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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000267100

Summary for ILF3-DT

check button Gene summary

Gene informationEnsembl ID

ENSG00000267100

Gene symbol

ILF3-DT

Gene nameILF3 divergent transcript
HGNC

27115

Entrez ID

147727

Gene typelincRNA
SynonymsILF3-AS1|19p13.2|ILF3-DT
UniProtAcc

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Structure and expression level for ILF3-DT

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002671001.100403e+03-1.772738e+004.340921e-01-4.083784e+004.430000e-056.239880e-04DOWNCESC

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002671005.813931e-012.812888e-05CHOL1.292699e-04

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lncRNA-Protein interaction for ILF3-DT

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for ILF3-DT

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
CHTOP,LSM5,SOX12,PHF1,RBM6,SLIRP,HMGN3,EIF3G,THYN1,KHDC1,RBM48,DEAF1,E2F1,DDX49,GLI4,THAP4,CENPT,GMEB2,MYPOP,HSF4,THOC6,RBM42,RBM5,IRF3,CIRBP,MRM1,SUGP1,DDX56,THAP8,LSM2,NFYB,ZNF44,MZF1,ZNF48,NRF1,RBM23,RBM4B,PIN1,THOC5,CREB3,TRUB2,REXO4,RXRB,TIGD1,RBM10,NRL,RNPS1,ERAL1,DDX51,RBM8A,ZBTB3,MBD3,GZF1,RRP7A,PCBP4,SMYD3,THAP3,CWC15,ZNF77,SURF6,NAIF1,APEX1,HINFP,XPA,FIZ1,PPIE,USF2,SF3B6,ZMAT1,NELFE,ZNF83,RALY,USF1,CXXC1,ZNF3,NR1H2,SNRPA,ZNF34,NXF1,SAFB2,PATZ1,LSM3,ZNF18
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.
Only predicted by TDF
CWC15,THOC5,ZNF48,RRP7A,MZF1,EIF3G,LSM2,ZNF18,E4F1,THAP4,CXXC1,ZMAT1,THAP7,RNPS1,SRSF5,ZNF3,ZNF83,RBM42,DHX30,RBM6,SMYD3,THAP3,CIRBP,SRP14
Exist in public source
NA

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for ILF3-DT

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.
Only predicted by lncTar
ELF1,AGFG1,ATF1
Exist in public source
NA

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000267100ENST00000591501exon_skip_349689chr20:25221231-25221333-13.20-0.1650ENTPD6ENST00000376652In-frame
ENSG00000267100ENST00000591501exon_skip_421737chr4:3428557-3428711-14.65-0.1191RGS12ENST00000336727,ENST00000344733Frame-shift

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000267100ENST00000591501exon_skip_83404chr12:53465931-53465973-15.38-0.4047PCBP2ENST00000439930In-frame
ENSG00000267100ENST00000591501exon_skip_148110chr17:4892401-4892512-20.92-0.2012MINK1ENST00000355280In-frame
ENSG00000267100ENST00000591501exon_skip_501752chr9:136992924-136992974-13.01-0.4337PAXXENST00000371620Frame-shift
ENSG00000267100ENST00000591501exon_skip_382458chr3:38131595-38131638-8.83-0.4906ACAA1ENST00000333167Frame-shift
ENSG00000267100ENST00000591501exon_skip_16568chr1:201989382-201989531-17.05-0.1160RNPEPENST00000295640Frame-shift
ENSG00000267100ENST00000591501exon_skip_81540chr12:42384939-42384996-12.23-0.3397PPHLN1ENST00000395568In-frame
ENSG00000267100ENST00000591501exon_skip_131398chr15:101286213-101286293-14.54-0.2384SNRPA1ENST00000254193Frame-shift
ENSG00000267100ENST00000591501exon_skip_324294chr2:27774423-27774530-13.14-0.1327MRPL33ENST00000296102Frame-shift
ENSG00000267100ENST00000591501exon_skip_331506chr2:181920596-181920662-11.40-0.2591ITPRID2ENST00000431877In-frame
ENSG00000267100ENST00000591501exon_skip_370518chr22:50247691-50247776-14.22-0.2031HDAC10ENST00000216271Frame-shift
ENSG00000267100ENST00000591501exon_skip_372419chr3:32449453-32449552-13.56-0.1507CMTM7ENST00000334983In-frame
ENSG00000267100ENST00000591501exon_skip_466113chr7:48099669-48099787-10.57-0.1068UPP1ENST00000331803,ENST00000395564Frame-shift
ENSG00000267100ENST00000591501exon_skip_481821chr8:22067084-22067159-19.66-0.3277DMTNENST00000265800,ENST00000358242,ENST00000432128,ENST00000523266In-frame
ENSG00000267100ENST00000591501exon_skip_309977chr19:49667018-49667161-20.51-0.1566BCL2L12ENST00000246785Frame-shift
ENSG00000267100ENST00000591501exon_skip_319223chr19:43526200-43526349-22.33-0.1758ETHE1ENST00000292147Frame-shift
ENSG00000267100ENST00000591501exon_skip_493445chr8:143586218-143586290-14.02-0.2298EEF1DENST00000317198,ENST00000395119,ENST00000419152,ENST00000529272In-frame
ENSG00000267100ENST00000591501exon_skip_41841chr10:68756272-68756483-23.21-0.1166CCAR1ENST00000265872Frame-shift
ENSG00000267100ENST00000591501exon_skip_87733chr12:120571190-120571291-14.34-0.1576RNF10ENST00000325954Frame-shift
ENSG00000267100ENST00000591501exon_skip_95500chr12:96003837-96003920-9.15-0.1158LTA4HENST00000228740Frame-shift
ENSG00000267100ENST00000591501exon_skip_74009chr11:64773429-64773505-13.70-0.1827SF1ENST00000377390Frame-shift
ENSG00000267100ENST00000591501exon_skip_83419chr12:53467804-53467843-8.94-0.3438PCBP2ENST00000439930In-frame
ENSG00000267100ENST00000591501exon_skip_374375chr3:49675182-49675309-16.82-0.1699APEHENST00000296456Frame-shift
ENSG00000267100ENST00000591501exon_skip_509447chrX:19354490-19354583-15.18-0.1807PDHA1ENST00000422285In-frame
ENSG00000267100ENST00000591501exon_skip_361485chr21:29008239-29008307-12.69-0.1952RWDD2BENST00000493196Frame-shift

check buttonlncRNA targets by miRNA.
lncRNA targets by miRNA
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source
ENSG00000267100hsa-mir-22ENST00000591501chr19:10652830-10652918186.00-78.3788NA
ENSG00000267100hsa-mir-22ENST00000591501chr19:10653355-10653435185.00-72.7285NA
ENSG00000267100hsa-mir-22ENST00000591501chr19:10651883-10651964184.00-77.6680NA
ENSG00000267100hsa-mir-22ENST00000591501chr19:10652469-10652562176.00-79.5689NA
ENSG00000267100hsa-mir-22ENST00000591501chr19:10652332-10652419175.00-69.3688NA
ENSG00000267100hsa-mir-22ENST00000591501chr19:10652234-10652317173.00-80.6884NA
ENSG00000267100hsa-mir-22ENST00000591501chr19:10653011-10653092171.00-83.5885NA
ENSG00000267100hsa-mir-22ENST00000591501chr19:10653692-10653765170.00-57.3477NA
ENSG00000267100hsa-mir-22ENST00000591501chr19:10652722-10652827163.00-104.07103NA
ENSG00000267100hsa-mir-22ENST00000591501chr19:10653215-10653300163.00-83.5188NA
ENSG00000267100hsa-mir-22ENST00000591501chr19:10652070-10652150162.00-82.3285NA
ENSG00000267100hsa-mir-22ENST00000591501chr19:10653596-10653671154.00-74.5273NA
ENSG00000267100hsa-mir-22ENST00000591501chr19:10652644-10652730140.00-78.3754NA
ENSG00000267100hsa-mir-146bENST00000591501chr19:10652725-10652808158.00-78.5181NA
ENSG00000267100hsa-mir-146bENST00000591501chr19:10653632-10653707156.00-61.8077NA
ENSG00000267100hsa-mir-146bENST00000591501chr19:10653779-10653845154.00-51.4066NA
ENSG00000267100hsa-mir-146bENST00000591501chr19:10653556-10653635153.00-64.4574NA
ENSG00000267100hsa-mir-146bENST00000591501chr19:10652446-10652516152.00-63.5772NA
ENSG00000267100hsa-mir-146bENST00000591501chr19:10653236-10653311148.00-67.8472NA
ENSG00000267100hsa-mir-146bENST00000591501chr19:10652275-10652345147.00-68.9767NA
ENSG00000267100hsa-mir-146bENST00000591501chr19:10651933-10652007146.00-70.6173NA
ENSG00000267100hsa-mir-146bENST00000591501chr19:10652564-10652636144.00-75.2169NA
ENSG00000267100hsa-mir-146bENST00000591501chr19:10651863-10651915141.00-53.8666NA
ENSG00000267100hsa-mir-146bENST00000591501chr19:10652505-10652575141.00-63.1269NA
ENSG00000267100hsa-mir-146bENST00000591501chr19:10653032-10653099140.00-64.7769NA
ENSG00000267100hsa-mir-146bENST00000591501chr19:10653151-10653220140.00-54.6766NA

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Variants for ILF3-DT

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types
ENSG00000267100ILF3-DT,hsa-mir-146b,PRPSAP2THCA,GBM,DLBC,PAAD,SARC
ENSG00000267100ILF3-DT,hsa-mir-22,RXRBKICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,ATAT1KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,TADA2AKICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,NRF1KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,RING1KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,EHMT2KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,PHC1KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,HEXIM2KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,VEZF1KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,PAXBP1KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,CNNM3KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,HEXDKICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,MBTD1KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,KPNA5KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,SBK1KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,RBMXKICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,C14orf93KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,MKS1KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,PCIF1KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,DET1KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,ING4KICH,CESC,CHOL,LGG,KIRP
ENSG00000267100ILF3-DT,hsa-mir-22,NSMCE4AKICH,CESC,CHOL,LGG,KIRP

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000267100.1ENST00000591501.135334227