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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000273230

Summary for RP11-1246C19.1

check button Gene summary

Gene informationEnsembl ID

ENSG00000273230

Gene symbol

RP11-1246C19.1

Gene name
HGNC
Entrez ID
Gene typelincRNA
Synonyms
UniProtAcc

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Structure and expression level for RP11-1246C19.1

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002732301.459174e+022.614341e+002.980904e-018.770295e+001.780000e-187.020000e-17UPCHOL
ENSG000002732302.427846e+021.408809e+002.246695e-016.270585e+003.600000e-102.100000e-09UPKICH
ENSG000002732302.683178e+022.218181e+004.027462e-015.507640e+003.640000e-081.860000e-06UPPCPG
ENSG000002732301.558071e+021.092783e+001.718676e-016.358287e+002.040000e-109.720000e-10UPLUAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002732305.186505e-011.351549e-06ACC3.243718e-04
ENSG000002732304.606640e-011.450546e-03CHOL2.314818e-03
ENSG000002732304.840164e-011.543815e-06KICH4.161588e-06

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lncRNA-Protein interaction for RP11-1246C19.1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000118058KMT2A70.9497.1636Q03164TF,EpiNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000110851PRDM468.290.2192Q9UKN5TF,EpiNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000141644MBD129.4992.4738Q9UIS9TF,EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000164916FOXK172.5792.8178P85037TFNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000167967E4F172.393.5569Q66K89TFNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000118058KMT2A70.9497.1899Q03164TF,EpiNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000110851PRDM468.290.3926Q9UKN5TF,EpiNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000105127AKAP864.9993.9861O43823TFNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000146587RBAK61.291.963Q9NYW8TFNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000099326MZF159.2491.4831P28698TFNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000125482TTF157.8392.9143Q15361TFNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000198815FOXJ352.3592.9206Q9UPW0TFNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000164631ZNF1246.3290.6473P17014TFNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000196670ZFP6245.1691.4448Q8NB50TFNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000198040ZNF8437.7991.542P51523TFNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000166526ZNF331.4492.5395P17036TFNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000141644MBD129.4992.6207Q9UIS9TF,EpiNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000197951ZNF7126.3691.7015Q9NQZ8TFNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000196152ZNF7915.2191.8512Q15937TFNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000146757ZNF9213.7292.0901Q03936TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000075856SART372.6291.5552Q15020RBPNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000137776SLTM63.9794.5294Q9NWH9RBPNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000198000NOL863.5994.3799Q76FK4RBPNA
ENSG00000273230ENST00000609755RP11-1246C19.1ENSG00000135870RC3H144.7191.9854Q5TC82RBPNA

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lncRNA-DNA interaction for RP11-1246C19.1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
CNOT4,RBM19,PRR12,AQR,MECP2,FOXJ3,RBM6,NOP2,ILF3,RBM48,GLI4,SCAF4,NOL6,EDC3,TTF1,GMEB2,SART3,XPO1,RBM5,RC3H1,DDX56,TIGD5,ZFP62,MZF1,SGSM2,NRF1,AKAP8,SRCAP,ZXDC,ZNF84,SUGP2,CELF1,SCMH1,DMTF1,REXO4,RBM14,DDX51,TRA2A,PURB,ADNP,NCBP1,MYEF2,MBD1,KMT2A,DHX34,RBM28,HINFP,DDX31,CPSF4,EIF3B,DDX55,KMT2B,CPSF7,ZMAT1,PRDM4,ZBTB6,ZNF3,ZNF71,SAFB2,NOP9,RBM33,DDX17,NOL8,NR2C2,SIX5
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.
Only predicted by TDF
CNOT4,TTF1,KMT2B,NRF1,MZF1,E4F1,GTF2I,MECP2,ZFP62,ZMAT1,SIX5,DDX31,SCMH1,ZNF3,CPSF7,FOXK1,RC3H1,KDM2A,ADNP,RBM6,NFX1,ZNF71,DHX34,CPSF4,KMT2A,ZBTB6,ZXDC
Exist in public source
NA

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-1246C19.1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000273230ENST00000609755exon_skip_325891chr2:62987930-62988038-12.41-0.1748EHBP1ENST00000263991In-frame

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for RP11-1246C19.1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types
ENSG00000273230ENSG00000146587RBAKENSG00000080802CNOT46CHOL,GBM,KIRP,MESO,PCPG,THYM
ENSG00000273230ENSG00000164631ZNF12ENSG00000080802CNOT46CHOL,GBM,KIRP,MESO,TGCT,THYM
ENSG00000273230ENSG00000164916FOXK1ENSG00000272333KMT2B5ACC,GBM,KICH,LUAD,MESO
ENSG00000273230ENSG00000146587RBAKENSG00000106459NRF16ACC,CHOL,GBM,KIRP,LGG,PCPG
ENSG00000273230ENSG00000164631ZNF12ENSG00000106459NRF17ACC,CHOL,GBM,KIRP,LAML,SARC,TGCT
ENSG00000273230ENSG00000164916FOXK1ENSG00000106459NRF16ACC,CHOL,GBM,KIRP,LGG,SARC
ENSG00000273230ENSG00000166526ZNF3ENSG00000106459NRF16ACC,CHOL,KIRP,LAML,LGG,PCPG
ENSG00000273230ENSG00000196670ZFP62ENSG00000106459NRF15ACC,CHOL,GBM,PCPG,TGCT
ENSG00000273230ENSG00000167967E4F1ENSG00000099326MZF15CHOL,GBM,KIRP,LAML,LGG
ENSG00000273230ENSG00000099326MZF1ENSG00000167967E4F15CHOL,GBM,KIRP,LAML,LGG
ENSG00000273230ENSG00000164631ZNF12ENSG00000263001GTF2I5CHOL,GBM,LAML,MESO,TGCT
ENSG00000273230ENSG00000146587RBAKENSG00000196670ZFP625ACC,CHOL,GBM,PCPG,THYM
ENSG00000273230ENSG00000164631ZNF12ENSG00000196670ZFP625ACC,CHOL,GBM,TGCT,THYM
ENSG00000273230ENSG00000146587RBAKENSG00000166432ZMAT15GBM,KIRP,MESO,PCPG,THYM
ENSG00000273230ENSG00000164631ZNF12ENSG00000166432ZMAT15KIRP,LAML,MESO,SARC,THYM
ENSG00000273230ENSG00000146587RBAKENSG00000125485DDX315ACC,CHOL,GBM,PCPG,THYM
ENSG00000273230ENSG00000146587RBAKENSG00000166526ZNF36ACC,CHOL,KIRP,LGG,MESO,PCPG
ENSG00000273230ENSG00000146757ZNF92ENSG00000166526ZNF35ACC,CHOL,KIRP,MESO,TGCT
ENSG00000273230ENSG00000164631ZNF12ENSG00000166526ZNF36ACC,CHOL,KIRP,LAML,MESO,SKCM
ENSG00000273230ENSG00000164916FOXK1ENSG00000166526ZNF36ACC,CHOL,KICH,KIRP,LGG,MESO
ENSG00000273230ENSG00000198040ZNF84ENSG00000166526ZNF35CHOL,KIRP,LAML,MESO,PCPG
ENSG00000273230ENSG00000146587RBAKENSG00000149532CPSF76CHOL,GBM,LGG,MESO,PCPG,THYM
ENSG00000273230ENSG00000146587RBAKENSG00000164916FOXK16ACC,CHOL,GBM,KIRP,LGG,MESO
ENSG00000273230ENSG00000164631ZNF12ENSG00000164916FOXK16ACC,CHOL,KIRP,MESO,SARC,SKCM
ENSG00000273230ENSG00000166526ZNF3ENSG00000164916FOXK16ACC,CHOL,KICH,KIRP,LGG,MESO
ENSG00000273230ENSG00000146587RBAKENSG00000086102NFX15ACC,CHOL,GBM,PCPG,THYM

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000273230.1ENST00000609755.1922750