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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000272927

Summary for RP11-1191J2.5

check button Gene summary

Gene informationEnsembl ID

ENSG00000272927

Gene symbol

RP11-1191J2.5

Gene name
HGNC
Entrez ID
Gene typeantisense
Synonyms
UniProtAcc

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Structure and expression level for RP11-1191J2.5

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002729272.889422e+013.248595e+007.703741e-014.216906e+002.480000e-051.236900e-04UPCHOL
ENSG000002729271.865414e+022.221415e+002.632239e-018.439258e+003.190000e-175.770000e-16UPKIRP
ENSG000002729272.413921e+01-1.060713e+003.373865e-01-3.143911e+001.667061e-034.093804e-03DOWNUCEC
ENSG000002729274.412080e+013.374933e+008.625654e-013.912670e+009.130000e-051.682528e-03UPPCPG

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002729273.482042e-011.907942e-02CHOL2.086579e-02
ENSG00000272927-3.717814e-013.341394e-04KICH5.155407e-04

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lncRNA-Protein interaction for RP11-1191J2.5

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000272927ENST00000609172RP11-1191J2.5ENSG00000001497LAS1L52.9890.4Q9Y4W2EpiNA
ENSG00000272927ENST00000609172RP11-1191J2.5ENSG00000132600PRMT735.4590.5939Q9NVM4EpiNA
ENSG00000272927ENST00000609172RP11-1191J2.5ENSG00000162227TAF6L10.5890.6822Q9Y6J9EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000272927ENST00000609172RP11-1191J2.5ENSG00000141258SGSM247.592.8616O43147TFNA
ENSG00000272927ENST00000609172RP11-1191J2.5ENSG00000256223ZNF1012.9790.3198P21506TFNA
ENSG00000272927ENST00000609172RP11-1191J2.5ENSG00000120798NR2C18.8190.5643P13056TFNA
ENSG00000272927ENST00000609172RP11-1191J2.5ENSG00000102878HSF46.3392.9286Q9ULV5TFNA
ENSG00000272927ENST00000609172RP11-1191J2.5ENSG00000221944TIGD15.491.9652Q96MW7TFNA
ENSG00000272927ENST00000609172RP11-1191J2.5ENSG00000126456IRF32.890.5853Q14653TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000272927ENST00000609172RP11-1191J2.5ENSG00000013573DDX1170.1394.5953Q96FC9RBPNA

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lncRNA-DNA interaction for RP11-1191J2.5

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-1191J2.5

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
CNOT1,IDH3A,L2HGDH,GGCX,ATP2A2,SNX2,SEC23B,AGFG1,EIF3L,GNS,ACLY,EIF4G2,RAB31,HSPA8,M6PR,USP9X,HSPA9,ARSB,MYH9,UHRF1BP1L,SNX12,ACVR1,CDH5,HUWE1,CCT5,HSPA4,EPRS1,SSR3,YME1L1,ACO2,UGGT1,USP32,LSM12,ACTR3,ABCE1,DYNC1I2,ITGAV,MCMBP,DOCK7,SF3A1,EIF4G1,SEC23A,TMLHE,PRMT5,DDB1,VPS26A,NCOA2,ABHD5,CSTF2,PSMD1,RAB6A,PSMC1,ACTR2,RPN2,CAP1,PTDSS1,CLTC,TARS1
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000272927ENST00000609172exon_skip_41813chr10:68337857-68337996-24.10-0.1975HNRNPH3ENST00000265866Frame-shift
ENSG00000272927ENST00000609172exon_skip_87733chr12:120571190-120571291-14.35-0.1772RNF10ENST00000325954Frame-shift
ENSG00000272927ENST00000609172exon_skip_114365chr14:74290026-74290118-15.34-0.1942ABCD4ENST00000356924Frame-shift
ENSG00000272927ENST00000609172exon_skip_152672chr17:42540949-42541206-24.26-0.1011NAGLUENST00000225927Frame-shift
ENSG00000272927ENST00000609172exon_skip_319223chr19:43526200-43526349-19.81-0.1693ETHE1ENST00000292147Frame-shift
ENSG00000272927ENST00000609172exon_skip_374375chr3:49675182-49675309-16.72-0.1990APEHENST00000296456Frame-shift
ENSG00000272927ENST00000609172exon_skip_382458chr3:38131595-38131638-9.32-4.6600ACAA1ENST00000333167Frame-shift
ENSG00000272927ENST00000609172exon_skip_431827chr4:109696409-109696486-7.68-0.1371CASP6ENST00000265164Frame-shift
ENSG00000272927ENST00000609172exon_skip_433210chr4:177436275-177436351-12.89-0.1953AGAENST00000264595Frame-shift
ENSG00000272927ENST00000609172exon_skip_442657chr5:74730259-74730398-14.71-0.1236GFM2ENST00000296805,ENST00000509430Frame-shift
ENSG00000272927ENST00000609172exon_skip_470226chr7:103307595-103307708-14.12-0.1345PMPCBENST00000249269Frame-shift
ENSG00000272927ENST00000609172exon_skip_339830chr2:69423581-69423717-14.12-0.2107NFU1ENST00000410022Frame-shift

check buttonlncRNA targets by miRNA.
lncRNA targets by miRNA
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source
ENSG00000272927hsa-mir-224ENST00000609172chr4:661618-661698189.00-76.5378NA
ENSG00000272927hsa-mir-224ENST00000609172chr4:661329-661405157.00-63.1075NA
ENSG00000272927hsa-mir-224ENST00000609172chr4:661854-661946151.00-54.1480NA
ENSG00000272927hsa-mir-224ENST00000609172chr4:661487-661573150.00-61.1684NA
ENSG00000272927hsa-mir-224ENST00000609172chr4:661210-661265148.00-67.2155NA
ENSG00000272927hsa-mir-452ENST00000609172chr4:661484-661576171.00-62.8885NA
ENSG00000272927hsa-mir-452ENST00000609172chr4:661761-661849161.00-76.5373NA
ENSG00000272927hsa-mir-452ENST00000609172chr4:661305-661395145.00-72.4267NA
ENSG00000272927hsa-mir-22ENST00000609172chr4:661326-661403172.00-72.2986NA
ENSG00000272927hsa-mir-22ENST00000609172chr4:661766-661860168.00-87.2293NA
ENSG00000272927hsa-mir-22ENST00000609172chr4:661543-661624162.00-61.6276NA
ENSG00000272927hsa-mir-22ENST00000609172chr4:661210-661288160.00-90.0381NA
ENSG00000272927hsa-mir-22ENST00000609172chr4:661423-661512158.00-99.5891NA
ENSG00000272927hsa-mir-22ENST00000609172chr4:661644-661731150.00-81.4988NA

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Variants for RP11-1191J2.5

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000272927ENST00000609172ACTR3ENSG00000115091ENST00000535589-0.1011457-PCPG
ENSG00000272927ENST00000609172L2HGDHENSG00000087299ENST00000261699-0.2022552-CHOL,KIRP
ENSG00000272927ENST00000609172L2HGDHENSG00000087299ENST00000555423-0.1263655-CHOL,KIRP
ENSG00000272927ENST00000609172L2HGDHENSG00000087299ENST00000555610-0.16821-CHOL,KIRP
ENSG00000272927ENST00000609172SEC23AENSG00000100934ENST00000548032-0.11211-CHOL
ENSG00000272927ENST00000609172SEC23AENSG00000100934ENST00000557280-0.1339425-CHOL
ENSG00000272927ENST00000609172SEC23AENSG00000100934ENST00000553970-0.1339425-CHOL
ENSG00000272927ENST00000609172GGCXENSG00000115486ENST00000430215-0.1029125-CHOL
ENSG00000272927ENST00000609172GGCXENSG00000115486ENST00000428479-0.100617-CHOL
ENSG00000272927ENST00000609172TMLHEENSG00000185973ENST00000369439-0.5517248-CHOL
ENSG00000272927ENST00000609172SSR3ENSG00000114850ENST00000463503-0.417449-PCPG
ENSG00000272927ENST00000609172SSR3ENSG00000114850ENST00000496050-0.5215183-PCPG
ENSG00000272927ENST00000609172EIF4G1ENSG00000114867ENST00000346169-0.105739-PCPG
ENSG00000272927ENST00000609172EIF4G1ENSG00000114867ENST00000414031-0.105739-PCPG
ENSG00000272927ENST00000609172EIF4G1ENSG00000114867ENST00000392537-0.105741-PCPG
ENSG00000272927ENST00000609172EIF4G1ENSG00000114867ENST00000382330-0.2420140-PCPG
ENSG00000272927ENST00000609172EIF4G1ENSG00000114867ENST00000350481-0.105739-PCPG
ENSG00000272927ENST00000609172EIF4G1ENSG00000114867ENST00000342981-0.100734-PCPG
ENSG00000272927ENST00000609172EIF4G1ENSG00000114867ENST00000424196-0.105741-PCPG
ENSG00000272927ENST00000609172EIF4G1ENSG00000114867ENST00000434061-0.105741-PCPG
ENSG00000272927ENST00000609172EIF4G1ENSG00000114867ENST00000319274-0.105741-PCPG
ENSG00000272927ENST00000609172EIF4G1ENSG00000114867ENST00000435046-0.105745-PCPG
ENSG00000272927ENST00000609172EIF4G1ENSG00000114867ENST00000422614-0.11661-PCPG
ENSG00000272927ENST00000609172GNSENSG00000135677ENST00000542058-0.1008394-PCPG
ENSG00000272927ENST00000609172CDH5ENSG00000179776ENST00000539168-0.142294-KIRP
ENSG00000272927ENST00000609172RAB31ENSG00000168461ENST00000581109-0.77891-PCPG

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000272927.1ENST00000609172.1161108593