lncRNA targets the enhancer region and positively regulates the gene expression. |
Only predicted by TDF | CXXC5,RNPS1,HES6,PCBP4,PATZ1,THOC6 | Exist in public source | NA |
lncRNA targets the promoter region and positively regulates the gene expression. |
lncRNA targets the promoter region and negatively regulates the gene expression. |
lncRNA targets the 3'UTR region and negatively regulates the mRNA. |
Only predicted by lncTar | MBNL1 | Exist in public source | NA |
lncRNA targets the skipped exon region. | -lncRNA and exonskipping events are positively correlated. |
![lncRNA and exonskipping events positive correlated](images/figure_exon/figure_pos/ENSG00000272079.svg) |
LncRNA Ensembl ID | LncRNA ENST ID | Exon ID | Skipped Exon | dG | ndG | Gene name with skipped exon | TransID with skipped exon | ORF mutation | ENSG00000272079 | ENST00000607794 | exon_skip_98384 | chr12:124327408-124327633 | -26.86 | -0.1249 | NCOR2 | ENST00000405201 | In-frame | ENSG00000272079 | ENST00000607794 | exon_skip_302779 | chr19:13078612-13078735 | -16.75 | -0.1595 | NFIX | ENST00000592199 | In-frame | ENSG00000272079 | ENST00000607794 | exon_skip_423795 | chr4:55888887-55888932 | -8.09 | -0.2697 | EXOC1 | ENST00000346134,ENST00000381295 | In-frame | ENSG00000272079 | ENST00000607794 | exon_skip_11259 | chr1:155061414-155061489 | -16.32 | -0.2473 | ADAM15 | ENST00000356955 | In-frame | ENSG00000272079 | ENST00000607794 | exon_skip_37475 | chr1:225504990-225505053 | -8.41 | -0.1716 | ENAH | ENST00000366844 | In-frame | ENSG00000272079 | ENST00000607794 | exon_skip_67074 | chr11:406842-406993 | -25.39 | -0.2098 | SIGIRR | ENST00000332725,ENST00000397632,ENST00000431843 | Frame-shift | ENSG00000272079 | ENST00000607794 | exon_skip_386291 | chr3:108050577-108050602 | -7.69 | -0.3845 | CD47 | ENST00000361309 | Frame-shift |
-lncRNA and exonskipping events are negatively correlated. |
LncRNA Ensembl ID | LncRNA ENST ID | Exon ID | Skipped Exon | dG | ndG | Gene name with skipped exon | TransID with skipped exon | LOF | ENSG00000272079 | ENST00000607794 | exon_skip_376144 | chr3:100311832-100311877 | -6.99 | -0.2056 | TBC1D23 | ENST00000394144 | In-frame | ENSG00000272079 | ENST00000607794 | exon_skip_382356 | chr3:37091466-37091538 | -7.06 | -0.8825 | LRRFIP2 | ENST00000336686 | In-frame |
lncRNA targets by miRNA. |
LncRNA Ensembl ID | miRNA ID | LncRNA ENST ID | Binding site in lncRNA | Score | Energy | Align Len | Public source | ENSG00000272079 | hsa-mir-22 | ENST00000607794 | chr16:3006250-3006337 | 186.00 | -83.83 | 78 | NA | ENSG00000272079 | hsa-mir-22 | ENST00000607794 | chr16:3006144-3006237 | 170.00 | -75.38 | 75 | NA | ENSG00000272079 | hsa-mir-22 | ENST00000607794 | chr16:3007168-3007247 | 165.00 | -68.97 | 79 | NA | ENSG00000272079 | hsa-mir-22 | ENST00000607794 | chr16:3006623-3006704 | 162.00 | -88.70 | 82 | NA | ENSG00000272079 | hsa-mir-22 | ENST00000607794 | chr16:3006413-3006488 | 156.00 | -82.15 | 80 | NA | ENSG00000272079 | hsa-mir-22 | ENST00000607794 | chr16:3006857-3006937 | 154.00 | -67.68 | 71 | NA | ENSG00000272079 | hsa-mir-22 | ENST00000607794 | chr16:3007263-3007347 | 153.00 | -80.28 | 86 | NA | ENSG00000272079 | hsa-mir-22 | ENST00000607794 | chr16:3007022-3007102 | 149.00 | -77.53 | 86 | NA | ENSG00000272079 | hsa-mir-22 | ENST00000607794 | chr16:3006931-3007004 | 147.00 | -81.11 | 82 | NA |
RNA A-to-I editing events in lncRNA. |
LncRNAediting ID | LncRNA Ensembl ID | Chromosome | Editing Position | Strand | Gene Type | Gene Name | Transcript ID | Transcript Type | Transcript Name | LncEditing_303781 | ENSG00000272079.2 | chr16 | 3006439 | + | lincRNA | LA16c-380H5.5 | ENST00000607794.2 | lincRNA | LA16c-380H5.5-001 | LncEditing_303787 | ENSG00000272079.2 | chr16 | 3006658 | + | lincRNA | LA16c-380H5.5 | ENST00000607794.2 | lincRNA | LA16c-380H5.5-001 |
Edited-associated DElncRNAs in cancer. |
LncRNA Ensembl ID | LncRNA Index | Cancer Type | Chr_Postion_Strand | AVE1 | AVE2 | log2FC | W-value | P-value | Adjc.p-value | Change | ENSG00000272079 | LncEditing_303781 | LGG | chr16_3006439_+ | 3.658635e+00 | 1.771395e+00 | 9.556399e-01 | 1.044128e+01 | 1.606375e-25 | 6.593608e-25 | UP | ENSG00000272079 | LncEditing_303781 | THCA | chr16_3006439_+ | 6.566733e+00 | 3.351577e+00 | 1.030571e+00 | 1.313034e+01 | 2.206600e-39 | 5.185511e-38 | UP | ENSG00000272079 | LncEditing_303781 | CHOL | chr16_3006439_+ | 8.020310e+00 | 3.946891e+00 | 9.775732e-01 | 3.525445e+00 | 4.227720e-04 | 2.620107e-03 | UP | ENSG00000272079 | LncEditing_303787 | CHOL | chr16_3006658_+ | 7.508985e+00 | 4.456498e+00 | 1.328537e+00 | 2.122382e+00 | 3.380569e-02 | 3.736418e-02 | UP | ENSG00000272079 | LncEditing_303787 | OV | chr16_3006658_+ | 4.198270e+00 | 3.486738e+00 | 3.732500e+00 | 3.286347e+00 | 1.014961e-03 | 1.107066e-03 | UP |
Correlation between RNA A-to-I editing events's frequecy and lncRNA expression. |
LncRNA Ensembl ID | LncRNA Index | Correlation | P-value | Adjc.p-value | ENSG00000272079 | LncEditing_303781 | -4.061698e-01 | 1.384213e-09 | 1.501871e-07 | ENSG00000272079 | LncEditing_303787 | -5.615838e-01 | 1.090509e-04 | 4.423187e-04 | ENSG00000272079 | LncEditing_303781 | -3.926078e-01 | 1.459258e-03 | 2.782905e-03 | ENSG00000272079 | LncEditing_303781 | -7.390854e-01 | 2.289065e-02 | 3.872876e-02 |
Cis-expression quantitative trait loci(cis-eQTL) of lncRNA. |
LncRNA Ensembl ID | LncRNA Name | SNP info | Number of Positive corelated Cancer | Positive corelated Cancer | Number of Negative corelated Cancer | Negative corelated Cancer |
lncRNA regulates differentially expressed genes by function as enhancer. |
LncRNA Ensembl ID | PC Gene ID | PC Gene Name | Positive correlated cancers | Cancer with PC gene up-regulation | Cancer with PC gene down-regulation |
LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5). |
lncRNA ID | TF ID | TF Name | PCgene ID | PCgene Name | Number of Cancer | Canaer Types |
LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5). |
lncRNA ID | TF ID | TF Name | PCgene ID | PCgene Name | Number of Cancer | Canaer Types |
LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region. |
LncRNA Ensembl ID | RBP ID | RBP Gene Name | Exon Skipping ID | Skipped Exon | EX Gene Name | EX Affected TransID | ORF_anno | Cancer Type |
LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region. |
LncRNA Ensembl ID | RBP ID | RBP Gene Name | Exon Skipping ID | Skipped Exon | EX Gene Name | EX Affected TransID | ORF_anno | Cancer Type |
lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region. |
LncRNA Ensembl ID | LncRNA ENST ID | PC Gene Name | PC Gene ID | PC ENST ID | dG | nDG | Cancer with PC gene up-regulation | Cancer with PC gene Down-regulation |
lncRNA regulates mRNA by competing the miRNA binding site with mRNA. |
LncRNA Ensembl ID | lncRNA-miRNA-mRNA | Cancer Types | ENSG00000272079 | LA16c-380H5.5,hsa-mir-22,ARL6IP6 | PCPG,KICH,THCA,LGG,KIRP | ENSG00000272079 | LA16c-380H5.5,hsa-mir-22,CERS5 | PCPG,KICH,THCA,LGG,KIRP | ENSG00000272079 | LA16c-380H5.5,hsa-mir-22,RCE1 | PCPG,KICH,THCA,LGG,KIRP | ENSG00000272079 | LA16c-380H5.5,hsa-mir-22,ZSWIM4 | PCPG,KICH,THCA,LGG,KIRP | ENSG00000272079 | LA16c-380H5.5,hsa-mir-22,EHMT2 | PCPG,KICH,THCA,LGG,KIRP | ENSG00000272079 | LA16c-380H5.5,hsa-mir-22,DPF2 | PCPG,KICH,THCA,LGG,KIRP | ENSG00000272079 | LA16c-380H5.5,hsa-mir-22,RBMX | PCPG,KICH,THCA,LGG,KIRP | ENSG00000272079 | LA16c-380H5.5,hsa-mir-22,SET | PCPG,KICH,THCA,LGG,KIRP | ENSG00000272079 | LA16c-380H5.5,hsa-mir-22,HMGB1 | PCPG,KICH,THCA,LGG,KIRP | ENSG00000272079 | LA16c-380H5.5,hsa-mir-22,RBM22 | PCPG,KICH,THCA,LGG,KIRP | ENSG00000272079 | LA16c-380H5.5,hsa-mir-22,KDM5B | PCPG,KICH,THCA,LGG,KIRP |
ORFfinder result for the gencode.v22.lncRNA.transcript.fa. |
lncRNA Ensembl ID | lncRNA ENST ID | length(AA) | start at transcript | end at transcript | ENSG00000272079.2 | ENST00000607794.2 | 138 | 194 | 607 |
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