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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000279799

Summary for AC006077.3

check button Gene summary

Gene informationEnsembl ID

ENSG00000279799

Gene symbol

AC006077.3

Gene name
HGNC
Entrez ID
Gene typeTEC
Synonyms
UniProtAcc

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Structure and expression level for AC006077.3

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002797992.432484e+012.057828e+004.600735e-014.472825e+007.720000e-064.270000e-05UPCHOL
ENSG000002797992.734881e+011.270205e+002.955747e-014.297407e+001.730000e-051.124340e-04UPBLCA
ENSG000002797992.415362e+011.125134e+002.066384e-015.444939e+005.180000e-082.580000e-07UPUCEC

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002797995.840883e-012.529023e-05CHOL1.194892e-04

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lncRNA-Protein interaction for AC006077.3

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for AC006077.3

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for AC006077.3

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
TBC1D14,CNOT1,TRAF6,IDH3A,NF1,FAM168B,TNS3,NEK4,DIABLO,TXNDC5,QKI,DENND4C,SLC30A6,VPS4B,UHRF1BP1L,MYH9,SUSD6,RNF123,KDM3B,FCF1,AIDA,NT5C2,BECN1,RDX,DUSP3,HIPK1,KPNA6,RNF40,ATXN1L,FAM104A,SMCR8,UBR1,SEPTIN10,TRAPPC10,ACTR3,GNL3L,PCDHGC3,PPP1R12A,EAF1,PIP4K2C,IL1R1,PTPN11,SCYL2,TOX4,TBC1D15,ITGB1,EDEM1,BZW1,ARHGAP21,NEDD1,C11orf58,HECTD1,ADGRL2,MANEA,SLAIN2,ANKFY1,CDV3,DNAJC14,PCBP1,ARIH1,PSMC1,PUM1,VPS13B,CAP1,SEC24B,CLTC,ATRN,ITPRIPL2,MAN1A2,NCOA1,PCYOX1,ATP2A2,MRPL19,VGLL4,MACF1,SH3GLB1,NBR1,CTNNB1,ATP11B,ZC3H13,TOR1AIP1,LZIC,PKD2,PDPK1,M6PR,ATP2C1,PHF3,WWP1,SNX29,KTN1,OSBP,APAF1,BBX,CPEB4,TAF1,ILK,CDYL,STRN,TP53BP1,VPS37A,ERLIN2,PCNX1,SURF4,USP32,SH3BP5,SEC24D,VCL,KIDINS220,SGCB,IQGAP1,DYNC1I2,G3BP1,CDC27,DOCK7,ACOX1,SMARCA2,CLIP1,CLCN3,STAT3,SNTB2,CORO1C,SDCBP,SLC25A24,FBXW11,API5,ARNT,GANAB,SEC23A,GIT2,STK24,NCOA2,TMEM43,SLC25A25,UBE3C,TWF1,SNAP23,MKLN1,LUZP1,DDX3X,MPDZ,ASXL2,ROCK1,G3BP2,RNF169,MAPK1,RB1CC1,GOLGA7,UBR5,KDM1B,SMAD1,POLR2B,CNIH1,COPB2,FAM168A,TBC1D2B,MYCBP2,LPCAT3,SSR1,SPPL2A,NIPA2,ZFAND3,MYOF,ACVR1,SRFBP1,TANGO6,TPM4,PDLIM5,UEVLD,CDK17,ASH1L,DYNC1LI2,KBTBD4,BRPF3,YAP1,APP,MFSD1,ARL1,FOXN3,CERT1,NPTN,RAP1B,PTPN9,TMEM131,SSH1,OSBPL8,XRN1,SMG6,NCOA4,SF3A1,MED13L,SEPTIN2,KLHL5,BCKDHB,NUP98,BCL9L,ABHD5,IGF2R,LYSMD3,AZI2,ST13,TAF1B,ASAP1,ACTR2,SYNJ1,VAMP7,TRIP12,TRAM2,GTF2A1,GOLGA4,ABCA1,HMGXB4,TNPO1,NSF,SEC23B,PAIP2,PPP2CB,KIF2A,MED1,TFIP11,SOS1,EIF3L,TGOLN2,SNX4,HBP1,MORC3,EIF4G2,HPS5,NEK7,C21orf91,CSNK1A1,SLC30A5,YTHDF3,NAA50,CUL2,CAB39,PRKAR1A,WAC,BIRC6,ACADM,SEC31A,BACH1,MOSPD2,CYFIP1,AFF1,MIEF1,UGGT1,ABCE1,TAF2,TMEM184C,NSRP1,MRTFB,GGCX,PICALM,DENND5A,TEX2,RALB,FAM114A2,EVC,SNX18,F2R,ITFG1,SRRD,SLC30A7,FEM1B,CPSF2,ARCN1,FNDC3B,ATF1,SEC24C,HAUS2,CCNK,LATS1,NEMF,CTDSP2,AFAP1,ZHX1,FYCO1,ARFGAP3,GNA12,MCFD2,SPOPL,NDUFS1,SDAD1,NOMO2,PGM2,RAB6A
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000279799ENST00000623591exon_skip_430601chr4:82842139-82842481-36.55-0.1125SEC31AENST00000355196,ENST00000395310,ENST00000448323In-frame
ENSG00000279799ENST00000623591exon_skip_44998chr10:110132304-110132400-9.81-0.1557ADD3ENST00000356080In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000279799ENST00000623591exon_skip_41813chr10:68337857-68337996-20.49-0.2227HNRNPH3ENST00000265866Frame-shift
ENSG00000279799ENST00000623591exon_skip_53559chr10:101793912-101793998-11.94-0.2253OGAENST00000361464Frame-shift
ENSG00000279799ENST00000623591exon_skip_87733chr12:120571190-120571291-24.15-0.2597RNF10ENST00000325954Frame-shift
ENSG00000279799ENST00000623591exon_skip_92074chr12:50142052-50142110-6.78-0.2825CERS5ENST00000317551Frame-shift
ENSG00000279799ENST00000623591exon_skip_95407chr12:95040475-95040597-15.09-0.1279NR2C1ENST00000333003Frame-shift
ENSG00000279799ENST00000623591exon_skip_97655chr12:120579773-120579923-10.76-0.1251POP5ENST00000357500In-frame
ENSG00000279799ENST00000623591exon_skip_152672chr17:42540949-42541206-30.76-0.1577NAGLUENST00000225927Frame-shift
ENSG00000279799ENST00000623591exon_skip_290158chr17:42953723-42953778-10.08-0.5040AARSD1ENST00000427569Frame-shift
ENSG00000279799ENST00000623591exon_skip_356108chr20:34740362-34743341-45.06-0.1121NCOA6ENST00000359003,ENST00000374796In-frame
ENSG00000279799ENST00000623591exon_skip_371367chr3:9697710-9697866-19.13-0.1438MTMR14ENST00000296003In-frame
ENSG00000279799ENST00000623591exon_skip_377198chr3:123130479-123130616-37.80-0.3231PDIA5ENST00000316218Frame-shift
ENSG00000279799ENST00000623591exon_skip_380242chr3:186784961-186785101-19.08-0.1800EIF4A2ENST00000323963Frame-shift
ENSG00000279799ENST00000623591exon_skip_382458chr3:38131595-38131638-11.06-0.2911ACAA1ENST00000333167Frame-shift
ENSG00000279799ENST00000623591exon_skip_387016chr3:121788283-121788432-15.75-0.1079IQCB1ENST00000310864Frame-shift
ENSG00000279799ENST00000623591exon_skip_430434chr4:82356536-82356683-13.76-0.2752HNRNPDENST00000313899In-frame
ENSG00000279799ENST00000623591exon_skip_442657chr5:74730259-74730398-16.63-0.1352GFM2ENST00000296805,ENST00000509430Frame-shift
ENSG00000279799ENST00000623591exon_skip_445390chr5:150403120-150403312-32.85-0.2147CD74ENST00000009530In-frame
ENSG00000279799ENST00000623591exon_skip_470226chr7:103307595-103307708-11.01-0.1327PMPCBENST00000249269Frame-shift
ENSG00000279799ENST00000623591exon_skip_476549chr7:76013741-76013887-21.55-0.2134STYXL1ENST00000248600,ENST00000359697,ENST00000431581Frame-shift
ENSG00000279799ENST00000623591exon_skip_511212chrX:71555189-71555385-22.74-0.1404OGTENST00000373719Frame-shift
ENSG00000279799ENST00000623591exon_skip_514339chrX:23713134-23713208-9.45-0.2554ACOT9ENST00000336430Frame-shift

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for AC006077.3

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000279799ENST00000623591ROCK1ENSG00000067900ENST00000399799-0.11311-BLCA
ENSG00000279799ENST00000623591BZW1ENSG00000082153ENST00000452790-0.274015-CHOL
ENSG00000279799ENST00000623591CNIH1ENSG00000100528ENST00000556113-0.16311-CHOL
ENSG00000279799ENST00000623591SEC23AENSG00000100934ENST00000548032-0.1006173-CHOL,BLCA,UCEC
ENSG00000279799ENST00000623591SEC23AENSG00000100934ENST00000557280-0.13871-CHOL,BLCA,UCEC
ENSG00000279799ENST00000623591SEC23AENSG00000100934ENST00000553970-0.13871-CHOL,BLCA,UCEC
ENSG00000279799ENST00000623591ABCA1ENSG00000165029ENST00000423487-0.103159-CHOL
ENSG00000279799ENST00000623591ABCA1ENSG00000165029ENST00000374733-0.13401-CHOL
ENSG00000279799ENST00000623591SMG6ENSG00000070366ENST00000536871-0.29624-UCEC
ENSG00000279799ENST00000623591YAP1ENSG00000137693ENST00000531439-0.763314-UCEC
ENSG00000279799ENST00000623591CORO1CENSG00000110880ENST00000546705-0.1219312-BLCA,UCEC
ENSG00000279799ENST00000623591CORO1CENSG00000110880ENST00000421578-0.61828-BLCA,UCEC
ENSG00000279799ENST00000623591PCDHGC3ENSG00000240184ENST00000611950-0.2117106-BLCA,UCEC
ENSG00000279799ENST00000623591PCDHGC3ENSG00000240184ENST00000617641-0.10241-BLCA,UCEC
ENSG00000279799ENST00000623591PCDHGC3ENSG00000240184ENST00000617222-0.2892316-BLCA,UCEC
ENSG00000279799ENST00000623591PCDHGC3ENSG00000240184ENST00000308177-0.10241-BLCA,UCEC
ENSG00000279799ENST00000623591SEC24DENSG00000150961ENST00000506622-0.11541-CHOL
ENSG00000279799ENST00000623591NPTNENSG00000156642ENST00000565325-0.10431-UCEC
ENSG00000279799ENST00000623591NPTNENSG00000156642ENST00000562924-0.10771-UCEC
ENSG00000279799ENST00000623591PDLIM5ENSG00000163110ENST00000509357-0.13561-CHOL,BLCA,UCEC
ENSG00000279799ENST00000623591PDLIM5ENSG00000163110ENST00000506632-0.115216-CHOL,BLCA,UCEC
ENSG00000279799ENST00000623591SEPTIN10ENSG00000186522ENST00000437928-0.1433110-BLCA,UCEC
ENSG00000279799ENST00000623591AFAP1ENSG00000196526ENST00000360265-0.10251-BLCA
ENSG00000279799ENST00000623591AFAP1ENSG00000196526ENST00000358461-0.10251-BLCA
ENSG00000279799ENST00000623591AFAP1ENSG00000196526ENST00000420658-0.10251-BLCA
ENSG00000279799ENST00000623591AFAP1ENSG00000196526ENST00000382543-0.21341-BLCA
ENSG00000279799ENST00000623591VCLENSG00000035403ENST00000624354-0.10641-BLCA,UCEC
ENSG00000279799ENST00000623591EDEM1ENSG00000134109ENST00000443790-0.139410-CHOL
ENSG00000279799ENST00000623591EDEM1ENSG00000134109ENST00000445686-0.28071-CHOL
ENSG00000279799ENST00000623591SEC24BENSG00000138802ENST00000399100-0.2420252-CHOL
ENSG00000279799ENST00000623591EAF1ENSG00000144597ENST00000449565-0.10431-CHOL
ENSG00000279799ENST00000623591ABHD5ENSG00000011198ENST00000413300-0.1939126-CHOL
ENSG00000279799ENST00000623591TRAM2ENSG00000065308ENST00000182527-0.10601-CHOL
ENSG00000279799ENST00000623591BCKDHBENSG00000083123ENST00000369760-0.2336299-CHOL
ENSG00000279799ENST00000623591HECTD1ENSG00000092148ENST00000554471-0.11511-CHOL
ENSG00000279799ENST00000623591TANGO6ENSG00000103047ENST00000261778-0.1330167-CHOL
ENSG00000279799ENST00000623591TANGO6ENSG00000103047ENST00000561856-0.101381-CHOL
ENSG00000279799ENST00000623591MPDZENSG00000107186ENST00000538841-0.10137-CHOL,BLCA,UCEC
ENSG00000279799ENST00000623591MPDZENSG00000107186ENST00000536827-0.17667-CHOL,BLCA,UCEC
ENSG00000279799ENST00000623591MPDZENSG00000107186ENST00000447879-0.19287-CHOL,BLCA,UCEC
ENSG00000279799ENST00000623591MPDZENSG00000107186ENST00000546205-0.9900168-CHOL,BLCA,UCEC
ENSG00000279799ENST00000623591MPDZENSG00000107186ENST00000494251-0.13961-CHOL,BLCA,UCEC
ENSG00000279799ENST00000623591HPS5ENSG00000110756ENST00000537258-0.13751-CHOL
ENSG00000279799ENST00000623591UHRF1BP1LENSG00000111647ENST00000548712-0.109239-CHOL
ENSG00000279799ENST00000623591LPCAT3ENSG00000111684ENST00000538910-0.11461-CHOL
ENSG00000279799ENST00000623591MRPL19ENSG00000115364ENST00000358788-0.113512-CHOL
ENSG00000279799ENST00000623591MRPL19ENSG00000115364ENST00000409374-0.13491-CHOL
ENSG00000279799ENST00000623591GGCXENSG00000115486ENST00000430215-0.172586-CHOL
ENSG00000279799ENST00000623591GGCXENSG00000115486ENST00000421496-0.13451-CHOL
ENSG00000279799ENST00000623591GGCXENSG00000115486ENST00000428479-0.10461-CHOL
ENSG00000279799ENST00000623591IL1R1ENSG00000115594ENST00000409329-0.1102239-CHOL
ENSG00000279799ENST00000623591IL1R1ENSG00000115594ENST00000409288-0.2003109-CHOL
ENSG00000279799ENST00000623591IL1R1ENSG00000115594ENST00000422532-0.136529-CHOL
ENSG00000279799ENST00000623591ACADMENSG00000117054ENST00000420607-0.1589276-CHOL
ENSG00000279799ENST00000623591ACADMENSG00000117054ENST00000528016-0.18021-CHOL
ENSG00000279799ENST00000623591RDXENSG00000137710ENST00000405097-0.11261-CHOL
ENSG00000279799ENST00000623591RDXENSG00000137710ENST00000528900-0.11261-CHOL
ENSG00000279799ENST00000623591RDXENSG00000137710ENST00000530301-0.11261-CHOL
ENSG00000279799ENST00000623591RDXENSG00000137710ENST00000534683-0.1623346-CHOL
ENSG00000279799ENST00000623591RDXENSG00000137710ENST00000533678-0.124156-CHOL
ENSG00000279799ENST00000623591GOLGA4ENSG00000144674ENST00000361924-0.13191-CHOL
ENSG00000279799ENST00000623591GOLGA4ENSG00000144674ENST00000444882-0.16281-CHOL
ENSG00000279799ENST00000623591GOLGA4ENSG00000144674ENST00000356847-0.16281-CHOL
ENSG00000279799ENST00000623591GOLGA4ENSG00000144674ENST00000437131-0.16281-CHOL
ENSG00000279799ENST00000623591SLC25A25ENSG00000148339ENST00000373068-0.11141-CHOL,BLCA,UCEC
ENSG00000279799ENST00000623591SLC25A25ENSG00000148339ENST00000373069-0.11141-CHOL,BLCA,UCEC
ENSG00000279799ENST00000623591SLC25A25ENSG00000148339ENST00000373066-0.11141-CHOL,BLCA,UCEC
ENSG00000279799ENST00000623591SLC25A25ENSG00000148339ENST00000432073-0.11141-CHOL,BLCA,UCEC
ENSG00000279799ENST00000623591SLC25A25ENSG00000148339ENST00000373064-0.11141-CHOL,BLCA,UCEC
ENSG00000279799ENST00000623591ACOX1ENSG00000161533ENST00000588968-0.10121-CHOL
ENSG00000279799ENST00000623591ACOX1ENSG00000161533ENST00000572047-0.11911-CHOL
ENSG00000279799ENST00000623591ACOX1ENSG00000161533ENST00000589301-0.11181-CHOL
ENSG00000279799ENST00000623591RNF123ENSG00000164068ENST00000327697-0.14461-CHOL
ENSG00000279799ENST00000623591RNF123ENSG00000164068ENST00000432042-0.184965-CHOL
ENSG00000279799ENST00000623591RNF123ENSG00000164068ENST00000457726-0.11911-CHOL
ENSG00000279799ENST00000623591RNF123ENSG00000164068ENST00000443204-0.175210-CHOL
ENSG00000279799ENST00000623591RNF123ENSG00000164068ENST00000433785-0.13161-CHOL
ENSG00000279799ENST00000623591RNF123ENSG00000164068ENST00000444689-0.113037-CHOL

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000279799.1ENST00000623591.154363199