1	CHOL,GBM,LGG,PAAD,PCPG		CHOL,GBM
ENSG00000280254	ENSG00000204681	GABBR1	CHOL,GBM,KICH,PAAD,SARC		GBM
ENSG00000280254	ENSG00000228594	FNDC10	CHOL,GBM,HNSC,PRAD,THCA		GBM
ENSG00000280254	ENSG00000143502	SUSD4	ESCA,KICH,KIRC,PAAD,THYM		KICH
ENSG00000280254	ENSG00000047056	WDR37	GBM,KICH,LGG,PAAD,THCA		GBM
ENSG00000280254	ENSG00000055163	CYFIP2	GBM,KICH,KIRC,PAAD,SARC		GBM,KICH
ENSG00000280254	ENSG00000067840	PDZD4	GBM,LGG,PAAD,PCPG,SARC	PCPG	GBM
ENSG00000280254	ENSG00000068400	GRIPAP1	GBM,LGG,PAAD,PCPG,SARC		GBM
ENSG00000280254	ENSG00000069966	GNB5	GBM,KICH,PAAD,SARC,THYM		GBM
ENSG00000280254	ENSG00000084764	MAPRE3	GBM,LUSC,PAAD,PCPG,THCA,THYM	PCPG	GBM
ENSG00000280254	ENSG00000088808	PPP1R13B	GBM,KIRC,LUAD,PCPG,THCA		GBM
ENSG00000280254	ENSG00000102226	USP11	GBM,LGG,PAAD,SARC,THCA		GBM
ENSG00000280254	ENSG00000108852	MPP2	GBM,KICH,LUSC,PAAD,PCPG,SARC,THCA	PCPG	GBM
ENSG00000280254	ENSG00000109339	MAPK10	GBM,KICH,KIRC,PAAD,THCA		GBM,KICH
ENSG00000280254	ENSG00000117408	IPO13	GBM,KICH,PAAD,THCA,THYM		GBM
ENSG00000280254	ENSG00000119227	PIGZ	GBM,LGG,LUSC,PAAD,PRAD,SARC		GBM
ENSG00000280254	ENSG00000121653	MAPK8IP1	GBM,KIRC,KIRP,PAAD,THCA		GBM
ENSG00000280254	ENSG00000132879	FBXO44	GBM,KIRP,PAAD,THCA,THYM		GBM
ENSG00000280254	ENSG00000135924	DNAJB2	GBM,KICH,KIRP,PAAD,PRAD,THCA,THYM		GBM
ENSG00000280254	ENSG00000136878	USP20	GBM,KIRC,KIRP,LGG,PAAD,THCA,THYM		GBM
ENSG00000280254	ENSG00000137218	FRS3	GBM,KICH,LGG,PAAD,THCA		GBM
ENSG00000280254	ENSG00000138101	DTNB	GBM,KIRP,PCPG,PRAD,THCA	PCPG	GBM
ENSG00000280254	ENSG00000140022	STON2	GBM,KICH,KIRP,PAAD,THCA		KICH
ENSG00000280254	ENSG00000141252	VPS53	GBM,KICH,KIRC,LGG,PAAD,PCPG		GBM
ENSG00000280254	ENSG00000147576	ADHFE1	GBM,KICH,KIRC,KIRP,SARC,THCA		GBM
ENSG00000280254	ENSG00000148225	WDR31	GBM,KICH,KIRC,PAAD,THCA		KICH
ENSG00000280254	ENSG00000148356	LRSAM1	GBM,KIRC,KIRP,LGG,PAAD,THCA,THYM		GBM
ENSG00000280254	ENSG00000159733	ZFYVE28	GBM,KICH,KIRC,PAAD,THYM		GBM
ENSG00000280254	ENSG00000159761	C16orf86	GBM,KICH,KIRC,KIRP,LGG,PAAD,THCA		KICH
ENSG00000280254	ENSG00000163517	HDAC11	GBM,KIRC,KIRP,PAAD,SARC,THCA,THYM		GBM
ENSG00000280254	ENSG00000163913	IFT122	GBM,KICH,KIRC,PAAD,THCA		KICH
ENSG00000280254	ENSG00000164050	PLXNB1	GBM,KICH,KIRC,KIRP,LUAD,PAAD,SARC		KICH
ENSG00000280254	ENSG00000165152	PGAP4	GBM,KICH,KIRC,LGG,PAAD		GBM
ENSG00000280254	ENSG00000165699	TSC1	GBM,KIRC,LGG,PAAD,THCA		GBM
ENSG00000280254	ENSG00000165752	STK32C	GBM,KICH,LGG,PAAD,THCA		GBM
ENSG00000280254	ENSG00000166206	GABRB3	GBM,LGG,PAAD,PCPG,THCA	PCPG	GBM
ENSG00000280254	ENSG00000166313	APBB1	GBM,KICH,KIRC,LGG,PAAD		GBM
ENSG00000280254	ENSG00000170271	FAXDC2	GBM,KICH,KIRC,SARC,THCA		GBM
ENSG00000280254	ENSG00000175931	UBE2O	GBM,LGG,PAAD,PCPG,THCA		GBM
ENSG00000280254	ENSG00000179364	PACS2	GBM,KIRC,KIRP,PAAD,PCPG		GBM
ENSG00000280254	ENSG00000181982	CCDC149	GBM,KICH,KIRC,PAAD,PCPG,THCA	PCPG	GBM
ENSG00000280254	ENSG00000182013	PNMA8A	GBM,KICH,PAAD,PCPG,THCA		GBM,KICH
ENSG00000280254	ENSG00000185453	ZSWIM9	GBM,KIRP,PAAD,PCPG,SARC,THCA	PCPG	GBM
ENSG00000280254	ENSG00000196422	PPP1R26	GBM,KIRC,LGG,PAAD,SARC		GBM
ENSG00000280254	ENSG00000196557	CACNA1H	GBM,KICH,PAAD,PCPG,THCA		GBM,KICH
ENSG00000280254	ENSG00000196663	TECPR2	GBM,KICH,KIRC,PAAD,PCPG		GBM
ENSG00000280254	ENSG00000203772	SPRN	GBM,KIRP,LGG,LIHC,PAAD,THCA		GBM
ENSG00000280254	ENSG00000204564	C6orf136	GBM,KIRP,LGG,PAAD,THCA		GBM
ENSG00000280254	ENSG00000212864	RNF208	GBM,HNSC,KIRP,LGG,PAAD,SARC,THYM		GBM
ENSG00000280254	ENSG00000273820	USP27X	GBM,KICH,LGG,LUSC,PAAD,SARC		GBM
ENSG00000280254	ENSG00000072832	CRMP1	KICH,LGG,LUSC,PAAD,PCPG,THYM	PCPG
ENSG00000280254	ENSG00000105426	PTPRS	KICH,LGG,PAAD,PCPG,THCA		KICH
ENSG00000280254	ENSG00000124006	OBSL1	KICH,KIRP,LGG,LUAD,PAAD,THCA		KICH
ENSG00000280254	ENSG00000130770	ATP5IF1	KICH,KIRP,PAAD,PRAD,THCA,THYM		KICH
ENSG00000280254	ENSG00000136883	KIF12	KICH,KIRC,KIRP,PAAD,THCA		KICH
ENSG00000280254	ENSG00000140859	KIFC3	KICH,KIRC,KIRP,LUAD,THCA		KICH
ENSG00000280254	ENSG00000158062	UBXN11	KICH,KIRP,PAAD,PRAD,THCA		KICH
ENSG00000280254	ENSG00000165698	SPACA9	KICH,KIRC,KIRP,PAAD,THCA,THYM		KICH
ENSG00000280254	ENSG00000175279	CENPS	KICH,KIRP,PAAD,PRAD,THCA		KICH
ENSG00000280254	ENSG00000179178	TMEM125	KICH,KIRC,KIRP,LUAD,THCA		KICH
ENSG00000280254	ENSG00000182518	FAM104B	KICH,KIRP,PAAD,PCPG,PRAD,THCA,THYM		KICH
ENSG00000280254	ENSG00000139266	MARCHF9	KIRC,PAAD,PCPG,PRAD,THCA	PCPG

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID	TF ID	TF Name	PCgene ID	PCgene Name	Number of Cancer	Canaer Types
ENSG00000280254	ENSG00000250571	GLI4	ENSG00000154957	ZNF18	6	CHOL,GBM,KIRP,LUAD,PCPG,THCA
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000103168	TAF1C	5	GBM,KICH,KIRP,LUAD,THCA
ENSG00000280254	ENSG00000250571	GLI4	ENSG00000204237	OXLD1	5	HNSC,KIRP,LGG,PCPG,THCA
ENSG00000280254	ENSG00000099326	MZF1	ENSG00000178971	CTC1	5	BRCA,GBM,KICH,LUAD,PAAD
ENSG00000280254	ENSG00000130254	SAFB2	ENSG00000178971	CTC1	5	GBM,KICH,KIRC,KIRP,PAAD
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000178971	CTC1	7	BRCA,GBM,KICH,KIRP,LUAD,PAAD,PCPG
ENSG00000280254	ENSG00000165821	SALL2	ENSG00000178971	CTC1	5	BRCA,GBM,KICH,PAAD,PCPG
ENSG00000280254	ENSG00000180787	ZFP3	ENSG00000178971	CTC1	5	GBM,KICH,KIRC,PAAD,PCPG
ENSG00000280254	ENSG00000250571	GLI4	ENSG00000114735	HEMK1	6	GBM,KIRP,LGG,LUAD,SARC,THCA
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000074356	NCBP3	5	GBM,KICH,LUSC,PAAD,PCPG
ENSG00000280254	ENSG00000250571	GLI4	ENSG00000104731	KLHDC4	5	GBM,KIRP,LGG,LUAD,THCA
ENSG00000280254	ENSG00000165821	SALL2	ENSG00000145029	NICN1	5	BRCA,KICH,KIRC,PAAD,SARC
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000108523	RNF167	8	BRCA,CESC,KICH,KIRP,LUSC,PAAD,PCPG,THCA
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000140104	CLBA1	6	BRCA,KICH,KIRP,LUAD,PAAD,THCA
ENSG00000280254	ENSG00000165821	SALL2	ENSG00000147130	ZMYM3	5	GBM,KICH,KIRC,PAAD,PCPG
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000099326	MZF1	5	GBM,KICH,LUAD,PAAD,THCA
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000188315	C3orf62	6	BRCA,KICH,KIRP,LUAD,PAAD,THCA
ENSG00000280254	ENSG00000165821	SALL2	ENSG00000174282	ZBTB4	5	BRCA,GBM,KICH,KIRC,PAAD
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000132376	INPP5K	8	BRCA,CESC,ESCA,GBM,KICH,KIRP,PAAD,PCPG
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000154832	CXXC1	5	CHOL,KICH,KIRP,PAAD,THCA
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000177370	TIMM22	5	KICH,KIRP,PAAD,PCPG,THCA
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000205309	NT5M	6	CESC,KICH,LUSC,PAAD,PCPG,THCA
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000214941	ZSWIM7	5	BRCA,KICH,KIRP,LUAD,THCA
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000168887	C2orf68	5	CHOL,GBM,KICH,KIRP,THCA
ENSG00000280254	ENSG00000185670	ZBTB3	ENSG00000168887	C2orf68	5	CHOL,GBM,KIRP,LGG,PCPG
ENSG00000280254	ENSG00000250571	GLI4	ENSG00000168887	C2orf68	5	CHOL,GBM,KIRP,LGG,THCA
ENSG00000280254	ENSG00000165821	SALL2	ENSG00000154767	XPC	5	BRCA,GBM,KICH,KIRC,PAAD
ENSG00000280254	ENSG00000165821	SALL2	ENSG00000165943	MOAP1	5	BRCA,KICH,KIRC,PAAD,SARC
ENSG00000280254	ENSG00000250571	GLI4	ENSG00000135722	FBXL8	5	HNSC,KIRP,LUAD,SARC,THCA
ENSG00000280254	ENSG00000099326	MZF1	ENSG00000108963	DPH1	5	BRCA,GBM,KICH,LUAD,PAAD
ENSG00000280254	ENSG00000130254	SAFB2	ENSG00000108963	DPH1	5	GBM,KICH,KIRC,KIRP,PAAD
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000108963	DPH1	8	BRCA,CHOL,GBM,KICH,KIRP,LUAD,LUSC,PAAD
ENSG00000280254	ENSG00000165821	SALL2	ENSG00000156050	FAM161B	5	BRCA,GBM,KICH,KIRC,PAAD
ENSG00000280254	ENSG00000250571	GLI4	ENSG00000141456	PELP1	5	GBM,KIRP,LGG,PCPG,THCA
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000180787	ZFP3	5	CESC,GBM,PAAD,PCPG,THCA
ENSG00000280254	ENSG00000165821	SALL2	ENSG00000180787	ZFP3	5	GBM,KICH,KIRC,PAAD,PCPG
ENSG00000280254	ENSG00000154957	ZNF18	ENSG00000167842	MIS12	5	BRCA,KICH,KIRP,PAAD,THCA
ENSG00000280254	ENSG00000185670	ZBTB3	ENSG00000099622	CIRBP	5	GBM,KIRP,LGG,PCPG,PRAD
ENSG00000280254	ENSG00000250571	GLI4	ENSG00000099622	CIRBP	6	GBM,HNSC,KIRP,LGG,PCPG,THCA

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID	LncRNA ENST ID	PC Gene Name	PC Gene ID	PC ENST ID	dG	nDG	Cancer with PC gene up-regulation	Cancer with PC gene Down-regulation
ENSG00000280254	ENST00000623798	TUBA1C	ENSG00000167553	ENST00000549818	-0.1445	1200	GBM	-
ENSG00000280254	ENST00000623798	LIMS1	ENSG00000169756	ENST00000414829	-0.3292	1921	GBM,KICH	-
ENSG00000280254	ENST00000623798	TWF1	ENSG00000151239	ENST00000548315	-0.2017	1877	GBM,KICH	-
ENSG00000280254	ENST00000623798	PICALM	ENSG00000073921	ENST00000532603	-0.1035	1869	KICH	-
ENSG00000280254	ENST00000623798	PICALM	ENSG00000073921	ENST00000356360	-0.1900	1903	KICH	-
ENSG00000280254	ENST00000623798	PICALM	ENSG00000073921	ENST00000529016	-0.7000	343	KICH	-
ENSG00000280254	ENST00000623798	PICALM	ENSG00000073921	ENST00000526961	-1.6450	61	KICH	-
ENSG00000280254	ENST00000623798	FNDC3B	ENSG00000075420	ENST00000423424	-0.1471	1435	GBM	PCPG
ENSG00000280254	ENST00000623798	FNDC3B	ENSG00000075420	ENST00000416957	-1.6050	309	GBM	PCPG

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID	lncRNA-miRNA-mRNA	Cancer Types
ENSG00000280254	RP11-81A22.4,hsa-mir-22,WDR33	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,CRMP1	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,PHF2	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,COIL	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,YTHDC1	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,PRR14	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,C2orf68	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,ZNF7	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,NAA16	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,PHC1	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,PAXBP1	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,PAGR1	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,TIA1	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,DPF2	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,EDRF1	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,SBK1	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,RBMX	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,FBXO46	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,RBM14	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,PCIF1	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,DGCR8	PCPG,KICH,LGG,SARC,KIRP
ENSG00000280254	RP11-81A22.4,hsa-mir-22,CTDSPL2	PCPG,KICH,LGG,SARC,KIRP

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000280254.1	ENST00000623798.1	80	6	248

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential