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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000267751

Summary for BSG-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000267751

Gene symbol

BSG-AS1

Gene nameBSG antisense RNA 1
HGNC

55286

Entrez ID

105372233

Gene typeantisense
SynonymsBSG-AS1|19p13.3|AC009005.2
UniProtAcc

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Structure and expression level for BSG-AS1

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002677517.608641e+012.469958e+004.613792e-015.353423e+008.630000e-089.070000e-07UPGBM
ENSG000002677517.805150e+013.007688e+005.279457e-015.696963e+001.220000e-081.130000e-07UPCHOL
ENSG000002677516.357023e+011.228686e+001.200176e-011.023755e+011.350000e-242.730000e-23UPTHCA
ENSG000002677519.241966e+012.438873e+003.778693e-016.454275e+001.090000e-102.290000e-09UPBLCA
ENSG000002677511.660204e+022.554448e+002.415112e-011.057693e+013.810000e-269.820000e-25UPUCEC
ENSG000002677517.727295e+011.498685e+001.695954e-018.836829e+009.850000e-192.120000e-17UPPRAD
ENSG000002677519.196867e+011.586358e+001.986860e-017.984249e+001.410000e-157.160000e-15UPLUSC
ENSG000002677511.201165e+022.520961e+001.337542e-011.884771e+013.070000e-791.570000e-77UPBRCA
ENSG000002677511.091149e+022.099785e+001.603107e-011.309822e+013.370000e-391.080000e-37UPLUAD
ENSG000002677514.961052e+012.196134e+002.125992e-011.032993e+015.160000e-251.570000e-23UPLIHC
ENSG000002677511.203119e+021.271693e+002.327034e-015.464867e+004.630000e-084.000000e-07UPSTAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002677515.722020e-014.014861e-05CHOL1.604458e-04
ENSG000002677514.159198e-013.650823e-18LIHC1.266379e-16
ENSG000002677513.387720e-012.907691e-16PRAD2.943663e-15

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lncRNA-Protein interaction for BSG-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000267751ENST00000588290AC009005.2ENSG00000132780NASP44.6891.4275P49321EpiNA
ENSG00000267751ENST00000588290AC009005.2ENSG00000167670CHAF1A42.8692.3889Q13111EpiNA
ENSG00000267751ENST00000588290AC009005.2ENSG00000141570CBX841.4191.7367Q9HC52EpiNA
ENSG00000267751ENST00000588290AC009005.2ENSG00000116560SFPQ21.5292.0056P23246RBP,EpiNA
ENSG00000267751ENST00000588290AC009005.2ENSG00000277258PCGF221.491.6644P35227TF,EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000267751ENST00000589457AC009005.2ENSG00000125817CENPB7.7291.6168P07199TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000267751ENST00000588290AC009005.2ENSG00000116560SFPQ21.5291.1165P23246RBP,EpiNA

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lncRNA-DNA interaction for BSG-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for BSG-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
CLIP4,ATP2A2,MYCBP2,N4BP1,CAB39,HEATR5B,IDS,PTPN21,DYNC1LI2,SEPTIN10,KIDINS220,CYLD,DBR1,SNX1,DPP8,MCFD2,FER,MCC,PLSCR4,TRIP12
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000267751ENST00000588290exon_skip_44998chr10:110132304-110132400-9.22-0.1153ADD3ENST00000356080In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000267751ENST00000588290exon_skip_382356chr3:37091466-37091538-9.46-0.1660LRRFIP2ENST00000336686In-frame

check buttonlncRNA targets by miRNA.
lncRNA targets by miRNA
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source
ENSG00000267751hsa-mir-22ENST00000589457chr19:567642-567718175.00-62.2885NA
ENSG00000267751hsa-mir-22ENST00000589457chr19:567550-567639174.00-64.8193NA
ENSG00000267751hsa-mir-22ENST00000589457chr19:567345-567426161.00-77.2163NA
ENSG00000267751hsa-mir-22ENST00000589457chr19:567444-567529141.00-79.2286NA
ENSG00000267751hsa-mir-22ENST00000588908chr19:567574-567650175.00-62.2885NA
ENSG00000267751hsa-mir-22ENST00000588908chr19:567482-567571174.00-64.8193NA
ENSG00000267751hsa-mir-22ENST00000588908chr19:567253-567334161.00-81.9163NA
ENSG00000267751hsa-mir-22ENST00000590292chr19:567621-567697175.00-62.2885NA
ENSG00000267751hsa-mir-22ENST00000590292chr19:567529-567618174.00-64.8193NA
ENSG00000267751hsa-mir-22ENST00000590292chr19:567324-567405161.00-81.9163NA
ENSG00000267751hsa-mir-22ENST00000590292chr19:567423-567508141.00-79.2286NA
ENSG00000267751hsa-mir-22ENST00000588290chr19:567811-567887175.00-62.2885NA
ENSG00000267751hsa-mir-22ENST00000588290chr19:567719-567808174.00-64.8193NA
ENSG00000267751hsa-mir-22ENST00000588290chr19:567514-567595161.00-77.5163NA
ENSG00000267751hsa-mir-22ENST00000588290chr19:567411-567484142.00-82.5377NA
ENSG00000267751hsa-mir-22ENST00000588290chr19:567613-567698141.00-79.2286NA

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Variants for BSG-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation
ENSG00000267751ENST00000589457CLIP4ENSG00000115295ENST00000401617-0.2438172-GBM,BLCA,UCEC,PRAD,BRCA,STAD
ENSG00000267751ENST00000589457CLIP4ENSG00000115295ENST00000404424-0.1719464-GBM,BLCA,UCEC,PRAD,BRCA,STAD
ENSG00000267751ENST00000589457MCCENSG00000171444ENST00000624689-0.1181105-CHOL,UCEC,PRAD,LUAD,LIHC,STAD
ENSG00000267751ENST00000589457MCCENSG00000171444ENST00000514701-0.155996-CHOL,UCEC,PRAD,LUAD,LIHC,STAD
ENSG00000267751ENST00000589457PLSCR4ENSG00000114698ENST00000446574-0.1841263-CHOL,THCA,BLCA,UCEC,LUSC,BRCA,LUAD,LIHC
ENSG00000267751ENST00000589457PLSCR4ENSG00000114698ENST00000493382-0.1230300-CHOL,THCA,BLCA,UCEC,LUSC,BRCA,LUAD,LIHC
ENSG00000267751ENST00000589457CYLDENSG00000083799ENST00000564326-0.16591-GBM
ENSG00000267751ENST00000589457CYLDENSG00000083799ENST00000566206-0.1126171-GBM
ENSG00000267751ENST00000588908CLIP4ENSG00000115295ENST00000401617-0.243863-GBM,BLCA,UCEC,PRAD,BRCA,STAD
ENSG00000267751ENST00000588908CLIP4ENSG00000115295ENST00000404424-0.1719379-GBM,BLCA,UCEC,PRAD,BRCA,STAD
ENSG00000267751ENST00000588908MCCENSG00000171444ENST00000514701-0.130556-CHOL,UCEC,PRAD,LUAD,LIHC,STAD
ENSG00000267751ENST00000588908PLSCR4ENSG00000114698ENST00000493382-0.1380205-CHOL,THCA,BLCA,UCEC,LUSC,BRCA,LUAD,LIHC
ENSG00000267751ENST00000588908CYLDENSG00000083799ENST00000564326-0.163868-GBM
ENSG00000267751ENST00000588908CYLDENSG00000083799ENST00000566206-0.11821-GBM
ENSG00000267751ENST00000588908MYCBP2ENSG00000005810ENST00000466564-0.1945520-GBM,BRCA
ENSG00000267751ENST00000590292CLIP4ENSG00000115295ENST00000401617-0.243861-GBM,BLCA,UCEC,PRAD,BRCA,STAD
ENSG00000267751ENST00000590292CLIP4ENSG00000115295ENST00000404424-0.1719353-GBM,BLCA,UCEC,PRAD,BRCA,STAD
ENSG00000267751ENST00000590292MCCENSG00000171444ENST00000514701-0.132654-CHOL,UCEC,PRAD,LUAD,LIHC,STAD
ENSG00000267751ENST00000590292IDSENSG00000010404ENST00000428056-0.10081-GBM,UCEC
ENSG00000267751ENST00000590292PLSCR4ENSG00000114698ENST00000446574-0.1841152-CHOL,THCA,BLCA,UCEC,LUSC,BRCA,LUAD,LIHC
ENSG00000267751ENST00000590292PLSCR4ENSG00000114698ENST00000493382-0.1230189-CHOL,THCA,BLCA,UCEC,LUSC,BRCA,LUAD,LIHC
ENSG00000267751ENST00000590292CYLDENSG00000083799ENST00000566206-0.11821-GBM
ENSG00000267751ENST00000590292MYCBP2ENSG00000005810ENST00000466564-0.137867-GBM,BRCA
ENSG00000267751ENST00000588290CLIP4ENSG00000115295ENST00000401617-0.38691-GBM,BLCA,UCEC,PRAD,BRCA,STAD
ENSG00000267751ENST00000588290CLIP4ENSG00000115295ENST00000404424-0.691751-GBM,BLCA,UCEC,PRAD,BRCA,STAD
ENSG00000267751ENST00000588290MCCENSG00000171444ENST00000514701-0.1326136-CHOL,UCEC,PRAD,LUAD,LIHC,STAD
ENSG00000267751ENST00000588290PLSCR4ENSG00000114698ENST00000446574-0.1841234-CHOL,THCA,BLCA,UCEC,LUSC,BRCA,LUAD,LIHC
ENSG00000267751ENST00000588290PLSCR4ENSG00000114698ENST00000493382-0.129183-CHOL,THCA,BLCA,UCEC,LUSC,BRCA,LUAD,LIHC
ENSG00000267751ENST00000588290CYLDENSG00000083799ENST00000569418-0.11671-GBM
ENSG00000267751ENST00000588290CYLDENSG00000083799ENST00000564326-0.11671-GBM
ENSG00000267751ENST00000588290CYLDENSG00000083799ENST00000566206-0.152295-GBM
ENSG00000267751ENST00000588290CYLDENSG00000083799ENST00000398568-0.11671-GBM
ENSG00000267751ENST00000588290CYLDENSG00000083799ENST00000568704-0.11671-GBM
ENSG00000267751ENST00000588290MYCBP2ENSG00000005810ENST00000466564-0.1378149-GBM,BRCA

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types
ENSG00000267751BSG-AS1,hsa-mir-22,ZNF48CESC,CHOL,MESO,THYM,LIHC
ENSG00000267751BSG-AS1,hsa-mir-22,DHX30CESC,CHOL,MESO,THYM,LIHC
ENSG00000267751BSG-AS1,hsa-mir-22,EHMT2CESC,CHOL,MESO,THYM,LIHC
ENSG00000267751BSG-AS1,hsa-mir-22,MYL6BCESC,CHOL,MESO,THYM,LIHC
ENSG00000267751BSG-AS1,hsa-mir-22,CEP131CESC,CHOL,MESO,THYM,LIHC

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000267751.4ENST00000589457.1136442849
ENSG00000267751.4ENST00000588908.421282717
ENSG00000267751.4ENST00000590292.42036614
ENSG00000267751.4ENST00000588290.21714516