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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000271869

Summary for DCTN6-DT

check button Gene summary

Gene informationEnsembl ID

ENSG00000271869

Gene symbol

DCTN6-DT

Gene nameDCTN6 divergent transcript
HGNC

55241

Entrez ID
Gene typelincRNA
Synonyms08p12|RP11-51J9.5|DCTN6-DT
UniProtAcc

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Structure and expression level for DCTN6-DT

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002718696.526297e+011.007026e+002.035631e-014.946997e+007.540000e-073.220000e-06UPUCEC

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002718694.695097e-011.138939e-03CHOL1.896607e-03
ENSG00000271869-4.681665e-013.720113e-06KICH8.977278e-06

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lncRNA-Protein interaction for DCTN6-DT

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for DCTN6-DT

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
SLIRP,GLI4,THAP4,MYPOP,IRF3,CIRBP,HES6,CENPB,SNRPA,LSM3,VAX2,LSM5,EIF3G,CENPT,ZGLP1,MRM1,SUGP1,DBP,LSM4,NR2F6,ZBTB3,CWC15,CPSF4,SF3B6,NELFE,IRF7,USF1,CXXC1,PHF1,THYN1,DEAF1,DDX49,HSF4,THOC6,RBM42,ZNF48,ATF4,REXO4,TIGD1,DDX51,MBD3,PCBP4,THAP3,MESP1,SRSF2,FIZ1,PBX4,ZNF18,ETV2,SOX12,HMGN3,E2F1,NOL3,THAP8,LSM2,PIN1,RBM8A,RRP7A,SMYD3,DDX41,XPA,THOC7,USF2,RALY,NR1H2
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.
Only predicted by TDF
ETV2,ZNF48,HSF4,RRP7A,EIF3G,LSM2,NOL3,CENPB,ZNF18,E4F1,THAP4,CXXC1,THAP7,RBM42,RBM6,SMYD3,PBX4,THAP3,CIRBP,SRP14
Exist in public source
NA

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.
Only predicted by TDF
ELF1,UBR5,GTF2I,AGO2,BAZ2A,DDX52,ATF1,SMAD1,SF3A1,ZNF45,TFCP2,FUBP1,REST,STAT3,DDX46,PATL1,BACH1,AGO4,ZMAT3,TEP1,CPSF2,FOXJ2,STAU1
Exist in public source
NA

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lncRNA-RNA interaction for DCTN6-DT

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
SMAD1,POGK,AGFG1,DHX8,BAZ2A,SMAD5,REST,PLS1,FUBP1,HBP1,AEBP2,BBX,TEP1,ELF1,ZNF28,PHF20,FOXN3,NOP9,DDX42,G3BP1,STAT6,NCBP1,SP2,AGO2,TFCP2,SART3,ELK4,STAT3,DDX6,KAT7,BPTF,CPSF2,ATF1,NCOA2,FOXK1,SRCAP,GLYR1,DDX3X,PUM1,DDX46,KDM2A,NR2C2,SLTM,NCOA3,SYNJ1,G3BP2,CREB1,DDX52,KLF13
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000271869ENST00000607315exon_skip_6457chr1:52083339-52083541-16.10-0.1376BTF3L4ENST00000313334Frame-shift
ENSG00000271869ENST00000607315exon_skip_514339chrX:23713134-23713208-6.24-0.1156ACOT9ENST00000336430Frame-shift
ENSG00000271869ENST00000607315exon_skip_5818chr1:45568484-45568684-18.62-0.1217AKR1A1ENST00000351829,ENST00000372070Frame-shift
ENSG00000271869ENST00000607315exon_skip_382458chr3:38131595-38131638-7.08-0.2360ACAA1ENST00000333167Frame-shift
ENSG00000271869ENST00000607315exon_skip_16568chr1:201989382-201989531-15.33-0.1080RNPEPENST00000295640Frame-shift
ENSG00000271869ENST00000607315exon_skip_29583chr1:114780109-114780215-10.14-0.1056SIKE1ENST00000060969Frame-shift
ENSG00000271869ENST00000607315exon_skip_41813chr10:68337857-68337996-16.24-0.1289HNRNPH3ENST00000265866Frame-shift
ENSG00000271869ENST00000607315exon_skip_53559chr10:101793912-101793998-9.89-0.1150OGAENST00000361464Frame-shift
ENSG00000271869ENST00000607315exon_skip_87733chr12:120571190-120571291-17.47-0.1859RNF10ENST00000325954Frame-shift
ENSG00000271869ENST00000607315exon_skip_95500chr12:96003837-96003920-10.06-0.1290LTA4HENST00000228740Frame-shift
ENSG00000271869ENST00000607315exon_skip_97655chr12:120579773-120579923-9.77-0.1191POP5ENST00000357500In-frame
ENSG00000271869ENST00000607315exon_skip_111863chr14:23565815-23565892-15.23-0.2417AP1G2ENST00000308724,ENST00000397120Frame-shift
ENSG00000271869ENST00000607315exon_skip_137309chr16:66558189-66558348-17.94-0.1188CKLFENST00000264001In-frame
ENSG00000271869ENST00000607315exon_skip_313557chr19:5786748-5786845-15.88-0.2301DUS3LENST00000309061Frame-shift
ENSG00000271869ENST00000607315exon_skip_319223chr19:43526200-43526349-22.65-0.1665ETHE1ENST00000292147Frame-shift
ENSG00000271869ENST00000607315exon_skip_324294chr2:27774423-27774530-11.91-0.1156MRPL33ENST00000296102Frame-shift
ENSG00000271869ENST00000607315exon_skip_370518chr22:50247691-50247776-14.37-0.1996HDAC10ENST00000216271Frame-shift
ENSG00000271869ENST00000607315exon_skip_436035chr5:79656957-79657001-8.67-0.3096TENT2ENST00000296783,ENST00000428308,ENST00000453514Frame-shift
ENSG00000271869ENST00000607315exon_skip_445390chr5:150403120-150403312-25.13-0.1470CD74ENST00000009530In-frame
ENSG00000271869ENST00000607315exon_skip_466137chr7:48103296-48103411-11.46-0.1158UPP1ENST00000331803,ENST00000395564Frame-shift
ENSG00000271869ENST00000607315exon_skip_470226chr7:103307595-103307708-12.98-0.1442PMPCBENST00000249269Frame-shift
ENSG00000271869ENST00000607315exon_skip_476549chr7:76013741-76013887-16.46-0.1372STYXL1ENST00000248600,ENST00000359697,ENST00000431581Frame-shift
ENSG00000271869ENST00000607315exon_skip_300022chr18:79919183-79919400-25.42-0.1304PQLC1ENST00000397778Frame-shift
ENSG00000271869ENST00000607315exon_skip_374581chr3:50110378-50110463-9.45-0.1432RBM5ENST00000347869Frame-shift
ENSG00000271869ENST00000607315exon_skip_326741chr2:73946718-73946906-14.21-0.1110DGUOKENST00000264093Frame-shift
ENSG00000271869ENST00000607315exon_skip_358606chr20:63202286-63203807-40.81-0.1094YTHDF1ENST00000370339In-frame
ENSG00000271869ENST00000607315exon_skip_52671chr10:97461495-97461622-13.52-0.1136MMS19ENST00000370782,ENST00000438925Frame-shift
ENSG00000271869ENST00000607315exon_skip_377198chr3:123130479-123130616-14.48-0.1089PDIA5ENST00000316218Frame-shift
ENSG00000271869ENST00000607315exon_skip_494079chr8:144099080-144099205-21.61-0.1831SHARPINENST00000398712Frame-shift
ENSG00000271869ENST00000607315exon_skip_371367chr3:9697710-9697866-17.41-0.1913MTMR14ENST00000296003In-frame
ENSG00000271869ENST00000607315exon_skip_52895chr10:98431130-98431291-19.42-0.1541HPS1ENST00000325103,ENST00000361490Frame-shift

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for DCTN6-DT

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000271869.1ENST00000607315.1105321638