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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000267750

Summary for RUNDC3A-AS1

check button Gene summary

Gene informationEnsembl ID

ENSG00000267750

Gene symbol

RUNDC3A-AS1

Gene nameRUNDC3A antisense RNA 1
HGNC

51344

Entrez ID
Gene typeantisense
SynonymsRUNDC3A-AS1|17q21.31
UniProtAcc

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Structure and expression level for RUNDC3A-AS1

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002677504.399007e+021.970210e+001.023706e-011.924586e+011.530000e-825.630000e-80UPTHCA
ENSG000002677505.148139e+023.309584e+002.548548e-011.298616e+011.470000e-389.970000e-37UPKICH

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002677505.014968e-015.553145e-07KICH1.688994e-06
ENSG000002677503.074266e-017.453149e-14THCA8.229518e-13

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lncRNA-Protein interaction for RUNDC3A-AS1

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for RUNDC3A-AS1

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RUNDC3A-AS1

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation

-lncRNA and exonskipping events are negatively correlated.
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for RUNDC3A-AS1

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name
LncEditing_325483ENSG00000267750.4chr1744299767-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325488ENSG00000267750.4chr1744299815-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325489ENSG00000267750.4chr1744299818-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325490ENSG00000267750.4chr1744299821-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325491ENSG00000267750.4chr1744299827-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325492ENSG00000267750.4chr1744299834-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325494ENSG00000267750.4chr1744299861-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325495ENSG00000267750.4chr1744299871-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325496ENSG00000267750.4chr1744299874-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325497ENSG00000267750.4chr1744299875-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325498ENSG00000267750.4chr1744299883-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325505ENSG00000267750.4chr1744299970-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325507ENSG00000267750.4chr1744299978-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325508ENSG00000267750.4chr1744299980-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325510ENSG00000267750.4chr1744300193-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325529ENSG00000267750.4chr1744300878-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325548ENSG00000267750.4chr1744301213-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325549ENSG00000267750.4chr1744301230-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325557ENSG00000267750.4chr1744302116-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325562ENSG00000267750.4chr1744302151-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325579ENSG00000267750.4chr1744302270-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325586ENSG00000267750.4chr1744302321-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325657ENSG00000267750.4chr1744303568-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325669ENSG00000267750.4chr1744303608-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325671ENSG00000267750.4chr1744303612-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325675ENSG00000267750.4chr1744303621-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325677ENSG00000267750.4chr1744303622-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325715ENSG00000267750.4chr1744303711-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325731ENSG00000267750.4chr1744303757-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325733ENSG00000267750.4chr1744303763-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001
LncEditing_325745ENSG00000267750.4chr1744303856-antisenseRUNDC3A-AS1ENST00000588097.4antisenseRUNDC3A-AS1-001

check buttonEdited-associated DElncRNAs in cancer.
Differentially expressed gene
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange
ENSG00000267750LncEditing_325490KICHchr17_44299821_-2.191211e+001.613579e+002.265191e+002.439977e+001.468819e-021.827281e-02UP
ENSG00000267750LncEditing_325491KICHchr17_44299827_-2.382073e+001.637189e+001.848441e+002.537907e+001.115178e-021.489279e-02UP
ENSG00000267750LncEditing_325494KICHchr17_44299861_-2.486800e+001.671033e+001.743525e+002.449365e+001.431084e-021.785651e-02UP
ENSG00000267750LncEditing_325495KICHchr17_44299871_-2.361851e+001.416331e+001.355456e+004.459537e+008.213685e-064.401693e-05UP
ENSG00000267750LncEditing_325496KICHchr17_44299874_-2.415918e+001.671690e+001.882303e+002.941977e+003.261236e-035.641541e-03UP
ENSG00000267750LncEditing_325497KICHchr17_44299875_-2.356952e+001.309560e+001.179468e+004.623182e+003.778974e-062.289292e-05UP
ENSG00000267750LncEditing_325498KICHchr17_44299883_-2.390783e+001.368882e+001.243031e+004.464457e+008.027194e-064.357619e-05UP
ENSG00000267750LncEditing_325507KICHchr17_44299978_-2.355688e+001.368767e+001.276696e+004.262564e+002.020945e-058.799529e-05UP
ENSG00000267750LncEditing_325508KICHchr17_44299980_-2.577110e+001.685653e+001.632796e+003.285863e+001.016703e-032.083245e-03UP
ENSG00000267750LncEditing_325529KICHchr17_44300878_-3.120595e+001.625014e+001.062283e+004.113424e+003.898338e-051.454915e-04UP
ENSG00000267750LncEditing_325548KICHchr17_44301213_-2.518077e+001.394066e+001.172301e+004.961511e+006.994686e-076.644952e-06UP
ENSG00000267750LncEditing_325549KICHchr17_44301230_-2.534529e+001.531256e+001.375512e+003.987515e+006.676886e-052.197589e-04UP
ENSG00000267750LncEditing_325557KICHchr17_44302116_-2.998686e+001.592795e+001.095566e+004.218182e+002.462802e-051.028101e-04UP
ENSG00000267750LncEditing_325562KICHchr17_44302151_-2.985669e+001.643951e+001.161593e+003.414541e+006.388955e-041.428119e-03UP
ENSG00000267750LncEditing_325579KICHchr17_44302270_-2.619597e+001.678825e+001.557892e+002.602100e+009.265488e-031.269827e-02UP
ENSG00000267750LncEditing_325586KICHchr17_44302321_-2.447744e+001.409924e+001.256541e+004.449719e+008.598268e-064.549463e-05UP
ENSG00000267750LncEditing_325657KICHchr17_44303568_-2.697075e+001.647633e+001.406469e+003.381818e+007.200779e-041.584171e-03UP
ENSG00000267750LncEditing_325669KICHchr17_44303608_-2.692890e+001.470607e+001.145812e+005.145654e+002.665902e-073.461161e-06UP
ENSG00000267750LncEditing_325671KICHchr17_44303612_-2.634349e+001.693259e+001.568273e+002.296329e+002.165709e-022.528677e-02UP
ENSG00000267750LncEditing_325675KICHchr17_44303621_-2.643456e+001.691981e+001.553490e+003.134988e+001.718611e-033.250586e-03UP
ENSG00000267750LncEditing_325677KICHchr17_44303622_-2.682274e+001.547129e+001.259664e+004.110474e+003.948470e-051.460585e-04UP
ENSG00000267750LncEditing_325731KICHchr17_44303757_-2.563787e+001.687794e+001.657998e+002.165251e+003.036847e-023.358207e-02UP
ENSG00000267750LncEditing_325733KICHchr17_44303763_-2.441102e+001.619481e+001.689186e+002.911586e+003.595988e-036.085519e-03UP
ENSG00000267750LncEditing_325745KICHchr17_44303856_-2.317351e+001.694007e+002.212207e+002.485464e+001.293828e-021.679565e-02UP
ENSG00000267750LncEditing_325483THCAchr17_44299767_-2.130785e+001.300609e+001.404105e+007.218297e+005.264249e-131.161176e-12UP
ENSG00000267750LncEditing_325488THCAchr17_44299815_-1.876122e+001.082429e+001.260269e+001.249405e+018.044986e-361.068584e-34UP
ENSG00000267750LncEditing_325489THCAchr17_44299818_-1.854128e+001.239673e+001.721818e+008.839701e+009.597547e-193.313051e-18UP
ENSG00000267750LncEditing_325490THCAchr17_44299821_-1.866830e+001.042062e+001.188849e+001.307063e+014.845974e-391.020997e-37UP
ENSG00000267750LncEditing_325491THCAchr17_44299827_-1.894998e+001.173003e+001.445110e+001.070864e+019.271110e-276.437100e-26UP
ENSG00000267750LncEditing_325492THCAchr17_44299834_-1.938820e+001.332451e+001.848100e+005.715590e+001.093239e-081.860638e-08UP
ENSG00000267750LncEditing_325494THCAchr17_44299861_-1.981864e+001.276932e+001.576849e+008.185867e+002.703493e-167.577222e-16UP
ENSG00000267750LncEditing_325495THCAchr17_44299871_-2.011511e+001.205650e+001.354154e+001.000151e+011.500844e-237.905309e-23UP
ENSG00000267750LncEditing_325496THCAchr17_44299874_-2.004703e+001.285553e+001.560065e+007.823515e+005.136827e-151.296943e-14UP
ENSG00000267750LncEditing_325497THCAchr17_44299875_-2.057114e+001.187881e+001.262259e+001.066509e+011.482521e-261.017776e-25UP
ENSG00000267750LncEditing_325498THCAchr17_44299883_-2.123244e+001.208636e+001.230178e+001.057780e+013.777041e-262.455077e-25UP
ENSG00000267750LncEditing_325505THCAchr17_44299970_-2.239686e+001.288406e+001.253589e+009.093477e+009.592145e-203.686038e-19UP
ENSG00000267750LncEditing_325507THCAchr17_44299978_-2.021984e+001.118917e+001.171416e+001.289488e+014.810323e-388.949008e-37UP
ENSG00000267750LncEditing_325510THCAchr17_44300193_-1.610787e+001.320279e+003.485257e+005.533249e+003.143524e-085.149311e-08UP
ENSG00000267750LncEditing_325548THCAchr17_44301213_-2.278687e+001.245463e+001.147419e+001.047344e+011.144130e-256.921419e-25UP
ENSG00000267750LncEditing_325549THCAchr17_44301230_-2.255143e+001.283956e+001.230583e+008.948384e+003.607245e-191.304158e-18UP
ENSG00000267750LncEditing_325669THCAchr17_44303608_-2.049890e+001.263025e+001.431304e+008.549939e+001.231535e-173.800342e-17UP
ENSG00000267750LncEditing_325675THCAchr17_44303621_-2.160670e+001.301908e+001.368266e+007.958685e+001.738778e-154.619102e-15UP
ENSG00000267750LncEditing_325677THCAchr17_44303622_-2.189193e+001.228739e+001.200162e+001.048617e+011.000018e-256.171825e-25UP
ENSG00000267750LncEditing_325715THCAchr17_44303711_-2.241719e+001.298728e+001.269831e+008.333463e+007.851147e-172.273484e-16UP
ENSG00000267750LncEditing_325731THCAchr17_44303757_-2.148510e+001.316741e+001.415698e+007.320279e+002.474551e-135.599818e-13UP
ENSG00000267750LncEditing_325733THCAchr17_44303763_-2.157057e+001.282781e+001.333707e+008.033190e+009.497019e-162.578968e-15UP
ENSG00000267750LncEditing_325745THCAchr17_44303856_-2.067157e+001.313663e+001.528930e+006.477669e+009.315049e-111.801106e-10UP

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value
ENSG00000267750LncEditing_325488-3.742483e-012.197516e-081.828333e-07
ENSG00000267750LncEditing_325492-3.797652e-011.807617e-032.198739e-03
ENSG00000267750LncEditing_325494-3.995066e-015.522813e-051.137371e-04
ENSG00000267750LncEditing_325496-3.035177e-014.044347e-034.752679e-03
ENSG00000267750LncEditing_325498-3.236790e-014.990326e-047.309810e-04
ENSG00000267750LncEditing_325549-3.337060e-016.177453e-036.902035e-03
ENSG00000267750LncEditing_325675-4.771591e-016.705156e-051.291363e-04
ENSG00000267750LncEditing_325677-3.430347e-016.228868e-048.874003e-04
ENSG00000267750LncEditing_325731-3.744278e-014.112240e-034.805315e-03
ENSG00000267750LncEditing_325549-4.831861e-014.222374e-024.222374e-02
ENSG00000267750LncEditing_325671-8.246480e-011.176889e-022.858159e-02

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000267750.4ENST00000588097.4214939295
ENSG00000267750.4ENST00000586388.116045034985