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Center for Computational Systems Medicine
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lncRNA summary

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lncRNA structure and expression level

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lncRNA-Protein interaction

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lncRNA-DNA interaction

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lncRNA-RNA interaction

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Variants in lncRNA

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lncRNAs regulate the target genes through functioning as enhancers

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lncRNAs regulate the target genes through recruiting transcript factors

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lncRNAs regulate the alternative splicing events through interacting with splicing factor

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lncRNAs regulate mRNA through targeting the 3'-UTR region

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lncRNAs regulate mRNA by competing with miRNA

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lncRNA coding potential

lncRNA: ENSG00000260912

Summary for RP11-363E7.4

check button Gene summary

Gene informationEnsembl ID

ENSG00000260912

Gene symbol

RP11-363E7.4

Gene name
HGNC
Entrez ID
Gene typesense_overlapping
Synonyms
UniProtAcc

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Structure and expression level for RP11-363E7.4

check buttonDifferentially expressed gene analysis between cancer and normal samples.
DEG result
Ensembl IDBase meanlog2FC(AD/control)lfcSEStatP-valueAdjc.p-valueDEG direction Cancer type
ENSG000002609126.374720e+021.808237e+009.084600e-021.990442e+013.730000e-881.740000e-85UPTHCA
ENSG000002609128.663967e+02-2.315506e+004.114711e-01-5.627385e+001.830000e-089.110000e-07DOWNESCA
ENSG000002609121.115139e+03-1.711588e+002.623120e-01-6.525008e+006.800000e-119.970000e-10DOWNSTAD

check buttonCorrelation between lncRNAs and cancer stages.
LncRNA Ensembl IDCorrelationP-valueCancer TypeAdjc.p-value
ENSG000002609123.451179e-012.024289e-02CHOL2.199518e-02
ENSG00000260912-4.185656e-014.465111e-05KICH8.229968e-05

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lncRNA-Protein interaction for RP11-363E7.4

lncrna_protein
check buttonlncRNA-epigenetic factor interaction (#cancer types with positive correlation >= 5).
Epi result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000260912ENST00000563205RP11-363E7.4ENSG00000107077KDM4C64.1290.3331Q9H3R0EpiNA
ENSG00000260912ENST00000563205RP11-363E7.4ENSG00000134046MBD220.9391.0321Q9UBB5TF,EpiNA
ENSG00000260912ENST00000563205RP11-363E7.4ENSG00000164985PSIP112.2791.5397O75475EpiNA

check buttonlncRNA-transcript factor interaction (#cancer types with positive correlation >= 5).
TF result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000260912ENST00000563205RP11-363E7.4ENSG00000134046MBD220.9392.2117Q9UBB5TF,EpiNA
ENSG00000260912ENST00000563205RP11-363E7.4ENSG00000196233LCOR14.791.9055Q96JN0TFNA
ENSG00000260912ENST00000563205RP11-363E7.4ENSG00000168661ZNF3014.6892.9767P17039TFNA
ENSG00000260912ENST00000563205RP11-363E7.4ENSG00000197857ZNF4414.6693.5913P15621TFNA
ENSG00000260912ENST00000563205RP11-363E7.4ENSG00000168310IRF213.2592.5097P14316TFNA
ENSG00000260912ENST00000563205RP11-363E7.4ENSG00000198429ZNF6912.6592.525Q9UC07TFNA
ENSG00000260912ENST00000563205RP11-363E7.4ENSG00000170608FOXA311.0191.2725P55318TFNA

check buttonlncRNA-RNA binding protein interaction (#cancer types with positive correlation >= 5).
RBP result
LncRNA Ensembl IDLncRNA ENST IDLncRNA NameProtein Ensembl IDProtein NameCatRAPID ScoreLncpro ScoreUniPortIDGene SubtypePublic source
ENSG00000260912ENST00000563205RP11-363E7.4ENSG00000135870RC3H146.1790.227Q5TC82RBPNA
ENSG00000260912ENST00000563205RP11-363E7.4ENSG00000174720LARP79.7195.2359Q4G0J3RBPNA

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lncRNA-DNA interaction for RP11-363E7.4

lncrna_DNA
check buttonlncRNA targets the enhancer region and positively regulates the gene expression.
Only predicted by TDF
ZNF30,GPX2,MAPK1IP1L,RFK,TMEM168,VSIG2,MST1R,CAPN9,SLC9A1,MED7,PLEKHA7,ATP2A3,FAM214A,MCEE,DNMBP,IP6K2,FGD4,SCP2,KLF4,LYSMD4,STAM2,PSCA,TTC39B,GNAQ,RSBN1,EIF2AK3,CYP2S1,AFTPH,CHP1,CAAP1,SMIM22,SERINC5,FUCA1,C14orf28,TP53INP1,KLHL28,SNAPC1,LARP7,TMEM38A,IFNGR1,KIAA2026,FBXO22,SNX16,IFT74,NBEAL2,PDCD6IP,RC3H1,HIF1A,ZNF44,SPATA18,FBXO34,DNM2,PPP1R2,NUDT12,MFSD9,CCNH,GCNT4,KIFBP,FEM1C,PSIP1,ANAPC10,MBD2,ESRP1,FA2H,GSKIP,ITSN2,SPTLC2,FOXA3,RASEF,RBM47,THAP6,FBXL5,TMEM41B,BCL10,C4orf33,RSBN1L,ZNF57,LCOR,ACOX1,TRAPPC6B,PNPLA8,LPCAT4,IRF2,OSTF1,CCDC125,ANKRA2,C9orf72,LPAR2,GALNT6,SH2D3A,TFF2,MINDY3,OSBPL3,ATG14,PWWP2A,PPP6C,SYTL2,TAX1BP1,METTL14,PPP4R3A,LIPH,MARVELD2,ABHD3,CMTM6,UBA3,EPN3,CREM,BTBD10,VSIG10,TMEM68,S100P,ELOVL6,MANSC1,GOLPH3L,ARHGAP12,NT5C2,ALAD,PIK3C2B,PTBP3,SCAMP1,CDK7,RHBDL2,VPS13A,ZNF69,EAPP,MPZL3,SDCBP2,PCMTD1,SHOC2,JKAMP,CDC37L1,CARD8,BCAS1,ZDHHC21,PDCL
Exist in public source
NA

check buttonlncRNA targets the promoter region and positively regulates the gene expression.

check buttonlncRNA targets the promoter region and negatively regulates the gene expression.

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lncRNA-RNA interaction for RP11-363E7.4

lncrna_RNA
check buttonlncRNA targets the 3'UTR region and negatively regulates the mRNA.

check buttonlncRNA targets the skipped exon region.
-lncRNA and exonskipping events are positively correlated.
lncRNA and exonskipping events positive correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonORF mutation
ENSG00000260912ENST00000563205exon_skip_76409chr11:85711112-85711232-13.36-0.1172SYTL2ENST00000528231In-frame

-lncRNA and exonskipping events are negatively correlated.
lncRNA and exonskipping events negative correlated
LncRNA Ensembl IDLncRNA ENST IDExon IDSkipped ExondGndGGene name with skipped exonTransID with skipped exonLOF
ENSG00000260912ENST00000563205exon_skip_382356chr3:37091466-37091538-8.32-0.1300LRRFIP2ENST00000336686In-frame

check buttonlncRNA targets by miRNA.
LncRNA Ensembl IDmiRNA IDLncRNA ENST IDBinding site in lncRNAScoreEnergyAlign LenPublic source

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Variants for RP11-363E7.4

check buttonRNA A-to-I editing events in lncRNA.
LncRNAediting IDLncRNA Ensembl IDChromosomeEditing PositionStrandGene TypeGene NameTranscript IDTranscript TypeTranscript Name

check buttonEdited-associated DElncRNAs in cancer.
LncRNA Ensembl IDLncRNA IndexCancer TypeChr_Postion_StrandAVE1AVE2log2FCW-valueP-valueAdjc.p-valueChange

check buttonCorrelation between RNA A-to-I editing events's frequecy and lncRNA expression.
LncRNA Ensembl IDLncRNA IndexCorrelationP-valueAdjc.p-value

check buttonCis-expression quantitative trait loci(cis-eQTL) of lncRNA.
LncRNA Ensembl IDLncRNA NameSNP infoNumber of Positive corelated CancerPositive corelated CancerNumber of Negative corelated CancerNegative corelated Cancer

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lncRNAs regulate the target genes through functioning as enhancers

lncrna_enhancer
check buttonlncRNA regulates differentially expressed genes by function as enhancer.
LncRNA Ensembl IDPC Gene IDPC Gene NamePositive correlated cancersCancer with PC gene up-regulationCancer with PC gene down-regulation
ENSG00000260912ENSG00000072954TMEM38AACC,CHOL,ESCA,PAAD,STADSTAD
ENSG00000260912ENSG00000163071SPATA18ACC,THCA,THYM,UCEC,UCSTHCA
ENSG00000260912ENSG00000019102VSIG2BLCA,CHOL,DLBC,ESCA,KIRP,LIHC,PAAD,SARC,STADESCA,STAD
ENSG00000260912ENSG00000049283EPN3BLCA,ESCA,KIRP,PAAD,STADESCA,STAD
ENSG00000260912ENSG00000064787BCAS1BLCA,COAD,ESCA,PAAD,STADSTAD
ENSG00000260912ENSG00000167653PSCABLCA,CHOL,DLBC,ESCA,KIRP,SARC,STADESCA,STAD
ENSG00000260912ENSG00000176928GCNT4BLCA,ESCA,KIRP,STAD,THYMESCA,STAD
ENSG00000260912ENSG00000135773CAPN9CHOL,COAD,ESCA,PAAD,STADESCA,STAD
ENSG00000260912ENSG00000137501SYTL2CHOL,COAD,ESCA,KICH,PAAD,READ,STADESCA
ENSG00000260912ENSG00000160181TFF2CHOL,DLBC,ESCA,SARC,STADESCA,STAD
ENSG00000260912ENSG00000163898LIPHCHOL,COAD,ESCA,KICH,PAAD,THCATHCA
ENSG00000260912ENSG00000164078MST1RCHOL,ESCA,KIRP,PAAD,THCATHCA
ENSG00000260912ENSG00000167600CYP2S1CHOL,KICH,PAAD,STAD,TGCT,THCATHCA
ENSG00000260912ENSG00000163993S100PDLBC,ESCA,KIRP,SARC,STAD,UCSSTAD
ENSG00000260912ENSG00000125775SDCBP2ESCA,PAAD,SARC,STAD,UCSSTAD
ENSG00000260912ENSG00000139132FGD4ESCA,PAAD,READ,SARC,TGCTESCA
ENSG00000260912ENSG00000148218ALADESCA,PAAD,TGCT,THYM,UCSESCA
ENSG00000260912ENSG00000155158TTC39BHNSC,OV,READ,THCA,UCSTHCA
ENSG00000260912ENSG00000170522ELOVL6LAML,PAAD,STAD,TGCT,THCATHCA

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lncRNAs regulate the target genes through recruiting transcript factors

lncrna_TF
check buttonLncRNA-TF complex positively regulates the gene expression by target promoter region (#cancer types with positive correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

check buttonLncRNA-TF complex negatively regulates the gene expression by target promoter region (#cancer types with negative correlation >= 5).
lncRNA IDTF IDTF NamePCgene IDPCgene NameNumber of CancerCanaer Types

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lncRNAs regulate the alternative splicing event through interacting with splicing factor

lncrna_AS
check buttonLncRNA-RBP complex positively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

check buttonLncRNA-RBP complex negatively regulates the exon skippping events by target skipped eoxon region.
LncRNA Ensembl IDRBP IDRBP Gene NameExon Skipping IDSkipped ExonEX Gene NameEX Affected TransIDORF_annoCancer Type

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lncRNAs regulate mRNA through targeting the 3'-UTR region

lncrna_mRNA
check buttonlncRNA regulates differential expressed mRNA by directly targeting 3' UTR region.
LncRNA Ensembl IDLncRNA ENST IDPC Gene NamePC Gene IDPC ENST IDdGnDGCancer with PC gene up-regulationCancer with PC gene Down-regulation

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lncRNAs regulate mRNA by competing with miRNA

lncrna_miRNA
check buttonlncRNA regulates mRNA by competing the miRNA binding site with mRNA.
LncRNA Ensembl IDlncRNA-miRNA-mRNACancer Types

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lncRNA coding potential

check buttonORFfinder result for the gencode.v22.lncRNA.transcript.fa.
lncRNA Ensembl IDlncRNA ENST IDlength(AA)start at transcriptend at transcript
ENSG00000260912.1ENST00000563205.15125180