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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000272141

Summary for RP11-465B22.8

check button Gene summary

Gene informationEnsembl ID

ENSG00000272141

Gene symbol

RP11-465B22.8

Gene name
HGNC
Entrez ID
Gene typelincRNA
Synonyms
UniProtAcc

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Structure and expression level for RP11-465B22.8

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002721411.655667e+023.129824e+004.680190e-016.687387e+002.270000e-113.280000e-10UPCHOL
ENSG000002721411.455999e+021.155099e+002.202033e-015.245600e+001.560000e-076.540000e-07UPTHCA
ENSG000002721413.792292e+021.403173e+004.039633e-013.473516e+005.136870e-042.159207e-03UPBLCA
ENSG000002721414.891168e+022.844249e+007.413807e-013.836422e+001.248400e-041.458037e-03UPCESC
ENSG000002721413.633382e+021.909713e+002.323813e-018.218015e+002.070000e-162.480000e-15UPUCEC
ENSG000002721411.684682e+022.217965e+002.059684e-011.076848e+014.850000e-274.500000e-26UPLUSC
ENSG000002721411.428682e+021.123640e+001.306837e-018.598167e+008.100000e-184.710000e-17UPBRCA
ENSG000002721411.291973e+021.820408e+001.971119e-019.235404e+002.570000e-202.670000e-19UPLUAD
ENSG000002721414.522487e+021.267213e+001.830498e-016.922778e+004.430000e-123.020000e-11UPCOAD
ENSG000002721413.825268e+021.225358e+002.251320e-015.442844e+005.240000e-084.480000e-07UPSTAD
ENSG000002721415.254245e+022.138964e+003.545244e-016.033334e+001.610000e-093.940000e-08UPREAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002721415.354373e-011.506481e-04CHOL4.126874e-04
ENSG00000272141-4.454788e-011.216640e-05KICH2.587367e-05

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lncRNA-Protein interaction for RP11-465B22.8

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000272141ENST00000606993RP11-465B22.8ENSG00000155363MOV1059.0291.6058Q9HCE1RBP,EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000272141ENST00000606993RP11-465B22.8ENSG00000256223ZNF1014.992.7774P21506TFNA
ENSG00000272141ENST00000606993RP11-465B22.8ENSG00000197857ZNF448.5492.0603P15621TFNA
ENSG00000272141ENST00000606993RP11-465B22.8ENSG00000102878HSF46.8291.7765Q9ULV5TFNA
ENSG00000272141ENST00000606993RP11-465B22.8ENSG00000126456IRF32.7790.7237Q14653TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000272141ENST00000606993RP11-465B22.8ENSG00000155363MOV1059.0290.5997Q9HCE1RBP,EpiNA
ENSG00000272141ENST00000606993RP11-465B22.8ENSG00000141738GRB710.8890.2079Q14451RBPNA

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lncRNA-DNA interaction for RP11-465B22.8

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
PHF1,RBM6,HMGN3,ILF3,DDX49,RBM39,CENPT,ZNF10,TTC14,GMEB2,NOL3,MYPOP,HSF4,THOC6,RBM42,SRRM2,KLF16,IRF3,RBM5,CIRBP,SUGP1,DDX56,TIGD5,OVOL2,ZNF44,MZF1,HES1,CASZ1,SGSM2,ZXDC,ZNF84,RBM4B,DMTF1,TIGD1,GLI4,CPSF1,RBM10,RNPS1,DDX51,NR2F6,TRA2A,ZBTB3,MBD3,PCBP4,THAP3,SURF6,CENPB,DHX34,MBD6,FIZ1,ZGPAT,PPIE,PBX4,USF2,ZNF83,RALY,USF1,ASCL2,CXXC1,RNPC3,SNRPA,MNX1,SAFB2,THOC1,ZNF18,MOV10,DDX17
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-465B22.8

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
QKI,MBNL1,ATF1,IREB2
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000272141ENST00000606993exon_skip_2091chr1:17634547-17634562-8.65-0.6179ARHGEF10LENST00000361221In-frame
ENSG00000272141ENST00000606993exon_skip_44853chr10:104010815-104010908-13.51-0.1689SLKENST00000369755In-frame
ENSG00000272141ENST00000606993exon_skip_44998chr10:110132304-110132400-10.90-0.1434ADD3ENST00000356080In-frame
ENSG00000272141ENST00000606993exon_skip_48713chr10:34336198-34336243-9.60-0.3429PARD3ENST00000374789In-frame
ENSG00000272141ENST00000606993exon_skip_59476chr11:57815914-57816001-15.40-0.1974CTNND1ENST00000399050In-frame
ENSG00000272141ENST00000606993exon_skip_60345chr11:63903985-63904147-36.66-0.2477MARK2ENST00000402010In-frame
ENSG00000272141ENST00000606993exon_skip_64939chr11:112230207-112230230-6.91-0.3004PTSENST00000280362Frame-shift
ENSG00000272141ENST00000606993exon_skip_114200chr14:73279280-73279424-23.53-0.1769NUMBENST00000355058,ENST00000555238In-frame
ENSG00000272141ENST00000606993exon_skip_150188chr17:27643524-27643620-22.26-0.2748LGALS9ENST00000395473In-frame
ENSG00000272141ENST00000606993exon_skip_378912chr3:152446703-152446757-10.23-0.2558MBNL1ENST00000282486,ENST00000463374In-frame
ENSG00000272141ENST00000606993exon_skip_384879chr3:52554723-52554879-31.64-0.2244PBRM1ENST00000296302In-frame
ENSG00000272141ENST00000606993exon_skip_386291chr3:108050577-108050602-9.16-0.6543CD47ENST00000361309Frame-shift
ENSG00000272141ENST00000606993exon_skip_423795chr4:55888887-55888932-8.04-0.3496EXOC1ENST00000346134,ENST00000381295In-frame
ENSG00000272141ENST00000606993exon_skip_430601chr4:82842139-82842481-37.78-0.1173SEC31AENST00000355196,ENST00000395310,ENST00000448323In-frame
ENSG00000272141ENST00000606993exon_skip_456460chr6:17771113-17771218-18.26-0.2227KIF13AENST00000259711In-frame
ENSG00000272141ENST00000606993exon_skip_461111chr6:90544551-90544632-14.03-0.3897MAP3K7ENST00000369329In-frame
ENSG00000272141ENST00000606993exon_skip_435063chr5:66075023-66075230-20.71-0.1113ERBINENST00000284037In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000272141ENST00000606993exon_skip_21610chr1:9737497-9737554-9.67-0.1758CLSTN1ENST00000377298In-frame
ENSG00000272141ENST00000606993exon_skip_21628chr1:9756480-9756510-5.90-0.3933CLSTN1ENST00000377298In-frame
ENSG00000272141ENST00000606993exon_skip_33516chr1:156938417-156938513-21.40-0.3014ARHGEF11ENST00000361409In-frame
ENSG00000272141ENST00000606993exon_skip_133217chr16:8635038-8635079-15.66-0.4894METTL22ENST00000381920Frame-shift
ENSG00000272141ENST00000606993exon_skip_287874chr17:29085603-29085648-8.39-0.5593MYO18AENST00000527372In-frame
ENSG00000272141ENST00000606993exon_skip_309204chr19:49181348-49181461-24.64-0.2416TRPM4ENST00000252826Frame-shift
ENSG00000272141ENST00000606993exon_skip_340759chr2:85552415-85552567-18.62-0.1411GGCXENST00000233838Frame-shift
ENSG00000272141ENST00000606993exon_skip_351122chr20:36209487-36209898-46.08-0.1206EPB41L1ENST00000338074In-frame
ENSG00000272141ENST00000606993exon_skip_353131chr20:58669290-58669453-27.82-0.1806STX16ENST00000371141Frame-shift
ENSG00000272141ENST00000606993exon_skip_357772chr20:47659398-47659452-10.29-0.2189SULF2ENST00000359930,ENST00000484875In-frame
ENSG00000272141ENST00000606993exon_skip_361434chr21:25997359-25997416-11.29-0.3763APPENST00000346798In-frame
ENSG00000272141ENST00000606993exon_skip_368285chr22:29329711-29329720-3.05-0.3812AP1B1ENST00000357586,ENST00000405198In-frame
ENSG00000272141ENST00000606993exon_skip_376144chr3:100311832-100311877-9.55-0.3979TBC1D23ENST00000394144In-frame
ENSG00000272141ENST00000606993exon_skip_380242chr3:186784961-186785101-13.17-0.1304EIF4A2ENST00000323963Frame-shift
ENSG00000272141ENST00000606993exon_skip_382356chr3:37091466-37091538-10.91-0.1984LRRFIP2ENST00000336686In-frame
ENSG00000272141ENST00000606993exon_skip_382458chr3:38131595-38131638-10.69-0.5345ACAA1ENST00000333167Frame-shift
ENSG00000272141ENST00000606993exon_skip_451515chr6:41080810-41080897-17.66-0.2030NFYAENST00000341376In-frame
ENSG00000272141ENST00000606993exon_skip_508298chr9:136445051-136445111-8.91-0.1620SEC16AENST00000313050In-frame
ENSG00000272141ENST00000606993exon_skip_514511chrX:41555599-41555635-8.30-0.3773CASKENST00000378163In-frame
ENSG00000272141ENST00000606993exon_skip_515330chrX:65524563-65524614-10.12-0.4217LAS1LENST00000374811In-frame
ENSG00000272141ENST00000606993exon_skip_9446chr1:147270931-147271005-9.81-0.2180CHD1LENST00000369258Frame-shift
ENSG00000272141ENST00000606993exon_skip_41841chr10:68756272-68756483-25.96-0.1266CCAR1ENST00000265872Frame-shift
ENSG00000272141ENST00000606993exon_skip_66482chr11:126274926-126275021-14.26-0.1698FOXRED1ENST00000263578Frame-shift
ENSG00000272141ENST00000606993exon_skip_110959chr14:20372732-20372857-15.78-0.1422TEP1ENST00000262715Frame-shift
ENSG00000272141ENST00000606993exon_skip_111863chr14:23565815-23565892-15.18-0.2811AP1G2ENST00000308724,ENST00000397120Frame-shift
ENSG00000272141ENST00000606993exon_skip_300663chr19:1425877-1425960-11.14-0.1797DAZAP1ENST00000233078Frame-shift
ENSG00000272141ENST00000606993exon_skip_302168chr19:10680345-10680443-13.53-0.1990ILF3ENST00000590261Frame-shift
ENSG00000272141ENST00000606993exon_skip_353395chr20:62130218-62130296-13.44-0.2278LSM14BENST00000279068In-frame
ENSG00000272141ENST00000606993exon_skip_370518chr22:50247691-50247776-17.18-0.2291HDAC10ENST00000216271Frame-shift
ENSG00000272141ENST00000606993exon_skip_442657chr5:74730259-74730398-17.18-0.1701GFM2ENST00000296805,ENST00000509430Frame-shift
ENSG00000272141ENST00000606993exon_skip_470226chr7:103307595-103307708-11.27-0.1326PMPCBENST00000249269Frame-shift

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for RP11-465B22.8

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000272141.1ENST00000606993.128525882