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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000273568

Summary for RP11-417L19.6

check button Gene summary

Gene informationEnsembl ID

ENSG00000273568

Gene symbol

RP11-417L19.6

Gene name
HGNC
Entrez ID
Gene typesense_intronic
Synonyms
UniProtAcc

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Structure and expression level for RP11-417L19.6

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002735681.901173e+011.358950e+001.251739e-011.085649e+011.860000e-271.670000e-26UPKIRC
ENSG000002735683.062434e+011.493286e+002.453136e-016.087251e+001.150000e-091.960000e-08UPBLCA
ENSG000002735682.672843e+012.369057e+006.534700e-013.625349e+002.885710e-042.912182e-03UPCESC
ENSG000002735682.216600e+011.239694e+001.880148e-016.593596e+004.290000e-113.530000e-10UPHNSC
ENSG000002735681.630985e+011.058184e+001.842415e-015.743462e+009.280000e-095.600000e-08UPKIRP
ENSG000002735681.575516e+011.683347e+001.904017e-018.841029e+009.480000e-191.390000e-17UPUCEC
ENSG000002735682.110807e+011.422584e+001.409039e-011.009613e+015.750000e-242.480000e-22UPPRAD
ENSG000002735682.918714e+011.345992e+001.337690e-011.006206e+018.130000e-246.460000e-23UPLUSC
ENSG000002735681.967111e+011.303938e+001.435598e-019.082892e+001.060000e-191.040000e-18UPLUAD
ENSG000002735683.256911e+011.530745e+001.516804e-011.009191e+016.000000e-241.060000e-22UPCOAD
ENSG000002735683.350544e+011.839663e+001.917329e-019.594927e+008.400000e-227.540000e-20UPSTAD
ENSG000002735683.611371e+011.859714e+003.465342e-015.366610e+008.020000e-081.330000e-06UPREAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002735684.093179e-015.238443e-03CHOL6.767328e-03
ENSG000002735683.279717e-011.031805e-16KIRC5.367772e-16
ENSG000002735683.867387e-014.230591e-21PRAD1.186983e-19
ENSG000002735683.039923e-015.138994e-14UCEC3.791879e-13

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lncRNA-Protein interaction for RP11-417L19.6

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000273568ENST00000621809RP11-417L19.6ENSG00000183495EP40010.4491.1553Q96L91EpiNA
ENSG00000273568ENST00000621809RP11-417L19.6ENSG00000118058KMT2A17.8892.4368Q03164TF,EpiNA
ENSG00000273568ENST00000621809RP11-417L19.6ENSG00000171316CHD713.790.7478Q9P2D1EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000273568ENST00000621809RP11-417L19.6ENSG00000118058KMT2A17.8892.087Q03164TF,EpiNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for RP11-417L19.6

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-417L19.6

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
CPQ,SH3GLB1,TOR1AIP1,SMPD1,SOS2,PRKACA,ILK,TMEM127,SDHD,SEC31A,APP,SNX6,SCP2,LRP10,YIPF5,PDK2,RALB,BTD,ANXA5,LMBRD1,WBP1L,KIAA1191,OS9,SEC24B,PLSCR4,FTO
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000273568ENST00000621809exon_skip_114200chr14:73279280-73279424-17.12-0.2038NUMBENST00000355058,ENST00000555238In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000273568ENST00000621809exon_skip_353131chr20:58669290-58669453-16.30-0.1148STX16ENST00000371141Frame-shift
ENSG00000273568ENST00000621809exon_skip_52891chr10:98429790-98429889-17.58-0.2225HPS1ENST00000325103,ENST00000361490In-frame
ENSG00000273568ENST00000621809exon_skip_140283chr16:635611-635774-21.21-0.1405METTL26ENST00000301686Frame-shift
ENSG00000273568ENST00000621809exon_skip_140339chr16:635611-635774-21.21-0.1405METTL26ENST00000301686Frame-shift
ENSG00000273568ENST00000621809exon_skip_305660chr19:35269802-35270003-25.56-0.1852USF2ENST00000222305In-frame
ENSG00000273568ENST00000621809exon_skip_322579chr19:55455635-55455845-25.98-0.1353ISOC2ENST00000425675In-frame
ENSG00000273568ENST00000621809exon_skip_380242chr3:186784961-186785101-11.53-0.1441EIF4A2ENST00000323963Frame-shift
ENSG00000273568ENST00000621809exon_skip_382458chr3:38131595-38131638-8.06-0.2239ACAA1ENST00000333167Frame-shift
ENSG00000273568ENST00000621809exon_skip_132563chr16:2527560-2527615-9.15-0.2691AMDHD2ENST00000293971Frame-shift
ENSG00000273568ENST00000621809exon_skip_370518chr22:50247691-50247776-15.11-0.1988HDAC10ENST00000216271Frame-shift
ENSG00000273568ENST00000621809exon_skip_60654chr11:64288064-64288214-17.42-0.1281GPR137ENST00000313074In-frame
ENSG00000273568ENST00000621809exon_skip_382439chr3:38126161-38126341-15.81-0.1630ACAA1ENST00000333167In-frame
ENSG00000273568ENST00000621809exon_skip_124988chr15:90890981-90891191-22.14-0.1326FESENST00000328850In-frame

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for RP11-417L19.6

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000273568ENST00000621809PLSCR4ENSG00000114698ENST00000493382-0.1648170-BLCA,UCEC,LUSC,LUAD,COAD,READ
ENSG00000273568ENST00000621809SCP2ENSG00000116171ENST00000478631-0.10661-COAD,READ
ENSG00000273568ENST00000621809SCP2ENSG00000116171ENST00000528311-0.13821-COAD,READ
ENSG00000273568ENST00000621809BTDENSG00000169814ENST00000417015-0.10791-CESC,LUSC,COAD,STAD
ENSG00000273568ENST00000621809BTDENSG00000169814ENST00000449107-0.168165-CESC,LUSC,COAD,STAD
ENSG00000273568ENST00000621809SDHDENSG00000204370ENST00000528182-0.10331-COAD,READ
ENSG00000273568ENST00000621809SDHDENSG00000204370ENST00000528048-0.10331-COAD,READ
ENSG00000273568ENST00000621809SDHDENSG00000204370ENST00000526592-0.12231-COAD,READ
ENSG00000273568ENST00000621809SDHDENSG00000204370ENST00000534010-0.106241-COAD,READ
ENSG00000273568ENST00000621809CPQENSG00000104324ENST00000522617-0.135141-BLCA,CESC,UCEC,LUSC,COAD,READ
ENSG00000273568ENST00000621809ILKENSG00000166333ENST00000532063-0.10741-BLCA,CESC,UCEC,PRAD,LUSC,COAD,STAD,READ
ENSG00000273568ENST00000621809ILKENSG00000166333ENST00000299421-0.10741-BLCA,CESC,UCEC,PRAD,LUSC,COAD,STAD,READ
ENSG00000273568ENST00000621809ILKENSG00000166333ENST00000537806-0.10741-BLCA,CESC,UCEC,PRAD,LUSC,COAD,STAD,READ
ENSG00000273568ENST00000621809ILKENSG00000166333ENST00000420936-0.10741-BLCA,CESC,UCEC,PRAD,LUSC,COAD,STAD,READ
ENSG00000273568ENST00000621809ILKENSG00000166333ENST00000528995-0.10741-BLCA,CESC,UCEC,PRAD,LUSC,COAD,STAD,READ
ENSG00000273568ENST00000621809ILKENSG00000166333ENST00000396751-0.10741-BLCA,CESC,UCEC,PRAD,LUSC,COAD,STAD,READ
ENSG00000273568ENST00000621809ILKENSG00000166333ENST00000526318-0.10741-BLCA,CESC,UCEC,PRAD,LUSC,COAD,STAD,READ
ENSG00000273568ENST00000621809KIAA1191ENSG00000122203ENST00000298569-0.10161-KIRP
ENSG00000273568ENST00000621809KIAA1191ENSG00000122203ENST00000393725-0.10161-KIRP
ENSG00000273568ENST00000621809KIAA1191ENSG00000122203ENST00000614420-0.10161-KIRP
ENSG00000273568ENST00000621809KIAA1191ENSG00000122203ENST00000620366-0.10161-KIRP
ENSG00000273568ENST00000621809KIAA1191ENSG00000122203ENST00000510164-0.116274-KIRP
ENSG00000273568ENST00000621809KIAA1191ENSG00000122203ENST00000533553-0.1501117-KIRP
ENSG00000273568ENST00000621809ANXA5ENSG00000164111ENST00000513728-0.104774-LUSC
ENSG00000273568ENST00000621809SOS2ENSG00000100485ENST00000543680-0.4247112-COAD,READ
ENSG00000273568ENST00000621809SOS2ENSG00000100485ENST00000556452-0.131472-COAD,READ

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000273568.1ENST00000621809.111774424