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lncRNA: ENSG00000261437

Summary for LINC02894

Gene summary

Gene information	Ensembl ID	ENSG00000261437
	Gene symbol	LINC02894
	Gene name	long intergenic non-protein coding RNA 2894
	HGNC	55364
	Entrez ID	100288748
	Gene type	antisense
	Synonyms	LINC02894\|08q22.1\|RP11-22C11.2
	UniProtAcc

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Structure and expression level for LINC02894

AS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.

Differentially expressed gene analysis between cancer and normal samples.

Ensembl ID	Base mean	log2FC(AD/control)	lfcSE	Stat	P-value	Adjc.p-value	DEG direction	Cancer type
ENSG00000261437	8.506604e+01	4.649073e+00	5.385843e-01	8.632025e+00	6.030000e-18	2.240000e-16	UP	CHOL
ENSG00000261437	1.586293e+02	1.799674e+00	3.161806e-01	5.691916e+00	1.260000e-08	1.710000e-07	UP	BLCA
ENSG00000261437	1.436303e+02	3.867649e+00	6.273485e-01	6.165073e+00	7.050000e-10	4.040000e-08	UP	CESC
ENSG00000261437	9.053784e+01	1.846147e+00	1.756205e-01	1.051214e+01	7.600000e-26	1.920000e-24	UP	UCEC
ENSG00000261437	1.380517e+02	1.355571e+00	1.564465e-01	8.664758e+00	4.520000e-18	2.640000e-17	UP	LUSC
ENSG00000261437	1.866845e+02	1.681785e+00	1.083732e-01	1.551846e+01	2.600000e-54	6.350000e-53	UP	BRCA
ENSG00000261437	1.502116e+02	1.304550e+00	1.970097e-01	6.621756e+00	3.550000e-11	5.460000e-10	UP	STAD

Correlation between lncRNAs and cancer stages.

LncRNA Ensembl ID	Correlation	P-value	Cancer Type	Adjc.p-value
ENSG00000261437	5.771155e-01	3.323875e-05	CHOL	1.441304e-04
ENSG00000261437	3.225359e-01	8.345815e-15	PRAD	6.208780e-14
ENSG00000261437	3.014237e-01	8.548871e-14	UCEC	6.015872e-13

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lncRNA-Protein interaction for LINC02894

lncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

lncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

lncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).

LncRNA Ensembl ID

LncRNA ENST ID

LncRNA Name

Protein Ensembl ID

Protein Name

CatRAPID Score

Lncpro Score

UniPortID

Gene Subtype

Public source

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lncRNA-DNA interaction for LINC02894

lncRNA targets the enhancer region and positively regulates the gene expression.

Only predicted by TDF

LRRC14,TMEM168,ATAT1,OARD1,STMN1,PEX2,ZNF16,MPHOSPH10,ERI2,GLI4,RBM39,DPY19L3,TRIQK,CSPP1,OVOL2,TMEM14B,NRF1,C1orf56,LACTB2,DMTF1,AZIN1,CHCHD7,MKS1,SASS6,TAF4,NDUFAF6,SPIN3,TMED4,PIGC,SLX4IP,C20orf96,DDX55,GRHL2,PIGW,HJURP,EPCAM,MIS18A,AFTPH,GATAD1,STK3,MRPS28,DHFR2,ENY2,METTL21A,WDR5B,BARD1,FAM136A,MSANTD2,PTK2,THOC1,RECQL5,PAN3,FAM200A,UQCRB,PIGM,STRBP,AIMP1,CHTOP,VIRMA,TATDN1,POLR2K,COPS5,LSM5,DSCC1,STAU2,IFT74,SAMD12,C1GALT1C1,SUDS3,GKAP1,PUF60,ARL6IP1,DPY19L4,MRPL13,CTPS2,ABHD12,DNAJC2,PLA2G6,C21orf58,CBX3,BCLAF3,ADNP,WDSUB1,TEFM,CEBPZOS,MPLKIP,RHPN1,ENDOV,GGCT,DPY30,IFT80,HMGB1,ESRP1,UBR5,METTL23,ZNF34,GABPB1,H3-3A,ANKRD46,PATZ1,SS18L1,ZFAND1,TRIM45,OFD1,ACYP1,GEMIN6,DCAF13,ELOC,PABIR2,NBPF11,ATP6V1C1,DYNLT2,CFAP298,ZC3H8,C8orf33,TPD52,CAMKMT,EIF2AK1,OTUD6B,FANCF,MCM8,PAXBP1,DNAJC19,UTP23,RAD21,COIL,GMCL1,TMEM186,H2BC21,TADA2A,ZBED8,ORMDL1,MEAF6,COQ7,NEK8,TIGD1,RBM45,YAE1,DONSON,CENPS,PMS1,ATAD2,SRSF2,CHRAC1,TTC32,TSEN54,YWHAZ,TIA1,TCEA1,ZNF720,UPF3B,RMDN1,CCDC191,ZNF3,TMEM230,SPATA33,ACP6,PAN2,RAB2A,ARHGAP39,VSIG10,TMEM68,C2orf68,COX6C,MRE11,SAYSD1,SETD4,SPIRE2,GK5,TRMT13,TPRKB,MRPL15,DUSP28,ARHGAP12,PALM3,C8orf37,BOLA1,ARFGEF1,NFYB,MKRN1,MBTD1,BCDIN3D,PNN,COA5,DSN1,ZNF84,CCAR1,PSME3IP1,CBX8,TRA2A,ORC6,ARMC1,PCMTD1,KHDC4,THOC7,TBC1D31,SIX4,TSPAN6,C8orf76,RALY,CHMP4C,SMIM19

Exist in public source

lncRNA targets the promoter region and positively regulates the gene expression.

Only predicted by TDF

MAGEF1,PCMTD1,PDIK1L,C21orf59,GPR160,APITD1,COMMD3,MPHOSPH10,C1orf56,ARMC1,TIA1,UBR5,E4F1,FAM122B,METTL21A,LACTB2,SAYSD1,TCEA1,ZFAND1,CTPS2,IFT74,SPIN3,COIL,AIMP1,KIAA0907,CHMP4C,TERF1,ZNF720,CEBPZOS,ABHD12,ZNF3,ANKRD46,SETD4,UBE2V2,ADNP,PAN3,CHCHD7,CHRAC1,MPLKIP,C8orf76,C2orf68,PRPF3,ACP6,STK3,ARL6IP1,COQ7,TRA2A,COPS5

Exist in public source

lncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for LINC02894

lncRNA targets the 3'UTR region and negatively regulates the mRNA.

Only predicted by lncTar

C1R,EHD2,PML

Exist in public source

lncRNA targets the skipped exon region.

-lncRNA and exonskipping events are positively correlated.

lncRNA and exonskipping events positive correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	ORF mutation
ENSG00000261437	ENST00000562760	exon_skip_37475	chr1:225504990-225505053	-11.29	-0.1851	ENAH	ENST00000366844	In-frame
ENSG00000261437	ENST00000562760	exon_skip_44853	chr10:104010815-104010908	-14.39	-0.2116	SLK	ENST00000369755	In-frame
ENSG00000261437	ENST00000562760	exon_skip_44998	chr10:110132304-110132400	-12.35	-0.1583	ADD3	ENST00000356080	In-frame
ENSG00000261437	ENST00000562760	exon_skip_98384	chr12:124327408-124327633	-35.73	-0.1842	NCOR2	ENST00000405201	In-frame
ENSG00000261437	ENST00000562760	exon_skip_386291	chr3:108050577-108050602	-7.84	-0.4126	CD47	ENST00000361309	Frame-shift
ENSG00000261437	ENST00000562760	exon_skip_423795	chr4:55888887-55888932	-8.26	-0.2232	EXOC1	ENST00000346134,ENST00000381295	In-frame
ENSG00000261437	ENST00000562760	exon_skip_456460	chr6:17771113-17771218	-14.41	-0.1501	KIF13A	ENST00000259711	In-frame
ENSG00000261437	ENST00000562760	exon_skip_461111	chr6:90544551-90544632	-15.45	-0.1931	MAP3K7	ENST00000369329	In-frame

-lncRNA and exonskipping events are negatively correlated.

lncRNA and exonskipping events negative correlated

LncRNA Ensembl ID	LncRNA ENST ID	Exon ID	Skipped Exon	dG	ndG	Gene name with skipped exon	TransID with skipped exon	LOF
ENSG00000261437	ENST00000562760	exon_skip_21610	chr1:9737497-9737554	-11.21	-0.2288	CLSTN1	ENST00000377298	In-frame
ENSG00000261437	ENST00000562760	exon_skip_33516	chr1:156938417-156938513	-18.08	-0.2411	ARHGEF11	ENST00000361409	In-frame
ENSG00000261437	ENST00000562760	exon_skip_48327	chr10:26771074-26771089	-7.55	-0.5393	ABI1	ENST00000376142	In-frame
ENSG00000261437	ENST00000562760	exon_skip_351122	chr20:36209487-36209898	-45.96	-0.1140	EPB41L1	ENST00000338074	In-frame
ENSG00000261437	ENST00000562760	exon_skip_368285	chr22:29329711-29329720	-3.53	-0.5043	AP1B1	ENST00000357586,ENST00000405198	In-frame
ENSG00000261437	ENST00000562760	exon_skip_382356	chr3:37091466-37091538	-9.15	-0.1664	LRRFIP2	ENST00000336686	In-frame
ENSG00000261437	ENST00000562760	exon_skip_515330	chrX:65524563-65524614	-10.90	-0.2180	LAS1L	ENST00000374811	In-frame

lncRNA targets by miRNA.

LncRNA Ensembl ID

miRNA ID

LncRNA ENST ID

Binding site in lncRNA

Score

Energy

Align Len

Public source

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Variants for LINC02894

RNA A-to-I editing events in lncRNA.

LncRNAediting ID

LncRNA Ensembl ID

Chromosome

Editing Position

Strand

Gene Type

Gene Name

Transcript ID

Transcript Type

Transcript Name

Edited-associated DElncRNAs in cancer.

LncRNA Ensembl ID

LncRNA Index

Cancer Type

Chr_Postion_Strand

AVE1

AVE2

log2FC

W-value

P-value

Adjc.p-value

Change

Correlation between RNA A-to-I editing events's frequecy and lncRNA expression.

LncRNA Ensembl ID

LncRNA Index

Correlation

P-value

Adjc.p-value

Cis-expression quantitative trait loci(cis-eQTL) of lncRNA.

LncRNA Ensembl ID

LncRNA Name

SNP info

Number of Positive corelated Cancer

Positive corelated Cancer

Number of Negative corelated Cancer

Negative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncRNA regulates differentially expressed genes by function as enhancer.

LncRNA Ensembl ID	PC Gene ID	PC Gene Name	Positive correlated cancers	Cancer with PC gene up-regulation	Cancer with PC gene down-regulation
ENSG00000261437	ENSG00000006625	GGCT	BLCA,CESC,CHOL,COAD,ESCA,KICH,READ,STAD,UCEC	BLCA,CESC,UCEC
ENSG00000261437	ENSG00000035141	FAM136A	BLCA,CESC,CHOL,ESCA,STAD,UCEC	CESC,UCEC
ENSG00000261437	ENSG00000076554	TPD52	BLCA,BRCA,CESC,CHOL,COAD,ESCA,READ	BRCA,CESC
ENSG00000261437	ENSG00000091651	ORC6	BLCA,BRCA,CESC,CHOL,STAD,UCEC	BLCA,BRCA,CESC,CHOL,STAD,UCEC
ENSG00000261437	ENSG00000104218	CSPP1	BLCA,CESC,CHOL,COAD,ESCA,READ,STAD	CHOL
ENSG00000261437	ENSG00000104413	ESRP1	BLCA,BRCA,CESC,CHOL,COAD,KICH,OV,READ,STAD,TGCT,UCEC	BRCA,CESC,CHOL,UCEC
ENSG00000261437	ENSG00000117632	STMN1	BLCA,BRCA,CESC,CHOL,UCEC	BLCA,BRCA,CESC,CHOL,UCEC
ENSG00000261437	ENSG00000119640	ACYP1	BLCA,CESC,CHOL,COAD,ESCA,KICH,READ,STAD	BLCA,CESC,CHOL
ENSG00000261437	ENSG00000119888	EPCAM	BLCA,CESC,CHOL,ESCA,KICH,READ,STAD	BLCA,CHOL
ENSG00000261437	ENSG00000134253	TRIM45	BLCA,CESC,CHOL,KICH,UCEC	CHOL
ENSG00000261437	ENSG00000137343	ATAT1	BLCA,CESC,CHOL,ESCA,STAD	BLCA,CHOL
ENSG00000261437	ENSG00000137547	MRPL15	BLCA,BRCA,STAD,TGCT,UCEC	UCEC
ENSG00000261437	ENSG00000147799	ARHGAP39	BLCA,BRCA,CESC,CHOL,STAD	BLCA,BRCA,CESC,CHOL,STAD
ENSG00000261437	ENSG00000156170	NDUFAF6	BLCA,BRCA,CESC,CHOL,COAD,ESCA,KICH,OV,READ,STAD,UCEC	BRCA
ENSG00000261437	ENSG00000156876	SASS6	BLCA,CHOL,READ,STAD,UCEC	BLCA,STAD
ENSG00000261437	ENSG00000158106	RHPN1	BLCA,CESC,CHOL,ESCA,KICH,STAD	BLCA,CESC,CHOL,STAD
ENSG00000261437	ENSG00000159055	MIS18A	BLCA,BRCA,CHOL,STAD,UCEC	BLCA,BRCA,UCEC
ENSG00000261437	ENSG00000160298	C21orf58	BLCA,BRCA,CESC,CHOL,ESCA,STAD	BLCA,BRCA,CESC,CHOL
ENSG00000261437	ENSG00000160602	NEK8	BLCA,CESC,ESCA,KICH,READ,STAD	CESC
ENSG00000261437	ENSG00000162836	ACP6	BLCA,CESC,CHOL,ESCA,STAD	BLCA
ENSG00000261437	ENSG00000163041	H3-3A	BLCA,CESC,CHOL,KICH,UCEC	CESC
ENSG00000261437	ENSG00000164695	CHMP4C	BLCA,BRCA,CHOL,COAD,ESCA,KICH,STAD	BLCA,CHOL
ENSG00000261437	ENSG00000165209	STRBP	BLCA,CESC,COAD,READ,UCEC	CESC,UCEC
ENSG00000261437	ENSG00000170540	ARL6IP1	BLCA,BRCA,CESC,CHOL,KICH,READ,UCEC	CESC
ENSG00000261437	ENSG00000173681	BCLAF3	BLCA,CHOL,COAD,ESCA,READ	CHOL
ENSG00000261437	ENSG00000176834	VSIG10	BLCA,CESC,CHOL,ESCA,KICH,READ	CHOL
ENSG00000261437	ENSG00000178096	BOLA1	BLCA,CHOL,ESCA,STAD,TGCT	BLCA
ENSG00000261437	ENSG00000182173	TSEN54	BLCA,BRCA,CESC,CHOL,KICH,STAD	BRCA,CESC,CHOL
ENSG00000261437	ENSG00000184678	H2BC21	BLCA,CESC,CHOL,ESCA,KICH,READ	BLCA,CHOL
ENSG00000261437	ENSG00000185917	SETD4	BLCA,CHOL,COAD,STAD,TGCT	CHOL
ENSG00000261437	ENSG00000196476	C20orf96	BLCA,CESC,CHOL,ESCA,KICH,STAD	CHOL
ENSG00000261437	ENSG00000196678	ERI2	BLCA,CESC,CHOL,COAD,ESCA,KICH,READ	CESC
ENSG00000261437	ENSG00000204991	SPIRE2	BLCA,CESC,CHOL,ESCA,STAD	CESC
ENSG00000261437	ENSG00000221886	ZBED8	BLCA,CESC,CHOL,COAD,OV	CHOL
ENSG00000261437	ENSG00000123485	HJURP	BRCA,CHOL,READ,TGCT,UCEC	BRCA,CHOL,UCEC
ENSG00000261437	ENSG00000136982	DSCC1	BRCA,CESC,CHOL,COAD,STAD,TGCT,UCEC	BRCA,CESC,CHOL,STAD,UCEC
ENSG00000261437	ENSG00000147592	LACTB2	BRCA,CESC,CHOL,ESCA,STAD,TGCT	CESC,STAD
ENSG00000261437	ENSG00000149636	DSN1	BRCA,CESC,CHOL,COAD,READ,STAD,TGCT,UCEC	BRCA,CESC,CHOL,STAD,UCEC
ENSG00000261437	ENSG00000156787	TBC1D31	BRCA,COAD,READ,STAD,UCEC	BRCA,STAD
ENSG00000261437	ENSG00000156802	ATAD2	BRCA,CHOL,COAD,READ,STAD	BRCA,STAD
ENSG00000261437	ENSG00000159147	DONSON	BRCA,CESC,CHOL,STAD,TGCT	BRCA,CESC
ENSG00000261437	ENSG00000164754	RAD21	BRCA,CESC,CHOL,COAD,ESCA,KICH,READ,STAD	BRCA
ENSG00000261437	ENSG00000164924	YWHAZ	BRCA,CHOL,COAD,KICH,READ,STAD,UCEC	CHOL
ENSG00000261437	ENSG00000164934	DCAF13	BRCA,CESC,CHOL,COAD,ESCA,KICH,READ,STAD,TGCT,UCEC	BRCA,STAD
ENSG00000261437	ENSG00000167523	SPATA33	BRCA,CESC,CHOL,OV,READ,STAD	CHOL
ENSG00000261437	ENSG00000172172	MRPL13	BRCA,CHOL,COAD,ESCA,KICH,STAD,UCEC	BRCA,UCEC
ENSG00000261437	ENSG00000175279	CENPS	BRCA,CHOL,ESCA,READ,STAD,TGCT,UCEC	BRCA
ENSG00000261437	ENSG00000189376	C8orf76	BRCA,CHOL,READ,STAD,TGCT,UCEC	BRCA
ENSG00000261437	ENSG00000277161	PIGW	BRCA,CESC,COAD,KICH,OV,READ,STAD	CESC,STAD
ENSG00000261437	ENSG00000125885	MCM8	CESC,CHOL,COAD,KICH,STAD,TGCT	CESC,CHOL,STAD
ENSG00000261437	ENSG00000135845	PIGC	CESC,CHOL,ESCA,KICH,STAD,TGCT	CHOL
ENSG00000261437	ENSG00000141570	CBX8	CESC,CHOL,ESCA,KICH,STAD	CESC,CHOL
ENSG00000261437	ENSG00000149346	SLX4IP	CESC,CHOL,KICH,STAD,TGCT	CESC,STAD
ENSG00000261437	ENSG00000105821	DNAJC2	CHOL,COAD,READ,STAD,UCEC	STAD
ENSG00000261437	ENSG00000132680	KHDC4	CHOL,ESCA,READ,STAD,TGCT,UCEC	CHOL

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lncRNAs regulate the target genes through recruiting transcript factors

LncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

LncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).

lncRNA ID

TF ID

TF Name

PCgene ID

PCgene Name

Number of Cancer

Canaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

LncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

LncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.

LncRNA Ensembl ID

RBP ID

RBP Gene Name

Exon Skipping ID

Skipped Exon

EX Gene Name

EX Affected TransID

ORF_anno

Cancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.

LncRNA Ensembl ID	LncRNA ENST ID	PC Gene Name	PC Gene ID	PC ENST ID	dG	nDG	Cancer with PC gene up-regulation	Cancer with PC gene Down-regulation
ENSG00000261437	ENST00000562760	EHD2	ENSG00000024422	ENST00000538399	-0.1146	210	-	BLCA,UCEC,LUSC,BRCA
ENSG00000261437	ENST00000562760	EHD2	ENSG00000024422	ENST00000596225	-0.1083	51	-	BLCA,UCEC,LUSC,BRCA
ENSG00000261437	ENST00000562760	C1R	ENSG00000159403	ENST00000536053	-0.1141	1078	-	CHOL,BLCA,UCEC
ENSG00000261437	ENST00000562760	C1R	ENSG00000159403	ENST00000535233	-0.1141	1078	-	CHOL,BLCA,UCEC

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lncRNAs regulate mRNA by competing with miRNA

lncRNA regulates mRNA by competing the miRNA binding site with mRNA.

LncRNA Ensembl ID

lncRNA-miRNA-mRNA

Cancer Types

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lncRNA coding potential

ORFfinder result for the gencode.v22.lncRNA.transcript.fa.

lncRNA Ensembl ID	lncRNA ENST ID	length(AA)	start at transcript	end at transcript
ENSG00000261437.1	ENST00000562760.1	72	970	752

	lncRNA summary
	lncRNA structure and expression level
	lncRNA-Protein interaction
	lncRNA-DNA interaction
	lncRNA-RNA interaction
	Variants in lncRNA
	lncRNAs regulate the target genes through functioning as enhancers
	lncRNAs regulate the target genes through recruiting transcript factors
	lncRNAs regulate the alternative splicing events through interacting with splicing factor
	lncRNAs regulate mRNA through targeting the 3'-UTR region
	lncRNAs regulate mRNA by competing with miRNA
	lncRNA coding potential