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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000261068

Summary for RP11-7K24.3

check button Gene summary

Gene informationEnsembl ID

ENSG00000261068

Gene symbol

RP11-7K24.3

Gene name
HGNC
Entrez ID
Gene typelincRNA
Synonyms
UniProtAcc

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Structure and expression level for RP11-7K24.3

check buttonAS events and RNA A-to-I editing events of lncRNA in TCGA based on Genvode V22 structure.
UCSC result

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002610681.154483e+025.484813e+005.914667e-019.273241e+001.810000e-209.450000e-19UPCHOL
ENSG000002610685.389577e+023.103097e+008.081337e-013.839831e+001.231190e-041.441792e-03UPCESC
ENSG000002610688.064491e+02-2.141447e+002.155082e-01-9.936732e+002.880000e-238.340000e-22DOWNHNSC
ENSG000002610681.981268e+021.537333e+003.012583e-015.103040e+003.340000e-071.570000e-06UPKIRP
ENSG000002610681.442076e+021.168797e+002.384019e-014.902634e+009.460000e-073.980000e-06UPUCEC
ENSG000002610688.188087e+011.027507e+001.936946e-015.304777e+001.130000e-074.810000e-07UPCOAD
ENSG000002610684.412607e+02-2.058241e+002.920356e-01-7.047912e+001.820000e-123.460000e-11DOWNSTAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002610684.869245e-016.939820e-04CHOL1.279910e-03

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lncRNA-Protein interaction for RP11-7K24.3

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000261068ENST00000562471RP11-7K24.3ENSG00000188786MTF153.5992.6687Q14872TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source

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lncRNA-DNA interaction for RP11-7K24.3

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
RARG,MTF1,PITX1
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-7K24.3

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000261068ENST00000562471exon_skip_44853chr10:104010815-104010908-12.54-0.1672SLKENST00000369755In-frame
ENSG00000261068ENST00000562471exon_skip_57897chr11:35196745-35196874-15.60-0.1268CD44ENST00000428726In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000261068ENST00000562471exon_skip_33516chr1:156938417-156938513-18.27-0.2228ARHGEF11ENST00000361409In-frame
ENSG00000261068ENST00000562471exon_skip_90104chr12:10709907-10710114-26.70-0.1658YBX3ENST00000228251In-frame
ENSG00000261068ENST00000562471exon_skip_293641chr17:76091142-76091235-11.91-0.2206EXOC7ENST00000589210In-frame
ENSG00000261068ENST00000562471exon_skip_368285chr22:29329711-29329720-3.46-0.5767AP1B1ENST00000357586,ENST00000405198In-frame
ENSG00000261068ENST00000562471exon_skip_62840chr11:70421469-70421580-15.21-0.1536CTTNENST00000301843In-frame

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for RP11-7K24.3

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name
LncEditing_165739ENSG00000261068.2chr642092479-lincRNARP11-7K24.3ENST00000562471.2lincRNARP11-7K24.3-001
LncEditing_165740ENSG00000261068.2chr642092481-lincRNARP11-7K24.3ENST00000562471.2lincRNARP11-7K24.3-001
LncEditing_165753ENSG00000261068.2chr642092547-lincRNARP11-7K24.3ENST00000562471.2lincRNARP11-7K24.3-001
LncEditing_165755ENSG00000261068.2chr642092556-lincRNARP11-7K24.3ENST00000562471.2lincRNARP11-7K24.3-001
LncEditing_165781ENSG00000261068.2chr642092665-lincRNARP11-7K24.3ENST00000562471.2lincRNARP11-7K24.3-001
LncEditing_165786ENSG00000261068.2chr642092698-lincRNARP11-7K24.3ENST00000562471.2lincRNARP11-7K24.3-001
LncEditing_165788ENSG00000261068.2chr642092705-lincRNARP11-7K24.3ENST00000562471.2lincRNARP11-7K24.3-001
LncEditing_165794ENSG00000261068.2chr642093401-lincRNARP11-7K24.3ENST00000562471.2lincRNARP11-7K24.3-001
LncEditing_165802ENSG00000261068.2chr642093451-lincRNARP11-7K24.3ENST00000562471.2lincRNARP11-7K24.3-001
LncEditing_165803ENSG00000261068.2chr642093455-lincRNARP11-7K24.3ENST00000562471.2lincRNARP11-7K24.3-001
LncEditing_165810ENSG00000261068.2chr642093487-lincRNARP11-7K24.3ENST00000562471.2lincRNARP11-7K24.3-001
LncEditing_165811ENSG00000261068.2chr642093491-lincRNARP11-7K24.3ENST00000562471.2lincRNARP11-7K24.3-001
LncEditing_165813ENSG00000261068.2chr642093497-lincRNARP11-7K24.3ENST00000562471.2lincRNARP11-7K24.3-001
LncEditing_165814ENSG00000261068.2chr642093523-lincRNARP11-7K24.3ENST00000562471.2lincRNARP11-7K24.3-001
LncEditing_165834ENSG00000261068.2chr642093600-lincRNARP11-7K24.3ENST00000562471.2lincRNARP11-7K24.3-001

check buttonEdited-associated DElncRNAs in cancer.
Differentially expressed gene
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange
ENSG00000261068LncEditing_165786LUSCchr6_42092698_-4.428570e+002.174987e+009.748161e-017.647070e+002.056108e-143.388383e-14UP
ENSG00000261068LncEditing_165755HNSCchr6_42092556_-6.537831e+005.351494e+003.461761e+003.389684e+006.997336e-047.497145e-04UP
ENSG00000261068LncEditing_165802HNSCchr6_42093451_-1.042150e+014.754674e+008.832790e-017.966136e+001.637132e-152.531648e-15UP
ENSG00000261068LncEditing_165803HNSCchr6_42093455_-1.123051e+014.821749e+008.198098e-018.018911e+001.066869e-151.666983e-15UP
ENSG00000261068LncEditing_165834HNSCchr6_42093600_-9.812882e+004.128226e+008.005413e-011.147048e+011.856258e-307.955391e-30UP
ENSG00000261068LncEditing_165786THCAchr6_42092698_-3.177659e+002.854255e+006.457859e+002.572141e+001.010716e-021.077744e-02UP
ENSG00000261068LncEditing_165788THCAchr6_42092705_-3.109028e+002.861945e+008.370483e+002.616840e+008.874787e-039.513149e-03UP
ENSG00000261068LncEditing_165814THCAchr6_42093523_-5.417946e+002.365236e+008.362868e-011.166714e+011.876360e-311.777588e-30UP
ENSG00000261068LncEditing_165834THCAchr6_42093600_-5.185102e+002.503094e+009.517829e-019.613154e+007.036030e-223.137967e-21UP
ENSG00000261068LncEditing_165755CHOLchr6_42092556_-3.178072e+001.811176e+001.232703e+002.114142e+003.450318e-023.772148e-02UP
ENSG00000261068LncEditing_165739OVchr6_42092479_-5.555751e+003.063703e+001.164544e+007.363887e+001.786312e-134.305410e-13UP
ENSG00000261068LncEditing_165740OVchr6_42092481_-5.150358e+003.204084e+001.460364e+005.068065e+004.018801e-075.402467e-07UP
ENSG00000261068LncEditing_165755OVchr6_42092556_-5.448429e+002.655486e+009.644460e-018.667317e+004.424208e-181.663828e-17UP
ENSG00000261068LncEditing_165781OVchr6_42092665_-5.901304e+002.858437e+009.561993e-017.061410e+001.648220e-123.591323e-12UP
ENSG00000261068LncEditing_165786OVchr6_42092698_-4.936076e+002.952913e+001.349117e+007.281390e+003.303980e-137.604529e-13UP
ENSG00000261068LncEditing_165788OVchr6_42092705_-4.959269e+002.808949e+001.219367e+008.246257e+001.634325e-165.173018e-16UP
ENSG00000261068LncEditing_165803OVchr6_42093455_-5.829240e+002.978499e+001.032288e+008.003802e+001.206350e-153.560961e-15UP
ENSG00000261068LncEditing_165811OVchr6_42093491_-5.784404e+003.089629e+001.105296e+007.821325e+005.227012e-151.449846e-14UP
ENSG00000261068LncEditing_165755CESCchr6_42092556_-7.117404e+004.760651e+001.723567e+003.281120e+001.033956e-031.150511e-03UP
ENSG00000261068LncEditing_165788CESCchr6_42092705_-6.429691e+004.774520e+002.328865e+003.022013e+002.510999e-032.715073e-03UP
ENSG00000261068LncEditing_165794CESCchr6_42093401_-9.423009e+004.436790e+009.202413e-015.634352e+001.757175e-083.037828e-08UP
ENSG00000261068LncEditing_165802CESCchr6_42093451_-9.437214e+004.121088e+008.365851e-017.471248e+007.943789e-143.116409e-13UP
ENSG00000261068LncEditing_165786PAADchr6_42092698_-4.409467e+002.201085e+009.976163e-015.184226e+002.169138e-075.061323e-07UP
ENSG00000261068LncEditing_165788PAADchr6_42092705_-3.966481e+002.288470e+001.260278e+003.943342e+008.035393e-051.184163e-04UP
ENSG00000261068LncEditing_165739ESCAchr6_42092479_-7.653885e+008.133170e+00-1.141222e+013.535600e+004.068508e-044.812411e-04DOWN
ENSG00000261068LncEditing_165740ESCAchr6_42092481_-1.052842e+017.384600e+001.954282e+003.751001e+001.761298e-042.150076e-04UP
ENSG00000261068LncEditing_165753ESCAchr6_42092547_-9.921531e+007.764843e+002.828006e+002.131639e+003.303650e-023.351622e-02UP
ENSG00000261068LncEditing_165781ESCAchr6_42092665_-9.647609e+007.618564e+002.935544e+002.973656e+002.942751e-033.246319e-03UP
ENSG00000261068LncEditing_165786ESCAchr6_42092698_-1.016200e+017.126168e+001.953180e+004.472261e+007.739699e-061.105069e-05UP
ENSG00000261068LncEditing_165788ESCAchr6_42092705_-9.961578e+007.373406e+002.303919e+004.330235e+001.489503e-052.051248e-05UP
ENSG00000261068LncEditing_165802ESCAchr6_42093451_-1.223743e+016.888859e+001.206326e+005.365881e+008.055485e-081.519739e-07UP
ENSG00000261068LncEditing_165803ESCAchr6_42093455_-1.255264e+016.516831e+001.057364e+006.188607e+006.069802e-101.673987e-09UP
ENSG00000261068LncEditing_165811ESCAchr6_42093491_-1.056764e+017.217125e+001.817661e+004.905579e+009.315221e-071.503056e-06UP

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value
ENSG00000261068LncEditing_165739-5.165864e-013.306331e-052.049831e-04
ENSG00000261068LncEditing_165740-6.524213e-016.731268e-071.391129e-05
ENSG00000261068LncEditing_165755-3.749003e-016.933127e-053.201039e-04
ENSG00000261068LncEditing_165781-5.578904e-012.932860e-079.791241e-06
ENSG00000261068LncEditing_165786-5.753713e-011.312422e-091.501871e-07
ENSG00000261068LncEditing_165788-5.267440e-012.435059e-092.113631e-07
ENSG00000261068LncEditing_165794-3.058916e-014.952999e-041.257077e-03
ENSG00000261068LncEditing_165802-5.182221e-013.675995e-064.369730e-05
ENSG00000261068LncEditing_165803-4.196049e-016.865946e-041.568327e-03
ENSG00000261068LncEditing_165811-3.848824e-015.782039e-037.891210e-03
ENSG00000261068LncEditing_165786-4.957973e-014.845062e-051.017952e-04
ENSG00000261068LncEditing_165788-4.133495e-016.867741e-049.651960e-04
ENSG00000261068LncEditing_165834-3.268758e-014.475391e-035.142991e-03
ENSG00000261068LncEditing_165786-3.322068e-011.084221e-021.421042e-02
ENSG00000261068LncEditing_165755-4.539875e-011.008728e-041.765274e-04
ENSG00000261068LncEditing_165794-5.425076e-012.112952e-061.023969e-05
ENSG00000261068LncEditing_165802-5.467814e-011.691820e-068.882055e-06
ENSG00000261068LncEditing_165803-6.048339e-011.272524e-067.288094e-06
ENSG00000261068LncEditing_165810-3.417534e-016.119066e-036.883949e-03
ENSG00000261068LncEditing_165813-3.124970e-012.868738e-033.286009e-03
ENSG00000261068LncEditing_165834-3.719203e-012.464359e-055.971331e-05
ENSG00000261068LncEditing_165755-4.175512e-011.515152e-032.756952e-03
ENSG00000261068LncEditing_165788-4.773748e-011.840629e-033.138851e-03
ENSG00000261068LncEditing_165794-4.178451e-012.533331e-034.102138e-03
ENSG00000261068LncEditing_165802-6.740716e-011.356618e-062.973385e-05
ENSG00000261068LncEditing_165803-4.427433e-012.616579e-034.179423e-03
ENSG00000261068LncEditing_165740-6.085774e-011.341072e-042.849960e-03
ENSG00000261068LncEditing_165753-4.464673e-014.247206e-024.547230e-02
ENSG00000261068LncEditing_165755-4.440318e-011.488610e-042.887904e-03
ENSG00000261068LncEditing_165781-5.085840e-012.131575e-038.687513e-03
ENSG00000261068LncEditing_165786-4.336207e-011.854992e-037.689497e-03
ENSG00000261068LncEditing_165788-4.486965e-012.878953e-039.764281e-03
ENSG00000261068LncEditing_165794-4.264747e-013.198787e-043.795357e-03
ENSG00000261068LncEditing_165802-4.948915e-012.508288e-039.435241e-03
ENSG00000261068LncEditing_165803-4.140983e-017.112386e-031.666429e-02
ENSG00000261068LncEditing_165811-5.232195e-015.318477e-044.776780e-03
ENSG00000261068LncEditing_165813-3.296745e-011.417169e-036.760988e-03
ENSG00000261068LncEditing_165814-3.429096e-015.852559e-044.803891e-03
ENSG00000261068LncEditing_165786-5.115251e-011.260082e-021.860122e-02
ENSG00000261068LncEditing_165788-4.352993e-014.857897e-024.909166e-02
ENSG00000261068LncEditing_165788-4.524822e-012.315569e-036.089090e-03
ENSG00000261068LncEditing_165794-6.702317e-011.059995e-051.881491e-04
ENSG00000261068LncEditing_165802-6.179372e-011.357305e-064.818432e-05
ENSG00000261068LncEditing_165803-5.274955e-019.465673e-043.856865e-03

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000261068.2ENST00000562471.24528162