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lncRNA: ENSG00000272841

Summary for MAP3K4-AS1

Gene summary

Gene information	Ensembl ID	ENSG00000272841
	Gene symbol	MAP3K4-AS1
	Gene name	MAP3K4 antisense RNA 1
	HGNC	55048
	Entrez ID
	Gene type	antisense
	Synonyms	06q26\|RP3-428L16.2\|MAP3K4-AS1
	UniProtAcc

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Structure and expression level for MAP3K4-AS1

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000272841	7.977631e+01	-1.341905e+00	2.023767e-01	-6.630727e+00	3.340000e-11	2.400000e-10	DOWN	UCEC
ENSG00000272841	3.340363e+02	1.313032e+00	1.044441e-01	1.257162e+01	3.020000e-36	3.940000e-35	UP	BRCA

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID

Correlation

P-value

Cancer Type

Adjc.p-value

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lncRNA-Protein interaction for MAP3K4-AS1

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

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lncRNA-DNA interaction for MAP3K4-AS1

lncRNA targets the enhancer region and positively regulates the gene expression.

Only predicted by TDF

FN1,GOPC,TMEM119,ANGPTL2,PXDN,DENND5A,PPP1R18,NID2,MEIS3,VSTM4,WNT2,COL6A2,FNDC1,IGFBP7,ADAMTS12,GFPT2,FBN1,COL5A2,GXYLT2,C1QTNF6,CDH11,TWSG1,PDGFRB,FKBP7,PMP22,OLFML1,P3H3,GLI3,PHLDB1,LHFPL6,INHBA,CILP,ROR2,RUNX1,SNAI2,COL6A3,ATP8B2,GPC6,RNF144A,FAM171B,FHL3,MXRA5,ANKH,HEYL,MAP3K4,SPARC,PTK7,SERINC1,DCHS1,PCDH18,BTBD19,CCN2,NUAK1,TSPAN9,TIMP2,SPON2,ARSI,POGLUT2,CTSK,LRRC15,FKBP10,CHST14,HTRA1,POSTN,CNRIP1,IGFBP4,CLEC14A,NREP,EFEMP2,COL5A3,CNN3,LRP1,MXRA8,LIX1L,SYT11,DIPK2B,CD34,SCARF2,MMP19,GREM1,RARA,ADAMTS2,BGN,MAFB,CD248,S1PR2,BACE1,ITGB5,NID1,PLXDC1,ACVR1,EVC,PODNL1,RCN3,MMP14,UBTD2,MAP4K5,LAMB1,ADGRA2,SULF2,COL14A1,HLX,CCN1,MFAP2,SFRP2,SRPX2,LOXL1,COL18A1,EID1,CLEC11A,GASK1B,HEG1,COPZ2,ADAM12,TMEM200A,COL12A1,LOX,COL16A1,LRRC32,OLFML3,RTL8B,LRP12,LAMA4,F2R,GAS1,IKBIP,THBS2,POGLUT3,GINM1,COL10A1,BMP1,ARSB,GAS7,FYN,PCOLCE,RASSF8,CSGALNACT2,QKI,DPYSL3,MYH10,MFGE8,CYBRD1,MRC2,UBTD1,LUM,FSTL1,GEM,PCDH12,HIC1,FAP,SEPTIN7,CPXM1,RBMS1,TRIL,COL1A1,DSE,SFRP4,COLEC12,ARL4C,CHSY1,GLT8D2,ITPRIP,COPS8,COL8A2,GPX8,P3H1,ADGRL4,TGFB3,LGALS1,MAF,OLFML2B,SH3PXD2A,FAM20C,TGFB1

Exist in public source

lncRNA targets the promoter region and positively regulates the gene expression.

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for MAP3K4-AS1

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

lncRNA and exonskipping events positive correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	ORF mutation
ENSG00000272841	ENST00000608721	exon_skip_96112	chr12:109945259-109945349	-17.85	-0.2125	GIT2	ENST00000355312	In-frame
ENSG00000272841	ENST00000608721	exon_skip_508298	chr9:136445051-136445111	-9.98	-0.2772	SEC16A	ENST00000313050	In-frame
ENSG00000272841	ENST00000608721	exon_skip_21610	chr1:9737497-9737554	-11.06	-0.2514	CLSTN1	ENST00000377298	In-frame
ENSG00000272841	ENST00000608721	exon_skip_287874	chr17:29085603-29085648	-6.22	-0.2221	MYO18A	ENST00000527372	In-frame

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000272841	ENST00000608721	exon_skip_44853	chr10:104010815-104010908	-12.83	-0.2069	SLK	ENST00000369755	In-frame
ENSG00000272841	ENST00000608721	exon_skip_44998	chr10:110132304-110132400	-10.78	-0.1135	ADD3	ENST00000356080	In-frame
ENSG00000272841	ENST00000608721	exon_skip_435063	chr5:66075023-66075230	-26.91	-0.1313	ERBIN	ENST00000284037	In-frame

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for MAP3K4-AS1

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID	PC Gene ID	PC Gene Name	Positive correlated cancers	Cancer with PC gene up-regulation	Cancer with PC gene down-regulation
ENSG00000272841	ENSG00000020181	ADGRA2	ACC,BLCA,HNSC,PAAD,STAD,TGCT,THYM,UCEC		UCEC
ENSG00000272841	ENSG00000035862	TIMP2	ACC,BLCA,BRCA,CESC,ESCA,HNSC,PAAD,STAD,TGCT,UCEC,UCS		UCEC
ENSG00000272841	ENSG00000071967	CYBRD1	ACC,BLCA,PAAD,TGCT,THYM,UCEC		UCEC
ENSG00000272841	ENSG00000079150	FKBP7	ACC,BLCA,BRCA,HNSC,PAAD,STAD,TGCT,THYM,UCEC		UCEC
ENSG00000272841	ENSG00000101825	MXRA5	ACC,BLCA,BRCA,HNSC,PAAD,TGCT	BRCA
ENSG00000272841	ENSG00000107957	SH3PXD2A	ACC,BRCA,PAAD,STAD,THYM,UCEC		UCEC
ENSG00000272841	ENSG00000108821	COL1A1	ACC,BLCA,BRCA,ESCA,HNSC,PAAD,STAD,TGCT	BRCA
ENSG00000272841	ENSG00000113721	PDGFRB	ACC,BLCA,BRCA,ESCA,HNSC,PAAD,STAD,TGCT,UCEC		UCEC
ENSG00000272841	ENSG00000115414	FN1	ACC,BRCA,HNSC,PAAD,STAD,TGCT,THYM	BRCA
ENSG00000272841	ENSG00000116962	NID1	ACC,BRCA,CESC,HNSC,PAAD,TGCT,UCEC		UCEC
ENSG00000272841	ENSG00000117122	MFAP2	ACC,BRCA,CESC,ESCA,HNSC,PAAD,STAD,TGCT,THCA	BRCA
ENSG00000272841	ENSG00000119865	CNRIP1	ACC,PAAD,TGCT,THYM,UCEC		UCEC
ENSG00000272841	ENSG00000120820	GLT8D2	ACC,BLCA,BRCA,ESCA,HNSC,PAAD,STAD,TGCT,UCEC		UCEC
ENSG00000272841	ENSG00000122545	SEPTIN7	ACC,PAAD,TGCT,THYM,UCEC		UCEC
ENSG00000272841	ENSG00000129038	LOXL1	ACC,BRCA,CESC,ESCA,PAAD,STAD,TGCT	BRCA
ENSG00000272841	ENSG00000133110	POSTN	ACC,BLCA,BRCA,CESC,ESCA,HNSC,PAAD,SARC,STAD,TGCT,UCS	BRCA
ENSG00000272841	ENSG00000133466	C1QTNF6	ACC,BRCA,HNSC,PAAD,STAD	BRCA
ENSG00000272841	ENSG00000139329	LUM	ACC,BLCA,BRCA,ESCA,HNSC,PAAD,STAD,TGCT,UCEC		UCEC
ENSG00000272841	ENSG00000143387	CTSK	ACC,ESCA,PAAD,STAD,UCEC		UCEC
ENSG00000272841	ENSG00000148841	ITPRIP	ACC,BLCA,ESCA,PAAD,UCEC		UCEC
ENSG00000272841	ENSG00000157227	MMP14	ACC,BLCA,BRCA,CESC,ESCA,HNSC,PAAD,STAD,TGCT,UCEC,UCS	BRCA
ENSG00000272841	ENSG00000161381	PLXDC1	ACC,BRCA,HNSC,PAAD,STAD,TGCT,THCA,UCEC		UCEC
ENSG00000272841	ENSG00000162745	OLFML2B	ACC,BLCA,BRCA,ESCA,HNSC,PAAD,STAD,TGCT,UCEC	BRCA
ENSG00000272841	ENSG00000163359	COL6A3	ACC,BLCA,BRCA,ESCA,HNSC,PAAD,STAD,TGCT,UCEC		UCEC
ENSG00000272841	ENSG00000164949	GEM	ACC,BLCA,BRCA,HNSC,PAAD,SARC,UCEC,UCS		UCEC
ENSG00000272841	ENSG00000166147	FBN1	ACC,BLCA,CESC,HNSC,PAAD,STAD,TGCT,UCEC		UCEC
ENSG00000272841	ENSG00000174807	CD248	ACC,PAAD,STAD,TGCT,UCEC		UCEC
ENSG00000272841	ENSG00000178202	POGLUT3	ACC,PAAD,TGCT,THYM,UCEC		UCEC
ENSG00000272841	ENSG00000180447	GAS1	ACC,BLCA,ESCA,HNSC,PAAD,TGCT,UCEC		UCEC
ENSG00000272841	ENSG00000186340	THBS2	ACC,BLCA,BRCA,ESCA,PAAD,SARC,STAD,TGCT,UCEC	BRCA	UCEC
ENSG00000272841	ENSG00000189184	PCDH18	ACC,BLCA,HNSC,TGCT,THYM,UCEC		UCEC
ENSG00000272841	ENSG00000204262	COL5A2	ACC,BLCA,BRCA,CESC,ESCA,HNSC,PAAD,STAD,TGCT,UCEC	BRCA
ENSG00000272841	ENSG00000078098	FAP	BLCA,BRCA,ESCA,HNSC,PAAD,STAD,UCEC	BRCA	UCEC
ENSG00000272841	ENSG00000105989	WNT2	BLCA,ESCA,PAAD,STAD,UCEC		UCEC
ENSG00000272841	ENSG00000113140	SPARC	BLCA,BRCA,CESC,ESCA,HNSC,PAAD,STAD,TGCT,THCA,UCEC		UCEC
ENSG00000272841	ENSG00000123342	MMP19	BLCA,ESCA,PAAD,STAD,UCEC		UCEC
ENSG00000272841	ENSG00000134986	NREP	BLCA,BRCA,ESCA,HNSC,PAAD,TGCT	BRCA
ENSG00000272841	ENSG00000140937	CDH11	BLCA,BRCA,ESCA,HNSC,LGG,PAAD,STAD,TGCT,UCEC	BRCA	UCEC
ENSG00000272841	ENSG00000148848	ADAM12	BLCA,BRCA,ESCA,HNSC,PAAD,STAD	BRCA
ENSG00000272841	ENSG00000151692	RNF144A	BLCA,PAAD,STAD,TGCT,UCEC		UCEC
ENSG00000272841	ENSG00000162618	ADGRL4	BLCA,PAAD,TGCT,THCA,UCEC		UCEC
ENSG00000272841	ENSG00000166341	DCHS1	BLCA,HNSC,PAAD,STAD,TGCT,UCEC		UCEC
ENSG00000272841	ENSG00000173706	HEG1	BLCA,PAAD,STAD,TGCT,UCEC		UCEC
ENSG00000272841	ENSG00000176435	CLEC14A	BLCA,PAAD,STAD,TGCT,THCA,UCEC		UCEC
ENSG00000272841	ENSG00000182492	BGN	BLCA,BRCA,CESC,ESCA,HNSC,PAAD,STAD,TGCT,UCS	BRCA
ENSG00000272841	ENSG00000183722	LHFPL6	BLCA,CESC,PAAD,STAD,THYM,UCEC		UCEC
ENSG00000272841	ENSG00000183876	ARSI	BLCA,BRCA,HNSC,PAAD,STAD,TGCT	BRCA
ENSG00000272841	ENSG00000271601	LIX1L	BLCA,PAAD,TGCT,THYM,UCEC		UCEC
ENSG00000272841	ENSG00000105472	CLEC11A	BRCA,ESCA,HNSC,PAAD,STAD,TGCT	BRCA
ENSG00000272841	ENSG00000122641	INHBA	BRCA,ESCA,PAAD,STAD,TGCT,UCEC,UCS	BRCA
ENSG00000272841	ENSG00000123500	COL10A1	BRCA,ESCA,HNSC,PAAD,STAD	BRCA
ENSG00000272841	ENSG00000164484	TMEM200A	BRCA,PAAD,TGCT,UCEC,UCS		UCEC
ENSG00000272841	ENSG00000172061	LRRC15	BRCA,HNSC,PAAD,STAD,UCS	BRCA
ENSG00000272841	ENSG00000111897	SERINC1	CESC,TGCT,THYM,UCEC,UCS		UCEC
ENSG00000272841	ENSG00000123094	RASSF8	CESC,PAAD,TGCT,THYM,UCEC		UCEC
ENSG00000272841	ENSG00000255302	EID1	CESC,PAAD,TGCT,THCA,THYM,UCEC		UCEC

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID

LncRNA ENST ID

PC Gene Name

PC Gene ID

PC ENST ID

nDG

Cancer with PC gene up-regulation

Cancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000272841.1	ENST00000608721.1	141	422	0

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential